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Canthin-6-One Accelerates Alpha-Synuclein Degradation by Enhancing UPS Activity: Drug Target Identification by CRISPR-Cas9 Whole Genome-Wide Screening Technology Journal article
FRONTIERS IN PHARMACOLOGY, 2019
Authors:  Ning-Ning Yuan;  Cui-Zan Cai;  Ming-Yue Wu;  Qi Zhu;  HuanXing Su;  Min Li;  JiaoYan Ren;  Jie-Qiong Tan;  Jia-Hong Lu
Favorite | View/Download:24/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2020/04/14
Canthin-6-one  Parkinson’s Disease  Alpha-synuclein  Ubiquitin-proteasome-system  Crispr/cas9  Rpn2/psmd1  Pka  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View | Adobe PDF | Favorite | View/Download:560/32 | TC[WOS]:13 TC[Scopus]:0 | Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Physalin B induces cell cycle arrest and triggers apoptosis in breast cancer cells through modulating p53-dependent apoptotic pathway Journal article
BIOMEDICINE & PHARMACOTHERAPY, 2018,Volume: 101,Page: 334-341
Authors:  Wang, Anqi;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Gan, Lishe;  Lin, Ligen
View | Adobe PDF | Favorite | View/Download:521/20 | TC[WOS]:9 TC[Scopus]:0 | Submit date:2018/10/30
Physalin b  Breast Cancer  Cell Cycle  Apoptosis  P53  Akt  
Osimertinib (AZD9291) decreases programmed death ligand-1 in EGFR-mutated non-small cell lung cancer cells Journal article
ACTA PHARMACOLOGICA SINICA, 2017,Volume: 38,Issue: 11,Page: 1512-1520
Authors:  Jiang, Xiao-Ming;  Xu, Yu-Lian;  Huang, Mu-Yang;  Zhang, Le-Le;  Su, Min-Xia;  Chen, Xiuping;  Lu, Jin-Jian
Favorite | View/Download:26/0 | TC[WOS]:16 TC[Scopus]:0 | Submit date:2018/10/30
Non-small Cell Lung Cancer  Egfr  Osimertinib  Pd-l1  Ubiquitin-proteasome System  Mg-132  Bortezomib  Gsk3 Beta  Licl  
Schisandrin B reverses doxorubicin resistance through inhibiting P-glycoprotein and promoting proteasome-mediated degradation of survivin Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Wang, Shengpeng;  Wang, Anqi;  Shao, Min;  Lin, Ligen;  Li, Peng;  Wang, Yitao
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Angiotensin II induces connective tissue growth factor expression in human hepatic stellate cells by a transforming growth factor beta-independent mechanism Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Li, Ao;  Zhang, Jingyao;  Zhang, Xiaoxun;  Wang, Jun;  Wang, Songsong;  Xiao, Xiao;  Wang, Rui;  Li, Peng;  Wang, Yitao
View | Adobe PDF | Favorite | View/Download:515/6 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2018/10/30
Big data analysis of global advances in pharmaceutics and drug delivery 1980-2014 Journal article
DRUG DISCOVERY TODAY, 2017,Volume: 22,Issue: 8,Page: 1201-1208
Authors:  Zhang, Weixiang;  Zhao, Qianqian;  Deng, Junling;  Hu, Yuanjia;  Wang, Yitao;  Ouyang, Defang
View | Adobe PDF | Favorite | View/Download:554/13 | TC[WOS]:5 TC[Scopus]:0 | Submit date:2018/10/30
Arctigenin suppresses renal interstitial fibrosis in a rat model of obstructive nephropathy Journal article
PHYTOMEDICINE, 2017,Volume: 30,Page: 28-41
Authors:  Li, Ao;  Zhang, Xiaoxun;  Shu, Mao;  Wu, Mingjun;  Wang, Jun;  Zhang, Jingyao;  Wang, Rui;  Li, Peng;  Wang, Yitao
View | Adobe PDF | Favorite | View/Download:489/5 | TC[WOS]:17 TC[Scopus]:0 | Submit date:2018/10/30
Arctigenin  Renal Fibrosis  Inflammation  Transforming Growth Factor-beta 1  Oxidative Stress  Epithelial-mesenchymal Transition  
Natural products as inhibitorsof the ubiquitin-/ubiquitin-likeprotein-proteasome pathway Book
2012
Authors:  Ma D.-L.;  Pui-Yan Ma V.;  Shiu-Hin Chan D.;  Leung K.-H.;  Zhong H.-J.;  Leung C.-H.
Favorite | View/Download:4/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2018/11/06
Alkaloids Isolated from Natural Herbs as the Anticancer Agents Journal article
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2012,Issue: 4,Page: 623-644
Authors:  Lu, JJ (Lu, Jin-Jian);  Bao, JL (Bao, Jiao-Lin);  Chen, XP (Chen, Xiu-Ping);  HHuang, M (Huang, Min);  Wang, YT (Wang, Yi-Tao)
View | Adobe PDF | Favorite | View/Download:576/74 | TC[WOS]:96 TC[Scopus]:0 | Submit date:2018/11/01
Cell-cycle Arrest  Sanguinarine-induced Apoptosis  Suppresses Tumor-growth  Swiss Albino Mice  Matrine Inhibits Proliferation  Hepatocellular-carcinoma Cells  Mediated Multidrug-resistance  Buccal Pouch Carcinogenesis  Berberine-induced Apoptosis  Induced Lung Carcinogenesis