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An Integrated Transfer Learning and Multitask Learning Approach for Pharmacokinetic Parameter Prediction Journal article
Molecular Pharmaceutics, 2019,Volume: 16,Issue: 2,Page: 533-541
Authors:  Ye Z.;  Yang Y.;  Li X.;  Cao D.;  Ouyang D.
Favorite  |  View/Download:7/0  |  Submit date:2019/02/14
ADME  deep learning  multitask learning  pharmacokinetic parameters  transfer learning  
Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships Journal article
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018,Volume: 28,Issue: 21,Page: 3441-3445
Authors:  Zhang, Shao-Lin;  Yang, Zheng;  Hu, Xiaohui;  Tam, Kin Yip
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Pyruvate dehydrogenase kinase  Pyruvate dehydrogenase complex  Antiproliferative activity  Dichloroacetophenone  Kinase inhibition  
Serum amyloid A promotes LPS clearance and suppresses LPS-induced inflammation and tissue injury Journal article
EMBO REPORTS, 2018,Volume: 19,Issue: 10
Authors:  Cheng, Ni;  Liang, Yurong;  Du, Xiaoping;  Ye, Richard D.
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acute-phase response  inflammation  innate immunity  lipopolysaccharide  serum amyloid A  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
View  |  Adobe PDF(2009Kb)  |  Favorite  |  View/Download:255/37  |  Submit date:2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Synthetic Study toward the Total Synthesis of Taxezopidines A and B Journal article
ORGANIC LETTERS, 2018,Volume: 20,Issue: 18,Page: 5905-5909
Authors:  Hu, Ya-Jian;  Fan, Jian-Hong;  Li, Shaoping;  Zhao, Jing;  Li, Chuang-Chuang
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Evidence and prospective of plant derived flavonoids as antiplatelet agents: Strong candidates to be drugs of future Conference paper
Authors:  Khan, Harron;  Jawad, Mohammad;  Kamal, Mohammad Amjad;  Baldi, Alessandra;  Xiao, Jianbo;  Nabavi, Seyed Mohammad;  Daglia, Maria
Favorite  |  View/Download:10/0  |  Submit date:2018/10/30
Antiplatelet  Preclinical studies  Structure-activity relationship (SAR) studies  Pharmacokinetic parameters  Safety profile  
Evidence and prospective of plant derived flavonoids as antiplatelet agents: Strong candidates to be drugs of future Journal article
Food and Chemical Toxicology, 2018,Volume: 119,Page: 355-367
Authors:  Khan H.;  Jawad M.;  Kamal M.A.;  Baldi A.;  Xiao J.;  Nabavi S.M.;  Daglia M.
Favorite  |  View/Download:2/0  |  Submit date:2019/01/15
Antiplatelet  Pharmacokinetic parameters  Preclinical studies  Safety profile  Structure-activity relationship (SAR) studies  
Periplaneta americana Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Rats by Keap1/Nrf-2 Activation, Intestinal Barrier Function, and Gut Microbiota Regulation Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Ma, Xuewei;  Hu, Yichen;  Li, Xin;  Zheng, Xiaoting;  Wang, Yitao;  Zhang, Jinming;  Fu, Chaomei;  Geng, Funeng
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Ulcerative Colitis  Periplaneta Americana  16s Rrna  Gut Microbiota  Intestinal Immunity  
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:  Cui, Guozhen;  Xin, Qiqi;  Tseng, Hisa Hui Ling;  Hoi, Maggie PuiMan;  Wang, Yan;  Yang, Binrui;  Choi, InLeng;  Wang, Yuqiang;  Yuan, Rong;  Chen, Keji;  Cong, Weihong;  Lee, Simon MingYuen
View  |  Adobe PDF(3018Kb)  |  Favorite  |  View/Download:85/3  |  Submit date:2018/10/30
Cardioprotection  Angiogenesis  ADTM  Zebrafish  VEGF  
Water soluble fraction from ethanolic extract of Clausena lansium seeds alleviates obesity and insulin resistance, and changes the composition of gut microbiota in high-fat diet-fed mice Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 47,Page: 192-199
Authors:  Shen, Shengnan;  Liao, Qiwen;  Huang, Li;  Li, Dan;  Zhang, Qingwen;  Wang, Yitao;  Lee, Simon Ming-Yuen;  Lin, Ligen
View  |  Adobe PDF(1563Kb)  |  Favorite  |  View/Download:143/21  |  Submit date:2018/10/30
Clausena Lansium  Fat Mass Gain  Insulin Sensitivity  Gut Microbiota  Wampee