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Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
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Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Co-delivery of paclitaxel and tetrandrine via iRGD peptide conjugated lipid-polymer hybrid nanoparticles overcome multidrug resistance in cancer cells Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Zhang, Jinming;  Wang, Lu;  Chan, Hon Fai;  Xie, Wei;  Chen, Sheng;  He, Chengwei;  Wang, Yitao;  Chen, Meiwan
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Osthole inhibited TGF beta-induced epithelial-mesenchymal transition (EMT) by suppressing NF-kappa B mediated Snail activation in lung cancer A549 cells Journal article
CELL ADHESION & MIGRATION, 2017,Volume: 11,Issue: 5-6,Page: 464-475
Authors:  Feng, Haitao;  Lu, Jin-Jian;  Wang, Yitao;  Pei, Lixia;  Chen, Xiuping
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Emt  Nf-kappa b  Osthole Snail  Tgf-beta 1  
Alkaloids Isolated from Natural Herbs as the Anticancer Agents Journal article
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2012,Issue: 4,Page: 623-644
Authors:  Lu, JJ (Lu, Jin-Jian);  Bao, JL (Bao, Jiao-Lin);  Chen, XP (Chen, Xiu-Ping);  HHuang, M (Huang, Min);  Wang, YT (Wang, Yi-Tao)
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Cell-cycle Arrest  Sanguinarine-induced Apoptosis  Suppresses Tumor-growth  Swiss Albino Mice  Matrine Inhibits Proliferation  Hepatocellular-carcinoma Cells  Mediated Multidrug-resistance  Buccal Pouch Carcinogenesis  Berberine-induced Apoptosis  Induced Lung Carcinogenesis  
Multi-Target Drugs: The Trend of Drug Research and Development Journal article
PLOS ONE, 2012,Volume: 7,Issue: 6,Page: 30-46
Authors:  Lu, JJ (Lu, Jin-Jian);  Pan, W (Pan, Wei);  Hu, YJ (Hu, Yuan-Jia);  Wang, YT (Wang, Yi-Tao
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Cancer-therapy  Alzheimers-disease  Parkinsons-disease  Attractive Target  Natural-products  b Inhibitors  Discovery  Atherosclerosis  Acetylcholinesterase  Proliferation  
Curcumin induces DNA damage and caffeine-insensitive cell cycle arrest in colorectal carcinoma HCT116 cells Journal article
Molecular and Cellular Biochemistry, 2011,Volume: 354,Issue: 1-2,Page: 247-252
Authors:  Lu J.-J.;  Cai Y.-J.;  Ding J.
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Caffeine  Curcumin  Dna Damage  Mitosis Arrest  s Phase Arrest  Tubulin  
Bis(12)-hupyridone, a novel multifunctional dimer, promotes neuronal differentiation more potently than its monomeric natural analog huperzine A possibly through alpha7 nAChR Journal article
BRAIN RESEARCH, 2011,Volume: 1401,Issue: 15,Page: 10-17
Authors:  Cui, Wei;  Cui, Guo-Zhen;  Li, Wenming;  Zhang, Zaijun;  Hu, Shengquan;  Mak, Shinghung;  Zhang, Huan;  Carlier, Paul R.;  Choi, Chung-lit;  Wong, Yi-Tao;  Lee, Simon Ming-Yuen;  Han, Yifan
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Bis(12)-hupyridone  Huperzine a  Neural Stem Cell  Neurodegenerative Disorder  Differentiation  Alpha 7nachr  
MEK1/2 regulates microtubule organization, spindle pole tethering and asymmetric division during mouse oocyte meiotic maturation Journal article
Cell Cycle, 2007,Volume: 6,Issue: 3,Page: 330-338
Authors:  Yu L.-Z.;  Xiong B.;  Gao W.-X.;  Wang C.-M.;  Zhong Z.-S.;  Huo L.-J.;  Wang Q.;  Hou Y.;  Liu K.;  Liu X.J.;  Schatten H.;  Chen D.-Y.;  Sun Q.-Y.
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Centrosomal Proteins  Meiotic Maturation  Mek  Mouse Oocytes  Spindle  
Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines Journal article
Bioorganic and Medicinal Chemistry Letters, 2006,Volume: 16,Issue: 5,Page: 1191-1196
Authors:  Ouyang X.;  Piatnitski E.L.;  Pattaropong V.;  Chen X.;  He H.-Y.;  Kiselyov A.S.;  Velankar A.;  Kawakami J.;  Labelle M.;  Smith II L.;  Lohman J.;  Lee S.P.;  Malikzay A.;  Fleming J.;  Gerlak J.;  Wang Y.;  Rosler R.L.;  Zhou K.;  Mitelman S.;  Camara M.;  Surguladze D.;  Doody J.F.;  Tuma M.C.
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1,3,4-Oxadiazole  Antimitotic agent  Multiple-drug resistance  Tubulin polymerization inhibitor  
Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors Journal article
Bioorganic and Medicinal Chemistry Letters, 2005,Volume: 15,Issue: 23,Page: 5154-5159
Authors:  Ouyang X.;  Chen X.;  Piatnitski E.L.;  Kiselyov A.S.;  He H.-Y.;  Mao Y.;  Pattaropong V.;  Yu Y.;  Kim K.H.;  Kincaid J.;  Smith II L.;  Wong W.C.;  Lee S.P.;  Milligan D.L.;  Malikzay A.;  Fleming J.;  Gerlak J.;  Deevi D.;  Doody J.F.;  Chiang H.-H.;  Patel S.N.;  Wang Y.;  Rolser R.L.;  Kussie P.;  Labelle M.;  Tuma M.C.
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1,2,4-Triazole  Antimitotic  Tubulin inhibitor  Tubulin polymerization  Tumor vasculature  Vascular disrupting agent