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In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-kappa B PathwaysDownregulating MAPK and NF-kappa B Pathways Journal article
MOLECULES, 2019,Volume: 24,Issue: 5
Authors:  Zhang, C;  Li, CY;  Jia, XJ;  Wang, K;  Tu, YB;  Wang, RC;  Liu, KC;  Lu, T;  He, CW
Favorite  |  View/Download:20/0  |  Submit date:2020/01/09
Zebrafish  Polyphyllin Vii  Anti-inflammation  Macrophage  Mice  
Differential angiogenic activities of naringin and naringenin in zebrafish in vivo and human umbilical vein endothelial cells in vitro Journal article
Journal of Functional Foods, 2018,Volume: 49,Page: 369-377
Authors:  Linmin Chen;  Binrui Yang;  Benqin Tang;  Guiyi Gong;  Hiotong Kam;  Cheng Gao;  Yan Chen;  Ruibing Wang;  Simon Ming Yuen Lee
Favorite  |  View/Download:17/0  |  Submit date:2018/11/06
Angiogenesis  Huvec  Naringin  Zebrafish  
Supramolecular strategy for reducing the cardiotoxicity of bedaquiline without compromising its antimycobacterial efficacy Conference paper
FOOD AND CHEMICAL TOXICOLOGY, Kunming, PEOPLES R CHINA, AUG 25-30, 2018
Authors:  Kuok, Kit Ieng;  Ng, Phoebe Choi In;  Ji, Xia;  Wang, Chunming;  Yew, Wing Wai;  Chan, Denise P. C.;  Zheng, Jun;  Lee, Simon M. Y.;  Wang, Ruibing
View  |  Adobe PDF(423Kb)  |  Favorite  |  View/Download:586/43  |  Submit date:2018/10/30
Cucurbit[7]Uril  Bedaquiline  Supramolecular Formulation  Cardiotoxicity  Antimycobacterial  
Studying the time course of cardiac responses of the same zebrafish using scalable fish-dock microarchitecture Journal article
SENSORS AND ACTUATORS B-CHEMICAL, 2018,Volume: 268,Page: 245-254
Authors:  Guodong Yu;  Simon Ming-Yuen Lee;  Cheuk-Wing Li
Favorite  |  View/Download:21/0  |  Submit date:2018/10/30
Single-fish Analysis  Water-level Docking  Time-course Normalization  Diphenylurea  Doxorubicin-induced Cardiomyopathy  
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:  Cui, Guozhen;  Xin, Qiqi;  Tseng, Hisa Hui Ling;  Hoi, Maggie PuiMan;  Wang, Yan;  Yang, Binrui;  Choi, InLeng;  Wang, Yuqiang;  Yuan, Rong;  Chen, Keji;  Cong, Weihong;  Lee, Simon MingYuen
View  |  Adobe PDF(3018Kb)  |  Favorite  |  View/Download:503/15  |  Submit date:2018/10/30
Cardioprotection  Angiogenesis  ADTM  Zebrafish  VEGF  
Sodium tanshinone IIA sulfonate promotes endothelial integrity via regulating VE-cadherin dynamics and RhoA/ROCK-mediated cellular contractility and prevents atorvastatin-induced intracerebral hemorrhage in zebrafish Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 350,Page: 32-42
Authors:  Zhou, Zhong-Yan;  Huang, Bin;  Li, Shang;  Huang, Xiao-Hui;  Tang, Jing-Yi;  Kwan, Yiu Wa;  Hoi, Pui Man;  Lee, Simon Ming-Yuen
Favorite  |  View/Download:27/0  |  Submit date:2018/10/30
Sodium Tanshinone Iia Sulfonate  Salvia Miltiorrhiza  Hemorrhagic Stroke  Atorvastatin  Rock  
An efficient platform for generating somatic point mutations with germline transmission in the zebrafish by CRISPR/Cas9-mediated gene editing Journal article
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018,Volume: 293,Issue: 17,Page: 6611-6622
Authors:  Yibo Zhang;  Zhiwei Zhang;  Wei Ge
Favorite  |  View/Download:30/0  |  Submit date:2018/10/30
Somatic Point Mutation  Crispr/cas9  Homology-directed Recombination (Hdr)  Knock-in  Zebrafish  
A novel compound DT-010 protects against doxorubicin-induced cardiotoxicity in zebrafish and H9c2 cells by inhibiting reactive oxygen species-mediated apoptotic and autophagic pathways Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 820,Page: 86-96
Authors:  Tang, Fan;  Zhou, Xinhua;  Wang, Liang;  Shan, Luchen;  Li, Chuwen;  Zhou, Hefeng;  Lee, Simon Ming-Yuen;  Hoi, Maggie Pui-Man
Favorite  |  View/Download:21/0  |  Submit date:2018/10/30
Cardioprotection  Anti-oxidative Stress  Anti-apoptosis  Autophagy Regulation  Zebrafish Cardiotoxicity  H9c2 Cardiomyocytes  
Study on antibacterial performance and biocompatibility of a novel phosphorus-magnesium fiber Journal article
MATERIALS LETTERS, 2017,Volume: 209,Page: 562-565
Authors:  Wu, Wei;  Chen, Jia;  Sun, Da;  Kong, Xiangjun;  Xu, Dake;  Wang, Yi;  Luo, Li;  Zhang, Kun;  Xiao, Keshen;  Wang, Guixue
Favorite  |  View/Download:25/0  |  Submit date:2018/10/30
Biomaterials  Nanoparticles  Phosphorous-magnesium fiber  Antibacterial performance  Zebrafish  
Evaluation in zebrafish model of the toxicity of rhodamine B-conjugated crotamine, a peptide potentially useful for diagnostics and therapeutics Journal article
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2017,Volume: 31,Issue: 11
Authors:  Chan, Judy Yuet-Wa;  Zhou, Hefeng;  Kwan, Yiu Wa;  Chan, Shun Wan;  Radis-Baptista, Gandhi;  Lee, Simon Ming-Yuen
Favorite  |  View/Download:45/0  |  Submit date:2018/10/30
Acute Toxicity  Rhodamine B-crotamine  Screening Of Pharmaceuticals  Venom-derived Peptides  Zebrafish Model