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Postnatal deletion of Alk5 gene in meniscal cartilage accelerates age-dependent meniscal degeneration in mice Journal article
Journal of Cellular Physiology, 2019,Volume: 234,Issue: 1,Page: 595-605
Authors:  Wang Q.;  Tan Q.;  Xu W.;  Kuang L.;  Zhang B.;  Wang Z.;  Ni Z.;  Su N.;  Jin M.;  Li C.;  Jiang W.;  Huang J.;  Li F.;  Zhu Y.;  Chen H.;  Du X.;  Chen D.;  Deng C.;  Qi H.;  Xie Y.;  Chen L.
Favorite  |  View/Download:29/0  |  Submit date:2018/12/13
Activing Receptor-like Kinases 5 (Alk5)  Matrix Degradation  Meniscal Degeneration  Transforming Growth Factor-β (Tgf-β) Signaling  
Nagilactone E suppresses TGF-beta 1-induced epithelial-mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
PHYTOMEDICINE, 2019,Volume: 52,Page: 32-39
Authors:  Le-Le Zhang;  Xiao-Ming Jiang;  Mu-Yang Huang;  Zhe-Ling Feng;  Xiuping Chen;  Yitao Wang;  Hua Li;  Ao Li;  Li-Gen Lin;  Jin-Jian Lu
Favorite  |  View/Download:15/0  |  Submit date:2020/01/09
Nagilactone e  Tgf-β1  Epithelial-mesenchymal Transitio  Smad  
CtBP promotes metastasis of breast cancer through repressing cholesterol and activating TGF-beta signaling Journal article
ONCOGENE, 2018,Volume: 38,Issue: 12,Page: 2076-2091
Authors:  Zhiqiang Zhao;  Dapeng Hao;  Li Wang;  Jingjing Li;  Yuan Meng;  Peipei Li;  Yuan Wang;  Chao Zhang;  Haisheng Zhou;  Kevin Gardner;  Li-jun Di
Favorite  |  View/Download:9/0  |  Submit date:2020/05/21
ALDH2 and the TGF-beta/SMAD3 Adaptor, Sptbn1 Suppress Hepatic Steatosis and Obesity Conference paper
Authors:  Rao, Shuyun;  Zaidi, Sobia;  Jogunoori, Wilma S.;  Gu, Shoujun;  White, Jon;  Mishra, Bibhuti;  Deng, Chu-Xia;  Latham, Patricia S.;  Mishra, Lopa
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Targeting TGF-beta Pathway E3 Ligase PJA1 in Hepatocellular Carcinoma Conference paper
Authors:  Ohshiro, Kazufumi;  Chen, Jian;  Jogunoori, Wilma S. Rani;  Deng, Chu-Xia;  Mishra, Bibhuti;  Li, Shulin;  Mishra, Lopa
Favorite  |  View/Download:24/0  |  Submit date:2018/10/30
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View  |  Adobe PDF(2621Kb)  |  Favorite  |  View/Download:599/31  |  Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
View  |  Adobe PDF(2009Kb)  |  Favorite  |  View/Download:752/64  |  Submit date:2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Generation of Smurf2 conditional knockout mice Journal article
International Journal of Biological Sciences, 2018,Volume: 14,Issue: 5,Page: 542-548
Authors:  Tang Y.;  Tang L.-Y.;  Xu X.;  Li C.;  Deng C.;  Zhang Y.E.
Favorite  |  View/Download:10/0  |  Submit date:2018/12/13
Knockout  Liver  Loxp  Mice  Smurf2  
Flavopiridol Inhibits TGF-beta-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2 Journal article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2018,Volume: 365,Issue: 1,Page: 156-164
Authors:  Rostam, Muhamad A.;  Shajimoon, Aravindra;  Kamato, Danielle;  Mitra, Partha;  Piva, Terrence J.;  Getachew, Robel;  Cao, Yingnan;  Zheng, Wenhua;  Osman, Narin;  Little, Peter J.
Favorite  |  View/Download:13/0  |  Submit date:2018/10/30
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-beta-Smad signaling pathway Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 341,Page: 38-50
Authors:  Zhou, Fayang;  Wang, Anqi;  Li, Dan;  Wang, Yitao;  Lin, Ligen
View  |  Adobe PDF(2014Kb)  |  Favorite  |  View/Download:294/16  |  Submit date:2018/10/30
Liver Fibrosis  Hepatic Stellate Cells  Penthorum Chinense Pursh  Pinocembrin  Sma- And Mad-related Proteins  Silent Mating Type Information Regulation 2 Homolog 3