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TNFR2-expressing CD4+ Foxp3+ regulatory T cells in cancer immunology and immunotherapy Journal article
Progress in Molecular Biology and Translational Science, 2019
Authors:  Jiang He;  Ruixin Li;  Yibo Chen;  Yuanjia Hu;  Xin Chen
Favorite  |  View/Download:7/0  |  Submit date:2019/05/08
Regulatory t Cells  Immunotherapy  Cancer  Tumor Necrosis Factor Receptor Type 2  Tumor Necrosis Factor  
Serum amyloid A promotes LPS clearance and suppresses LPS-induced inflammation and tissue injury Journal article
EMBO REPORTS, 2018,Volume: 19,Issue: 10
Authors:  Cheng, Ni;  Liang, Yurong;  Du, Xiaoping;  Ye, Richard D.
View  |  Adobe PDF(2278Kb)  |  Favorite  |  View/Download:138/3  |  Submit date:2018/10/30
acute-phase response  inflammation  innate immunity  lipopolysaccharide  serum amyloid A  
The p38 MAPK inhibitor SB203580 abrogates tumor necrosis factor-induced proliferative expansion of mouse CD4+Foxp3+ regulatory T cells Journal article
Frontiers in Immunology, 2018,Volume: 9,Issue: JUL
Authors:  He T.;  Liu S.;  Chen S.;  Ye J.;  Wu X.;  Bian Z.;  Chen X.
Favorite  |  View/Download:17/0  |  Submit date:2018/11/06
cd4+foxp3+ Regulatory t Cells  P38 Mapk  Proliferation  Tnf Receptor Type Ii  Tumor Necrosis Factor  
The p38 MaPK inhibitor sB203580 abrogates Tumor necrosis Factor-induced Proliferative expansion of Mouse cD4(+)Foxp3(+) regulatory T cells Journal article
FRONTIERS IN IMMUNOLOGY, 2018,Volume: 9
Authors:  He, Tianzhen;  Liu, Shuoyang;  Chen, Shaokui;  Ye, Jingyi;  Wu, Xueqiang;  Bian, Zhaoxiang;  Chen, Xin
Favorite  |  View/Download:10/0  |  Submit date:2018/10/30
tumor necrosis factor  TNF receptor type II  p38 MAPK  CD4(+)Foxp3(+) regulatory T cells  proliferation  
TNF Receptor Type II as an Emerging Drug Target for the Treatment of Cancer, Autoimmune Diseases, and Graft-Versus-Host Disease: Current Perspectives and In Silico Search for Small Molecule Binders Journal article
FRONTIERS IN IMMUNOLOGY, 2018,Volume: 9
Authors:  Shaikh, Faraz;  He, Jiang;  Bhadra, Pratiti;  Chen, Xin;  Siu, Shirley W., I
Favorite  |  View/Download:19/0  |  Submit date:2018/10/30
Tnf Receptor Type Ii  Tnf  Regulatory t Cells  Virtual Screening  Drug Discovery  Mm-pbsa  
TNF receptor type II as an emerging drug target for the treatment of cancer, autoimmune diseases, and graft-versus-host disease: Current perspectives and in silico search for small molecule binders Journal article
Frontiers in Immunology, 2018,Volume: 9,Issue: JUN
Authors:  Shaikh F.;  He J.;  Bhadra P.;  Chen X.;  Siu S.W.
Favorite  |  View/Download:1/0  |  Submit date:2019/04/04
Drug discovery  MM-PBSA  Regulatory T cells  TNF  TNF receptor type II  Virtual screening  
Modulation of Regulatory T Cell Activity by TNF Receptor Type II-Targeting Pharmacological Agents Journal article
FRONTIERS IN IMMUNOLOGY, 2018,Volume: 9
Authors:  Zou, Huimin;  Li, Ruixin;  Hu, Hao;  Hu, Yuanjia;  Chen, Xin
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Tnf Receptor Type Ii  Regulatory t Cells  Tnf Receptor Type Ii Agonists  Tnf Receptor Type Ii Antagonists  Immunotherapy  
Blockade of TNFR2 signaling enhances the immunotherapeutic effect of CpG ODN in a mouse model of colon cancer Journal article
SCIENCE SIGNALING, 2018,Volume: 11,Issue: 511
Authors:  Nie, Yingjie;  He, Jiang;  Shirota, Hidekazu;  Trivett, Anna L.;  Yang, De;  Klinman, Dennis M.;  Oppenheim, Joost J.;  Chen, Xin
Favorite  |  View/Download:15/0  |  Submit date:2018/10/30
Arctigenin suppresses renal interstitial fibrosis in a rat model of obstructive nephropathy Journal article
PHYTOMEDICINE, 2017,Volume: 30,Page: 28-41
Authors:  Li, Ao;  Zhang, Xiaoxun;  Shu, Mao;  Wu, Mingjun;  Wang, Jun;  Zhang, Jingyao;  Wang, Rui;  Li, Peng;  Wang, Yitao
View  |  Adobe PDF(6898Kb)  |  Favorite  |  View/Download:90/4  |  Submit date:2018/10/30
Arctigenin  Renal Fibrosis  Inflammation  Transforming Growth Factor-beta 1  Oxidative Stress  Epithelial-mesenchymal Transition  
Therapy: Paradoxical effects of targeting TNF signalling in the treatment of autoimmunity Journal article
Nature Reviews Rheumatology, 2016,Volume: 12,Issue: 11,Page: 625–626
Authors:  Xin Chen;  Joost J Oppenheim
Favorite  |  View/Download:9/0  |  Submit date:2018/11/30
Autoimmunity  Rheumatoid Arthritis  t Cells  Tumour-necrosis Factors