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γ-Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis Journal article
Toxicology and Applied Pharmacology, 2019,Volume: 363,Page: 142-153
Authors:  Wang A.;  Zhou F.;  Li D.;  Lu J.-J.;  Wang Y.;  Lin L.
Favorite  |  View/Download:8/0  |  Submit date:2018/12/28
Fibrogenesis  HMGB1  Liver fibrosis  Sirtuin 3  Superoxide  γ-Mangostin  
MnSOD mediates shear stress-promoted tumor cell migration and adhesion Journal article
FREE RADICAL BIOLOGY AND MEDICINE, 2018,Volume: 129,Page: 46-58
Authors:  Ma, Shijun;  Fu, Afu;  Lim, Sierin;  Chiew, Geraldine Giap Ying;  Luo, Kathy Qian
Favorite  |  View/Download:1/0  |  Submit date:2019/01/17
Shear stress  Tumor cell adhesion  Tumor cell migration  Reactive oxygen species  MnSOD  FAK  
A Role for MK2 in Enhancing Neutrophil-Derived ROS Production and Aggravating Liver schemia/Reperfusion Injury Journal article
FRONTIERS IN IMMUNOLOGY, 2018,Volume: 9
Authors:  Sun, Lei;  Wu, Qiong;  Nie, Yunjuan;  Cheng, Ni;  Wang, Rui;  Wang, Gang;  Zhang, Dan;  He, Huiqiong;  Ye, Richard D.;  Qian, Fang
Favorite  |  View/Download:2/0  |  Submit date:2019/01/17
MK2  ROS  p47(phox)  neutrophils  hepatic ischemia/reperfusion injury  
Serum amyloid A promotes LPS clearance and suppresses LPS-induced inflammation and tissue injury Journal article
EMBO REPORTS, 2018,Volume: 19,Issue: 10
Authors:  Cheng, Ni;  Liang, Yurong;  Du, Xiaoping;  Ye, Richard D.
View  |  Adobe PDF(2278Kb)  |  Favorite  |  View/Download:138/3  |  Submit date:2018/10/30
acute-phase response  inflammation  innate immunity  lipopolysaccharide  serum amyloid A  
Honokiol protects hepatocytes from oxidative injury through mitochondrial deacetylase SIRT3 Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 834,Page: 176-187
Authors:  Liu, Jing-Xin;  Shen, Sheng-Nan;  Tong, Qiang;  Wang, Yi-Tao;  Lin, Li-Gen
Favorite  |  View/Download:26/0  |  Submit date:2018/10/30
Honokiol  Oxidative Stress  Liver  Sirt3  Mitochondria  Fragmentation  
Neo-clerodane diterpenes and phytoecdysteroids from Ajuga decumbens Thunb. and evaluation of their effects on cytotoxic, superoxide anion generation and elastase release in vitro Journal article
FITOTERAPIA, 2018,Volume: 129,Page: 7-12
Authors:  Chen, Hao;  Tang, Ben-Qin;  Chen, Li;  Liang, Jing-Yu;  Sun, Jian-Bo
Favorite  |  View/Download:8/0  |  Submit date:2018/10/30
Ajuga decumbens  Neoclerodane diterpenoids  Phytoecdysterone  Cytotoxic activities  Superoxide anion generation  Elastase release  
A reciprocal relationship between reactive oxygen species and mitochondrial dynamics in neurodegeneration Journal article
REDOX BIOLOGY, 2018,Volume: 14,Page: 7-19
Authors:  Hung, Clara Hiu-Ling;  Cheng, Sally Shuk-Yee;  Cheung, Yuen-Ting;  Wuwongse, Suthicha;  Zhang, Natalie Qishan;  Ho, Yuen-Shan;  Lee, Simon Ming-Yuen;  Chang, Raymond Chuen-Chung
Favorite  |  View/Download:14/0  |  Submit date:2018/10/30
Alzheimer's disease  beta-amyloid  Mitochondria  Fission and fusion  Drp-1  Neurodegeneration  
Toxic Reactive Oxygen Species Enhanced Synergistic Combination Therapy by Self-Assembled Metal-Phenolic Network Nanoparticles Journal article
Advanced Materials, 2018,Volume: 30,Issue: 8
Authors:  Dai Y.;  Yang Z.;  Cheng S.;  Wang Z.;  Zhang R.;  Zhu G.;  Wang Z.;  Yung B.C.;  Tian R.;  Jacobson O.;  Xu C.;  Ni Q.;  Song J.;  Sun X.;  Niu G.;  Chen X.
Favorite  |  View/Download:4/0  |  Submit date:2019/01/15
Combination Therapy  Metal-polyphenol Networks  Positron Emission Tomography  Reactive Oxygen Species  Self-assembly  
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-beta-Smad signaling pathway Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 341,Page: 38-50
Authors:  Zhou, Fayang;  Wang, Anqi;  Li, Dan;  Wang, Yitao;  Lin, Ligen
View  |  Adobe PDF(2014Kb)  |  Favorite  |  View/Download:100/7  |  Submit date:2018/10/30
Liver Fibrosis  Hepatic Stellate Cells  Penthorum Chinense Pursh  Pinocembrin  Sma- And Mad-related Proteins  Silent Mating Type Information Regulation 2 Homolog 3  
gamma-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 40,Page: 544-553
Authors:  Wang, Anqi;  Li, Dan;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Lin, Ligen
View  |  Adobe PDF(1410Kb)  |  Favorite  |  View/Download:101/2  |  Submit date:2018/10/30
Gamma-mangostin  Mangosteen  Liver Oxidative Injury  Nrf2  Sirt1  Pgc-1 Alpha