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Quinazolinone azolyl ethanols: Potential lead antimicrobial agents with dual action modes targeting methicillin-resistant Staphylococcus aureus DNA Journal article
Future Medicinal Chemistry, 2016,Volume: 8,Issue: 16,Page: 1927-1940
Authors:  Peng X.-M.;  Peng L.-P.;  Li S.;  Avula S.R.;  Kannekanti V.K.;  Zhang S.-L.;  Tam K.Y.;  Zhou C.-H.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/18
Antibacterial  Antifungal  Dna Cleavage  Dna Intercalation  Imidazole  Quinazolinone  Triazole  
Divergence of antiangiogenic activity and hepatotoxicity of different stereoisomers of itraconazole Journal article
Clinical Cancer Research, 2016,Volume: 22,Issue: 11,Page: 2709-2720
Authors:  Shim J.S.;  Li R.-J.;  Bumpus N.N.;  Head S.A.;  Pasunooti K.K.;  Yang E.J.;  Lv J.;  Shi W.;  Liu J.O.
Favorite  |  View/Download:2/0  |  Submit date:2019/01/15
Divergence of anti-angiogenic activity and hepatotoxicity of different stereoisomers of itraconazole Journal article
Clinical Cancer Research, 2016,Volume: 22,Issue: 11,Page: 2709-2720
Authors:  Joong Sup Shim;  Ruo-Jing Li;  Namandje N. Bumpus;  Sarah A. Head;  Kalyan Kumar;  Eun Ju Yang;  Junfang Lv;  Wei Shi;  Jun O. Liu
Favorite  |  View/Download:2/0  |  Submit date:2019/01/24
Itraconazole  Stereoisomers  Drug Repositioning  Angiogenesis  Hepatotoxicity  
Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors Journal article
Bioorganic and Medicinal Chemistry Letters, 2005,Volume: 15,Issue: 23,Page: 5154-5159
Authors:  Ouyang X.;  Chen X.;  Piatnitski E.L.;  Kiselyov A.S.;  He H.-Y.;  Mao Y.;  Pattaropong V.;  Yu Y.;  Kim K.H.;  Kincaid J.;  Smith II L.;  Wong W.C.;  Lee S.P.;  Milligan D.L.;  Malikzay A.;  Fleming J.;  Gerlak J.;  Deevi D.;  Doody J.F.;  Chiang H.-H.;  Patel S.N.;  Wang Y.;  Rolser R.L.;  Kussie P.;  Labelle M.;  Tuma M.C.
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1,2,4-Triazole  Antimitotic  Tubulin inhibitor  Tubulin polymerization  Tumor vasculature  Vascular disrupting agent