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Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Sun,Xianding;  Zhou,Yang;  Zhang,Ruobin;  Wang,Zuqiang;  Xu,Meng;  Zhang,Dali;  Huang,Junlan;  Luo,Fengtao;  Li,Fangfang;  Ni,Zhenhong;  Zhou,Siru;  Chen,Hangang;  Chen,Shuai;  Chen,Liang;  Du,Xiaolan;  Chen,Bo;  Huang,Haiyang;  Liu,Peng;  Yin,Liangjun;  Qiu,Juhui;  Chen,Di;  Deng,Chuxia;  Xie,Yangli;  Luo,Lingfei;  Chen,Lin
Favorite | View/Download:256/0 | TC[WOS]:1 TC[Scopus]:2 | Submit date:2020/09/16
Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 838,Page: 41-52
Authors:  Yang, Zheng;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
Favorite | View/Download:35/0 | TC[WOS]:3 TC[Scopus]:4 | Submit date:2018/10/30
Dichloroacetophenone  Epidermal Growth Factor Receptor  Tyrosine Kinase Inhibitor  Synergism  Hypoxia  Oxidative Phosphorylation  
Ponatinib exerts anti-angiogenic effects in the zebrafish and human umbilical vein endothelial cells via blocking VEGFR signaling pathway Journal article
Oncotarget, 2018,Volume: 9,Issue: 62,Page: 31958-31970
Authors:  Nana Ai;  Cheong-Meng Chong.;  Weiting Chen;  Zhe Hu;  Huanxing Su;  Guokai Chen;  Queenie Wing Lei Wong;  Wei Ge
Favorite | View/Download:22/0 | TC[WOS]:0 TC[Scopus]:6 | Submit date:2018/12/11
Angiogenesis  Enos  Huvec  Mapk  Ponatinib  
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:  Cui, Guozhen;  Xin, Qiqi;  Tseng, Hisa Hui Ling;  Hoi, Maggie PuiMan;  Wang, Yan;  Yang, Binrui;  Choi, InLeng;  Wang, Yuqiang;  Yuan, Rong;  Chen, Keji;  Cong, Weihong;  Lee, Simon MingYuen
View | Adobe PDF | Favorite | View/Download:528/16 | TC[WOS]:4 TC[Scopus]:5 | Submit date:2018/10/30
Cardioprotection  Angiogenesis  ADTM  Zebrafish  VEGF  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View | Adobe PDF | Favorite | View/Download:586/38 | TC[WOS]:13 TC[Scopus]:17 | Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Signalling pathways regulating galactosaminoglycan synthesis and structure in vascular smooth muscle: Implications for lipoprotein binding and atherosclerosis Journal article
PHARMACOLOGY & THERAPEUTICS, 2018,Volume: 187,Page: 88-97
Authors:  Afroz, Rizwana;  Cao, Yingnan;  Rostam, Muhamad Ashraf;  Ta, Hang;  Xu, Suowen;  Zheng, Wenhua;  Osman, Narin;  Kamato, Danielle;  Little, Peter J.
Favorite | View/Download:28/0 | TC[WOS]:8 TC[Scopus]:14 | Submit date:2018/10/30
Atherosclerosis  Proteoglycans  Galactosaminoglycans  Signalling Pathways  
Silencing stem cell factor gene in fibroblasts to regulate paracrine factor productions and enhance c-Kit expression in melanocytes on melanogenesis Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 5
Authors:  Li P.-H.;  Liu L.-H.;  Chang C.-C.;  Gao R.;  Leung C.-H.;  Ma D.-L.;  David Wang H.-M.
Favorite | View/Download:11/0 | TC[WOS]:10 TC[Scopus]:15 | Submit date:2018/11/06
Fibroblasts  Melanin  Melanocytes  Paracrine Factors  Stem Cell Factor  
Increased expression of IRE1α associates with the resistant mechanism of osimertinib (AZD9291)-resistant non-small cell lung cancer HCC827/OSIR cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 4,Page: 550-555
Authors:  Tang Z.-H.;  Su M.-X.;  Guo X.;  Jiang X.-M.;  Jia L.;  Chen X.;  Lu J.-J.
Favorite | View/Download:11/0 | TC[WOS]:2 TC[Scopus]:7 | Submit date:2018/12/28
Azd9291  Egfr  Ire1α  Lune Cancer  Nsclc  Osimertinib  
Osimertinib resistance in non-small cell lung cancer: Mechanisms and therapeutic strategies Journal article
CANCER LETTERS, 2018,Volume: 420,Page: 242-246
Authors:  Tang, Zheng-Hai;  Lu, Jin-Jian
Favorite | View/Download:28/0 | TC[WOS]:26 TC[Scopus]:37 | Submit date:2018/10/30
Osimertinib  Azd9291  Egfr Tki  Resistant Mechanisms  Therapeutic Strategies  
Combination Strategies Using EGFR-TKi in NSCLC Therapy: Learning from the Gap between Pre-Clinical Results and Clinical Outcomes Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2018,Volume: 14,Issue: 2,Page: 204-216
Authors:  Yang, Zheng;  Tam, Kin Yip
Favorite | View/Download:25/0 | TC[WOS]:25 TC[Scopus]:30 | Submit date:2018/10/30
Combination  Egfr-tki  Nsclc  Chemotherapy  Targeted Therapy  Immunotherapy