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A Mechanistic Overview of Triptolide and Celastrol, Natural Products from Tripterygium wilfordii Hook F Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Chen, Shao-Ru;  Dai, Yan;  Zhao, Jing;  Lin, Ligen;  Wang, Yitao;  Wang, Ying
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
Tripterygium Wilfordii Hook f  Triptolide  Celastrol  Mechanisms Of Action  Structure-activity-relationship  
Celastrol induced DNA damage, cell cycle arrest, and apoptosis in human rheumatoid fibroblast-like synovial cells Journal article
American Journal of Chinese Medicine, 2013,Volume: 41,Issue: 3,Page: 615
Authors:  Xu Z.;  Wu G.;  Wei X.;  Chen X.;  Wang Y.;  Chen L.
Favorite  |  View/Download:8/0  |  Submit date:2018/10/31
Apoptosis  Celastrol  Dna Damage  Rheumatoid Fibroblast-like Synoviocytes  
Triptolide (TPL) inhibits global transcription by inducing proteasome-dependent degradation of RNA polymerase II (Pol II) Journal article
PLoS ONE, 2011,Volume: 6,Issue: 9
Authors:  Wang Y.;  Lu J.-J.;  He L.;  Yu Q.
Favorite  |  View/Download:1/0  |  Submit date:2018/12/28
Triptolide inhibits the differentiation of Th17 cells and suppresses collagen-induced arthritis Journal article
Scandinavian Journal of Immunology, 2008,Volume: 68,Issue: 4,Page: 383-390
Authors:  Wang Y.;  Jia L.;  Wu C.-Y.
Favorite  |  View/Download:0/0  |  Submit date:2019/01/16
Triptolide modulates T-cell inflammatory responses and ameliorates experimental autoimmune encephalomyelitis Journal article
Journal of Neuroscience Research, 2008,Volume: 86,Issue: 11,Page: 2441-2449
Authors:  Wang Y.;  Mei Y.;  Feng D.;  Xu L.
Favorite  |  View/Download:1/0  |  Submit date:2019/01/16
Experimental autoimmune encephalomyelitis  Multiple sclerosis  NF-κB  Triptolide