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Diethyl blechnic, a novel natural product isolated from salvia miltiorrhiza bunge, inhibits doxorubicin-induced apoptosis by inhibiting ROS and activating JNK1/2 Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 6
Authors:  Yu J.;  Gao H.;  Wu C.;  Xu Q.-M.;  Lu J.-J.;  Chen X.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/28
Cardiotoxicity  Diethyl Blechnic  Dox  Jnk1/2  Ros  
2-methoxy-6-acetyl-7-methyljuglone (MAM) induces iNOS/NO-mediated DNA damage response through activation of MAPKs pathways Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 6,Page: 903-913
Authors:  Niu Y.;  Yuan R.;  Gao H.;  Lu J.-J.;  Kong Q.;  Chen X.
Favorite  |  View/Download:6/0  |  Submit date:2018/12/28
Atm/chk2  Dna Damage  Inos/no  L-arginine  Mam  Mapks  
Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells Journal article
FREE RADICAL BIOLOGY AND MEDICINE, 2017,Volume: 108,Page: 433-444
Authors:  Sun, Wen;  Wu, Xiaxia;  Gao, Hongwei;  Yu, Jie;  Zhao, Wenwen;  Lu, Jin-Jian;  Wang, Jinhua;  Du, Guanhua;  Chen, Xiuping
Favorite  |  View/Download:11/0  |  Submit date:2018/10/30
Necroptosis  C-jun N-terminal Kinase  Calcium  Ros  
Norditerpenoids and Dinorditerpenoids from the Seeds of Podocarpus nagi as Cytotoxic Agents and Autophagy Inducers Journal article
JOURNAL OF NATURAL PRODUCTS, 2017,Volume: 80,Issue: 7,Page: 2110-2117
Authors:  Feng, Zhe-Ling;  Zhang, Le-Le;  Zheng, Yuan-Dong;  Liu, Qian-Yu;  Liu, Jing-Xin;  Feng, Lu;  Huang, Li;  Zhang, Qing-Wen;  Lu, Jin-Jian;  Lin, Li-Gen
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Polyphyllin VII Induces an Autophagic Cell Death by Activation of the JNK Pathway and Inhibition of PI3K/AKT/mTOR Pathway in HepG2 Cells Journal article
PloS one, 2016,Volume: 11,Issue: 1,Page: e0147405
Authors:  Zhang C.;  Jia X.;  Wang K.;  Bao J.;  Li P.;  Chen M.;  Wan J.-B.;  Su H.;  Mei Z.;  He C.
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Synergistic chemopreventive effects of curcumin and berberine on human breast cancer cells through induction of apoptosis and autophagic cell death Journal article
Scientific Reports, 2016,Volume: 6
Authors:  Wang K.;  Zhang C.;  Bao J.;  Jia X.;  Liang Y.;  Wang X.;  Chen M.;  Su H.;  Li P.;  Wan J.-B.;  He C.
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Cryptotanshinone induces pro-death autophagy through JNK signaling mediated by reactive oxygen species generation in lung cancer cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2016,Volume: 16,Issue: 5,Page: 593
Authors:  Hao W.;  Zhang X.;  Zhao W.;  Zhu H.;  Liu Z.-Y.;  Lu J.;  Chen X.
Favorite  |  View/Download:2/0  |  Submit date:2018/10/30
Autophagy  Cancer  Cryptotanshinone  Jnk  Reactive Oxygen Species  
Platycodin D induces apoptosis and triggers ERK- and JNK-mediated autophagy in human hepatocellular carcinoma BEL-7402 cells Journal article
Acta Pharmacologica Sinica, 2015,Volume: 36,Issue: 12,Page: 1503
Authors:  Li T.;  Xu X.-H.;  Tang Z.-H.;  Wang Y.-F.;  Leung C.-H.;  Ma D.-L.;  Chen X.-P.;  Wang Y.-T.;  Chen Y.;  Lu J.-J.
Favorite  |  View/Download:4/0  |  Submit date:2018/10/31
Apoptosis  Autophagy  Erk  Baf  Bel-7402 Cells  Chloroquine  Human Hepatocellular Carcinoma  Jnk  Platycodin d  Sp600125  U0126  
Glycyrrhetinic acid induces cytoprotective autophagy via the inositol-requiring enzyme 1α-c-Jun N-terminal kinase cascade in non-small cell lung cancer cells Journal article
Oncotarget, 2015,Volume: 6,Issue: 41,Page: 43911
Authors:  Tang Z.-H.;  Zhang L.-L.;  Li T.;  Lu J.-H.;  Ma D.-L.;  Leung C.-H.;  Chen X.-P.;  Jiang H.-L.;  Wang Y.-T.;  Lu J.-J.
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Autophagy  Glycyrrhetinic Acid  Ire1α  Jnk  Protective  
Ox-LDL-induced LOX-1 expression in vascular smooth muscle cells: Role of reactive oxygen species Journal article
Fundamental and Clinical Pharmacology, 2011,Volume: 25,Issue: 5,Page: 572
Authors:  Sun Y.;  Chen X.
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Lectin-like Oxidized Low Density Lipoprotein Receptor-1  Oxidized Low Density Lipoprotein  Reactive Oxygen Species  Vascular Smooth Muscle Cells