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DNA-binding affinity and transcriptional activity of the RelA homodimer of nuclear factor B are not correlated Journal article
JOURNAL OF BIOLOGICAL CHEMISTRY, 2017,Volume: 292,Issue: 46,Page: 18821-18830
Authors:  Mulero, Maria Carmen;  Huang, De-Bin;  Thien Nguyen, H.;  Wang, Vivien Ya-Fan;  Li, Yidan;  Biswas, Tapan;  Ghosh, Gourisankar
Favorite  |  View/Download:11/0  |  Submit date:2018/10/30
cooperativity  crystal structure  dimerization  DNA transcription  NF-kB transcription factor  E-selectin  RelA  kB site  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View  |  Adobe PDF(2766Kb)  |  Favorite  |  View/Download:282/7  |  Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
RNA sequencing to determine the contribution of kinase receptor transactivation to G protein coupled receptor signalling in vascular smooth muscle cells Journal article
PLOS ONE, 2017,Volume: 12,Issue: 7
Authors:  Kamato, Danielle;  Bhaskarala, Venkata Vijayanand;  Mantri, Nitin;  Oh, Tae Gyu;  Ling, Dora;  Janke, Reearna;  Zheng, Wenhua;  Little, Peter J.;  Osman, Narin
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
The PRR11-SKA2 Bidirectional Transcription Unit Is Negatively Regulated by p53 through NF-Y in Lung Cancer Cells Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017,Volume: 18,Issue: 3
Authors:  Wang, Yitao;  Weng, Huali;  Zhang, Ying;  Long, Yinjiang;  Li, Yi;  Niu, Yulong;  Song, Fangzhou;  Bu, Youquan
Favorite  |  View/Download:4/0  |  Submit date:2018/11/01
p53  NF-Y  bidirectional promoter  PRR11  SKA2  lung cancer  
DNA-binding affinity and transcriptional activity of the RelA homodimer of nuclear factor κb are not correlated Journal article
Journal of Biological Chemistry, 2017,Volume: 292,Issue: 46,Page: 18821-18830
Authors:  Mulero M.C.;  Huang D.-B.;  Thien Nguyen H.;  Wang V.Y.-F.;  Li Y.;  Biswas T.;  Ghosh G.
Favorite  |  View/Download:4/0  |  Submit date:2019/01/15
Vascular ADAM17 as a Novel Therapeutic Target in Mediating Cardiovascular Hypertrophy and Perivascular Fibrosis Induced by Angiotensin II Journal article
Hypertension, 2016,Volume: 68,Issue: 4,Page: 949-955
Authors:  Takayanagi T.;  Forrester S.J.;  Kawai T.;  Obama T.;  Tsuji T.;  Elliott K.J.;  Nuti E.;  Rossello A.;  Kwok H.F.;  Scalia R.;  Rizzo V.;  Eguchi S.
Favorite  |  View/Download:9/0  |  Submit date:2018/12/19
End-organ Damage  Fibrosis  Hypertension  Renin Angiotensin System  Signal Transduction  
Protease activated receptor-1 mediated dual kinase receptor transactivation stimulates the expression of glycosaminoglycan synthesizing genes Journal article
Cellular Signalling, 2016,Volume: 28,Issue: 1,Page: 110-119
Authors:  Kamato D.;  Thach L.;  Getachew R.;  Burch M.;  Hollenberg M.D.;  Zheng W.;  Little P.J.;  Osman N.
Favorite  |  View/Download:1/0  |  Submit date:2018/12/21
Glycosaminoglycan enzymes  Smad linker region  Thrombin  Transactivation-dependent  Transforming growth factor β  
Integrating the GPCR transactivation-dependent and biased signalling paradigms in the context of PAR1 signalling Journal article
British Journal of Pharmacology, 2016,Volume: 173,Issue: 20,Page: 2992-3000
Authors:  Little P.J.;  Hollenberg M.D.;  Kamato D.;  Thomas W.;  Chen J.;  Wang T.;  Zheng W.;  Osman N.
Favorite  |  View/Download:14/0  |  Submit date:2018/12/21
A novel prostate cancer therapeutic strategy using icaritin-activated arylhydrocarbon-receptor to co-target androgen receptor and its splice variants Journal article
Carcinogenesis, 2015,Volume: 36,Issue: 7,Page: 757-768
Authors:  Sun F.;  Indran I.R.;  Zhang Z.W.;  Tan M.H.E.;  Li Y.;  Lim Z.L.R.;  Hua R.;  Yang C.;  Soon F.-F.;  Li J.;  Xu H.E.;  Cheung E.;  Yong E.-L.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/17
Targeting the sheddase activity of Adam17 by an Anti-ADAM17 antibody D1(A12) inhibits head and neck squamous cell carcinoma cell proliferation and motility via blockage of bradykinin induced HERs transactivation Journal article
International Journal of Biological Sciences, 2014,Volume: 10,Issue: 7,Page: 702-714
Authors:  Huang Y.;  Benaich N.;  Tape C.;  Kwok H.F.;  Murphy G.
Favorite  |  View/Download:5/0  |  Submit date:2018/12/19
Adam17  Cell Proliferation And Motility  Her Receptor And ligAnds  Inhibitory Antibody