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Postnatal deletion of Alk5 gene in meniscal cartilage accelerates age-dependent meniscal degeneration in mice Journal article
Journal of Cellular Physiology, 2019,Volume: 234,Issue: 1,Page: 595-605
Authors:  Wang Q.;  Tan Q.;  Xu W.;  Kuang L.;  Zhang B.;  Wang Z.;  Ni Z.;  Su N.;  Jin M.;  Li C.;  Jiang W.;  Huang J.;  Li F.;  Zhu Y.;  Chen H.;  Du X.;  Chen D.;  Deng C.;  Qi H.;  Xie Y.;  Chen L.
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Activing Receptor-like Kinases 5 (Alk5)  Matrix Degradation  Meniscal Degeneration  Transforming Growth Factor-β (Tgf-β) Signaling  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
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Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Generation of Smurf2 conditional knockout mice Journal article
International Journal of Biological Sciences, 2018,Volume: 14,Issue: 5,Page: 542-548
Authors:  Tang Y.;  Tang L.-Y.;  Xu X.;  Li C.;  Deng C.;  Zhang Y.E.
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Knockout  Liver  Loxp  Mice  Smurf2  
Flavopiridol Inhibits TGF-beta-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2 Journal article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2018,Volume: 365,Issue: 1,Page: 156-164
Authors:  Rostam, Muhamad A.;  Shajimoon, Aravindra;  Kamato, Danielle;  Mitra, Partha;  Piva, Terrence J.;  Getachew, Robel;  Cao, Yingnan;  Zheng, Wenhua;  Osman, Narin;  Little, Peter J.
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Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-beta-Smad signaling pathway Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 341,Page: 38-50
Authors:  Zhou, Fayang;  Wang, Anqi;  Li, Dan;  Wang, Yitao;  Lin, Ligen
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Liver Fibrosis  Hepatic Stellate Cells  Penthorum Chinense Pursh  Pinocembrin  Sma- And Mad-related Proteins  Silent Mating Type Information Regulation 2 Homolog 3  
Analysis of Genomes and Transcriptomes of Hepatocellular Carcinomas Identifies Mutations and Gene Expression Changes in the Transforming Growth Factor-β Pathway Journal article
Gastroenterology, 2018,Volume: 154,Issue: 1,Page: 195-210
Authors:  Chen J.;  Zaidi S.;  Rao S.;  Chen J.-S.;  Phan L.;  Farci P.;  Su X.;  Shetty K.;  White J.;  Zamboni F.;  Wu X.;  Rashid A.;  Pattabiraman N.;  Mazumder R.;  Horvath A.;  Wu R.-C.;  Li S.;  Xiao C.;  Deng C.-X.;  Wheeler D.A.;  Mishra B.;  Akbani R.;  Mishra L.
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Cosmic  Gene Regulation  Genetics  Immune Response  Liver Cancer  
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-β-Smad signaling pathway Journal article
Toxicology and Applied Pharmacology, 2018,Volume: 341,Page: 38
Authors:  Fayang Zhou;  Anqi Wang;  Dan li;  Yitao Wang;  Ligen Lin
Favorite  |  View/Download:7/0  |  Submit date:2018/10/31
Hepatic Stellate Cells  Liver Fibrosis  Penthorum Chinense Pursh  Pinocembrin  Silent Mating Type Information Regulation 2 Homolog 3  Sma- And Mad-related Proteins  
In situ sequestration of endogenous PDGF-BB with an ECM-mimetic sponge for accelerated wound healing Journal article
BIOMATERIALS, 2017,Volume: 148,Page: 54-68
Authors:  Li, Qiu;  Niu, Yiming;  Diao, Huajia;  Wang, Lintao;  Chen, Xiuping;  Wang, Yitao;  Dong, Lei;  Wang, Chunming
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Biomimetic Scaffolds  Extraceilular Matrix  Polysaccharides  Growth Factors  Wound Healing  
Angiotensin II induces connective tissue growth factor expression in human hepatic stellate cells by a transforming growth factor beta-independent mechanism Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Li, Ao;  Zhang, Jingyao;  Zhang, Xiaoxun;  Wang, Jun;  Wang, Songsong;  Xiao, Xiao;  Wang, Rui;  Li, Peng;  Wang, Yitao
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Arctigenin suppresses renal interstitial fibrosis in a rat model of obstructive nephropathy Journal article
PHYTOMEDICINE, 2017,Volume: 30,Page: 28-41
Authors:  Li, Ao;  Zhang, Xiaoxun;  Shu, Mao;  Wu, Mingjun;  Wang, Jun;  Zhang, Jingyao;  Wang, Rui;  Li, Peng;  Wang, Yitao
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Arctigenin  Renal Fibrosis  Inflammation  Transforming Growth Factor-beta 1  Oxidative Stress  Epithelial-mesenchymal Transition