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Is metformin still the most efficacious first-line oral hypoglycaemic drug in treating type 2 diabetes? A network meta-analysis of randomized controlled trials Journal article
OBESITY REVIEWS, 2019,Volume: 20,Issue: 1,Page: 1-12
Authors:  Jia, Y.;  Lao, Y.;  Zhu, H.;  Li, N.;  Leung, S. -W.
Favorite  |  View/Download:19/0  |  Submit date:2019/01/17
hypoglycaemic control  network meta-analysis  randomized controlled trials  type 2 diabetes  
Inhibiting Glycogen Synthase Kinase 3 Reverses Obesity-Induced White Adipose Tissue Inflammation by Regulating Apoptosis Inhibitor of Macrophage/CD5L-Mediated Macrophage Migration Journal article
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2018,Volume: 38,Issue: 9,Page: 2103-2116
Authors:  Wang, Li;  Wang, Yuan;  Zhang, Chao;  Li, Jingjing;  Meng, Yuan;  Dou, Man;  Noguchi, Constance Tom;  Di, Lijun
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Adipose Tissue  Gsk3  Inflammation  Macrophages  Obesity  
Identification of a rhodium(III) complex as a Wee1 inhibitor against TP53-mutated triple-negative breast cancer cells Journal article
CHEMICAL COMMUNICATIONS, 2018,Volume: 54,Issue: 20,Page: 2463-2466
Authors:  Yang, Guan-Jun;  Zhong, Hai-Jing;  Ko, Chung-Nga;  Wong, Suk-Yu;  Vellaisamy, Kasipandi;  Ye, Min;  Ma, Dik-Lung;  Leung, Chung-Hang
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Building molecular interaction networks from microarray data for drug target screening Book
2018
Authors:  Yuen S.C.;  Zhu H.;  Leung S.-W.
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Differentially expressed genes  Drug targets  Microarray  R  Type 2 diabetes mellitus  
Lysosomal Ca2+ signaling regulates high glucose-mediated interleukin-1β secretion via transcription factor EB in human monocytic cells Journal article
Frontiers in Immunology, 2017,Volume: 8,Issue: SEP
Authors:  Tseng H.H.L.;  Vong C.T.;  Kwan Y.W.;  Lee S.M.-Y.;  Hoi M.P.M.
Favorite  |  View/Download:1/0  |  Submit date:2018/11/06
Ca2+ homeostasis  High glucose  Interleukin-1β  Lysosomal Ca2+  Lysosomal exocytosis  Monocytes  
Lysosomal Ca2+ Signaling REgulates High Glucose-Mediated Interleukin-1 beta Secretion via Transcription Factor EB in Human Monocytic Cells Journal article
FRONTIERS IN IMMUNOLOGY, 2017,Volume: 8
Authors:  Tseng, Hisa Hui Ling;  Vong, Chi Teng;  Kwan, Yiu Wa;  Lee, Simon Ming-Yuen;  Hoi, Maggie Pui Man
Favorite  |  View/Download:11/0  |  Submit date:2018/10/30
high glucose  lysosomal Ca2+  Ca2+ homeostasis  lysosomal exocytosis  interleukin-1 beta  monocytes  
Differential HbA1c response in the placebo arm of DPP-4 inhibitor clinical trials conducted in China compared to other countries: A systematic review and meta-analysis Journal article
BMC Pharmacology and Toxicology, 2016,Volume: 17,Issue: 1
Authors:  He L.;  Liu S.;  Shan C.;  Tu Y.;  Li Z.;  Zhang X.D.
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Diabetes mellitus  Differential HbA1c response  Dipeptidyl peptidase-4 inhibitor  Meta-analysis  T2DM  
Antrodia camphorata increases insulin secretion and protects from apoptosis in MIN6 cells Journal article
Frontiers in Pharmacology, 2016,Volume: 7,Issue: MAR
Authors:  Vong C.T.;  Tseng H.H.L.;  Kwan Y.W.;  Lee S.M.-Y.;  Hoi M.P.M.
Favorite  |  View/Download:2/0  |  Submit date:2018/11/06
Antrodia Camphorata  Insulin Secretion  Pancreatic Β-cell Death  Ppar-γ  Type 2 Diabetes Mellitus  
TRPM2 regulates TXNIP-mediated NLRP3 inflammasome activation via interaction with p47 phox under high glucose in human monocytic cells Journal article
Scientific Reports, 2016,Volume: 6
Authors:  Tseng H.H.L.;  Vong C.T.;  Kwan Y.W.;  Lee S.M.-Y.;  Hoi M.P.M.
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In vitro Vitamin K2 and 1α,25-dihydroxyvitamin D3 combination enhances osteoblasts anabolism of diabetic mice Journal article
European Journal of Pharmacology, 2015,Volume: 767,Page: 30-40
Authors:  Poon C.C.W.;  Li R.W.S.;  Seto S.W.;  Kong S.K.;  Ho H.P.;  Hoi M.P.M.;  Lee S.M.Y.;  Ngai S.M.;  Chan S.W.;  Leung G.P.H.;  Kwan Y.W.
Favorite  |  View/Download:6/0  |  Submit date:2018/11/06
1,25(OH)2D3  Osteoblasts  Osteoporosis  Type 2 diabetes mellitus  Vitamin K2