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Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 9,Page: 1193-1204
Authors:  Ting-ting Zhou;  Tong Zhao;  Fei Ma;  Yi-nan Zhang;  Jing Jiang;  Yuan Ruan;  Qiu-ying Yan;  Gai-hong Wang;  Jin Ren;  Xiao-wei Guan;  Jun Guo;  Yong-hua Zhao;  Ji-ming Ye;  Li-hong Hu;  Jing Chen;  Xu Shen
Favorite | View/Download:11/0 | TC[WOS]:1 TC[Scopus]:1 | Submit date:2020/04/14
Type 2 Diabetes Mellitus  Hepatic Gluconeogenesis  Ampk Signaling Pathway  (e)-3-(2-(Quinoline-4-yl)Vinyl)-1h-indol-6-ol (Qvo)  4-[2-(1h-indol-3-yl)Vinyl]Quinoline (Ivq)  Prodrug  
Regulation of glucose metabolism by bioactive phytochemicals for the management of type 2 diabetes mellitus Conference paper
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, Kunming, PEOPLES R CHINA, 2018-8
Authors:  Chao Zhao;  Chengfeng Yang;  Sydney Tang Chi Wai;  Yanbo Zhang;  Maria P. Portillo;  Paolo Paoli;  Yijing Wu;  Wai San Cheang;  Bin Liu;  Christian Carpéné;  Jianbo Xiao;  Hui Cao
Favorite | View/Download:20/0 | TC[WOS]:26 TC[Scopus]:33 | Submit date:2020/04/27
Type 2 Diabetes  Metabolic Pathways  Gut Microbiota  Phytochemicals  New Therapies  
Is metformin still the most efficacious first-line oral hypoglycaemic drug in treating type 2 diabetes? A network meta-analysis of randomized controlled trials Journal article
OBESITY REVIEWS, 2019,Volume: 20,Issue: 1,Page: 1-12
Authors:  Jia, Y.;  Lao, Y.;  Zhu, H.;  Li, N.;  Leung, S. -W.
Favorite | View/Download:36/0 | TC[WOS]:9 TC[Scopus]:12 | Submit date:2019/01/17
Hypoglycaemic Control  Network Meta-analysis  Randomized Controlled Trials  Type 2 Diabetes  
Inhibiting Glycogen Synthase Kinase 3 Reverses Obesity-Induced White Adipose Tissue Inflammation by Regulating Apoptosis Inhibitor of Macrophage/CD5L-Mediated Macrophage Migration Journal article
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2018,Volume: 38,Issue: 9,Page: 2103-2116
Authors:  Wang, Li;  Wang, Yuan;  Zhang, Chao;  Li, Jingjing;  Meng, Yuan;  Dou, Man;  Noguchi, Constance Tom;  Di, Lijun
Favorite | View/Download:38/0 | TC[WOS]:5 TC[Scopus]:7 | Submit date:2018/10/30
Adipose Tissue  Gsk3  Inflammation  Macrophages  Obesity  
Identification of a rhodium(III) complex as a Wee1 inhibitor against TP53-mutated triple-negative breast cancer cells Journal article
CHEMICAL COMMUNICATIONS, 2018,Volume: 54,Issue: 20,Page: 2463-2466
Authors:  Yang, Guan-Jun;  Zhong, Hai-Jing;  Ko, Chung-Nga;  Wong, Suk-Yu;  Vellaisamy, Kasipandi;  Ye, Min;  Ma, Dik-Lung;  Leung, Chung-Hang
View | Adobe PDF | Favorite | View/Download:586/38 | TC[WOS]:18 TC[Scopus]:19 | Submit date:2018/10/30
Building molecular interaction networks from microarray data for drug target screening Book
2018
Authors:  Yuen S.C.;  Zhu H.;  Leung S.-W.
Favorite | View/Download:8/0 | TC[WOS]:0 TC[Scopus]:2 | Submit date:2019/01/15
Differentially expressed genes  Drug targets  Microarray  R  Type 2 diabetes mellitus  
Building molecular interaction networks from microarray data for drug target screening Book chapter
出自: Methods in Molecular Biology, 2018, 页码: 179-197
Authors:  Yuen,Sze Chung;  Zhu,Hongmei;  Leung,Siu wai
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Differentially expressed genes  Drug targets  Microarray  R  Type 2 diabetes mellitus  
Lysosomal Ca2+ Signaling Regulates High Glucose-Mediated Interleukin-1β Secretion via Transcription Factor EB in Human Monocytic Cells Journal article
PLANT JOURNAL, 2017,Volume: 92,Issue: 3,Page: 452-468
Authors:  Hisa Hui Ling Tseng;  Chi Teng Vong;  Yiu Wa Kwan;  Simon Ming Yuen Lee;  Maggie Pui Man Hoi
Favorite | View/Download:14/0 | TC[WOS]:48 TC[Scopus]:10 | Submit date:2020/05/07
High Glucose  Lysosomal Ca2++++  Ca2++++ Homeostasis  Lysosomal Exocytosis  Interleukin-1β  Monocytes  
Differential HbA1c response in the placebo arm of DPP-4 inhibitor clinical trials conducted in China compared to other countries: A systematic review and meta-analysis Journal article
BMC Pharmacology and Toxicology, 2016,Volume: 17,Issue: 1
Authors:  He L.;  Liu S.;  Shan C.;  Tu Y.;  Li Z.;  Zhang X.D.
Favorite | View/Download:7/0 | TC[WOS]:2 TC[Scopus]:2 | Submit date:2018/12/21
Diabetes mellitus  Differential HbA1c response  Dipeptidyl peptidase-4 inhibitor  Meta-analysis  T2DM  
Antrodia camphorata increases insulin secretion and protects from apoptosis in MIN6 cells Journal article
Frontiers in Pharmacology, 2016,Volume: 7,Issue: MAR
Authors:  Chi Teng Vong;  Hisa Hui Ling Tseng;  Yiu Wa Kwan;  Simon Ming-Yuen Lee;  Maggie Pui Man Hoi
Favorite | View/Download:9/0 | TC[WOS]:4 TC[Scopus]:4 | Submit date:2018/11/06
Antrodia Camphorata  Insulin Secretion  Pancreatic Β-cell Death  Ppar-γ  Type 2 Diabetes Mellitus