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A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:  Cui, Guozhen;  Xin, Qiqi;  Tseng, Hisa Hui Ling;  Hoi, Maggie PuiMan;  Wang, Yan;  Yang, Binrui;  Choi, InLeng;  Wang, Yuqiang;  Yuan, Rong;  Chen, Keji;  Cong, Weihong;  Lee, Simon MingYuen
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Cardioprotection  Angiogenesis  ADTM  Zebrafish  VEGF  
A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of N-Methyl-D-aspartate Receptor Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Hu, Shengquan;  Hu, Huihui;  Mak, Shinghung;  Cui, Guozhen;  Lee, Mingyuen;  Shan, Luchen;  Wang, Yuqiang;  Lin, Huangquan;  Zhang, Zaijun;  Han, Yifan
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Alzheimer's disease  tetramethylpyrazine derivative  NMDA receptor  neuroprotection  oxidative stress  GSK3 beta  
Effects of tetramethylpyrazine from Chinese black vinegar on antioxidant and hypolipidemia activities in HepG2 cells Journal article
Food and Chemical Toxicology, 2017,Volume: 109,Page: 930-940
Authors:  Chen J.;  Tian J.;  Ge H.;  Liu R.;  Xiao J.
Favorite  |  View/Download:1/0  |  Submit date:2019/01/15
Anti-oxidation  Cholesterol efflux  Hypolipidemic  Liver X receptor  Peroxisome proliferator-activated receptor  Tetramethylpyrazine  
Effects of tetramethylpyrazine from Chinese black vinegar on antioxidant and hypolipidemia activities in HepG2 cells Conference paper
Authors:  Chen, Jicheng;  Tian, Jingjing;  Ge, Huifang;  Liu, Ruihai;  Xiao, Jianbo
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Tetramethylpyrazine  Hypolipidemic  Anti-oxidation  Cholesterol efflux  Liver X receptor  Peroxisome proliferator-activated receptor  
Synergistic effects of Chuanxiong-Chishao herb-pair on promoting angiogenesis at network pharmacological and pharmacodynamic levels Journal article
CHINESE JOURNAL OF INTEGRATIVE MEDICINE, 2017,Volume: 23,Issue: 9,Page: 654-662
Authors:  Wang Yan;  Guo Gang;  Yang Bin-rui;  Xin Qi-qi;  Liao Qi-wen;  Lee Simon Ming-Yuen;  Hu Yuan-jia;  Chen Ke-jj;  Cong Wei-hong
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Tetramethylpyrazine  Paeoniflorin  Angiogenesis  Network Pharmacology  
Potent Protection Against MPP+-Induced Neurotoxicity via Activating Transcription Factor MEF2D by a Novel Derivative of Naturally Occurring Danshensu/Tetramethylpyrazine Journal article
NeuroMolecular Medicine, 2016,Volume: 18,Issue: 4,Page: 561-572
Authors:  Hu S.;  Wang L.;  Mak S.;  Zhang Z.;  Xu D.;  Li H.;  Li Y.;  Hu Y.;  Lee S.M.Y.;  Wang Y.;  Han Y.
Favorite  |  View/Download:2/0  |  Submit date:2018/11/06
Danshensu/tetramethylpyrazine derivative  GSK3β  MEF2D  MPP+  Neuroprotection  Parkinson’s disease  
Tetramethylpyrazine nitrone, a multifunctional neuroprotective agent for ischemic stroke therapy Journal article
Scientific Reports, 2016,Volume: 6
Authors:  Zhang Z.;  Zhang G.;  Sun Y.;  Szeto S.S.W.;  Law H.C.H.;  Quan Q.;  Li G.;  Yu P.;  Sho E.;  Siu M.K.W.;  Lee S.M.Y.;  Chu I.K.;  Wang Y.
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Neuroprotection against glutamate-induced excitotoxicity and induction of neurite outgrowth by T-006, a novel multifunctional derivative of tetramethylpyrazine in neuronal cell models Journal article
Neurochemistry International, 2016,Volume: 99,Page: 194-205
Authors:  Xu D.;  Chen H.;  Mak S.;  Hu S.;  Tsim K.W.K.;  Hu Y.;  Sun Y.;  Zhang G.;  Wang Y.;  Zhang Z.;  Han Y.
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Alzheimer's disease  Excitotoxicity  Neurite outgrowth  Neuroprotection  Tetramethylpyrazine derivative  
A novel agent enhances the chemotherapeutic efficacy of doxorubicin in MCF-7 breast cancer cells Journal article
Frontiers in Pharmacology, 2016,Volume: 7,Issue: AUG
Authors:  Wang L.;  Chan J.Y.;  Zhou X.;  Cui G.;  Yan Z.;  Wang L.;  Yan R.;  Di L.;  Wang Y.;  Hoi M.P.;  Shan L.;  Lee S.M.
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Breast Cancer  Danshensu  Doxorubicin  Glycolysis  Grp78 Protein  Tetramethylpyrazine  
A novel agent exerts antitumor activity in breast cancer cells by targeting mitochondrial complex II Journal article
Oncotarget, 2016,Volume: 7,Issue: 22,Page: 32054-32064
Authors:  Wang L.;  Zhang X.;  Cui G.;  Chan J.Y.-W.;  Wang L.;  Li L.;  Shan L.;  Xu C.;  Zhang Q.;  Wang Y.;  Di L.;  Lee S.M.-Y.
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Breast Cancer  Danshensu  Mitochondrial Complex Ii  Reactive Oxygen Species  Tetramethylpyrazine