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Flavopiridol inhibits TGF-b-stimulated biglycan synthesis by blocking linker region phosphorylation and nuclear translocation of Smad2 Journal article
Journal of Pharmacology and Experimental Therapeutics, 2018,Volume: 365,Issue: 1,Page: 156-164
Authors:  Rostam M.A.;  Shajimoon A.;  Kamato D.;  Mitra P.;  Piva T.J.;  Getachew R.;  Cao Y.;  Zheng W.;  Osman N.;  Little P.J.
Favorite | View/Download:7/0 | TC[WOS]:16 TC[Scopus]:15 | Submit date:2018/12/21
Flavopiridol Inhibits TGF-beta-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2 Journal article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2018,Volume: 365,Issue: 1,Page: 156-164
Authors:  Rostam, Muhamad A.;  Shajimoon, Aravindra;  Kamato, Danielle;  Mitra, Partha;  Piva, Terrence J.;  Getachew, Robel;  Cao, Yingnan;  Zheng, Wenhua;  Osman, Narin;  Little, Peter J.
Favorite | View/Download:22/0 | TC[WOS]:16 TC[Scopus]:15 | Submit date:2018/10/30
Pinocembrin from Penthorum chinense Pursh suppresses hepatic stellate cells activation through a unified SIRT3-TGF-beta-Smad signaling pathway Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 341,Page: 38-50
Authors:  Zhou, Fayang;  Wang, Anqi;  Li, Dan;  Wang, Yitao;  Lin, Ligen
View | Adobe PDF | Favorite | View/Download:536/23 | TC[WOS]:16 TC[Scopus]:16 | Submit date:2018/10/30
Liver Fibrosis  Hepatic Stellate Cells  Penthorum Chinense Pursh  Pinocembrin  Sma- And Mad-related Proteins  Silent Mating Type Information Regulation 2 Homolog 3  
The role of specific Smad linker region phosphorylation in TGF-beta mediated expression of glycosaminoglycan synthesizing enzymes in vascular smooth muscle Journal article
CELLULAR SIGNALLING, 2016,Volume: 28,Issue: 8,Page: 956-966
Authors:  Muhamad A. Rostam;  Danielle Kamato;  Terence J. Piva;  Wenhua Zheng;  Peter J. Little;  Narin Osman
Favorite | View/Download:10/0 | TC[WOS]:23 TC[Scopus]:26 | Submit date:2020/06/11
Transforming Growth Factor-beta  Glycosaminoglycan  Atherosclerosis  Vascular Smooth Muscle  Signalling  Smad  
The role of specific Smad linker region phosphorylation in TGF-β mediated expression of glycosaminoglycan synthesizing enzymes in vascular smooth muscle Journal article
Cellular Signalling, 2016,Volume: 28,Issue: 8,Page: 956
Authors:  Rostam M.A.;  Kamato D.;  Piva T.J.;  Zheng W.;  Little P.J.;  Osman N.
Favorite | View/Download:6/0 | TC[WOS]:23 TC[Scopus]:26 | Submit date:2018/10/30
Atherosclerosis  Glycosaminoglycan  Signalling  Smad  Transforming growth factor-β  Vascular smooth muscle  
Protease activated receptor-1 mediated dual kinase receptor transactivation stimulates the expression of glycosaminoglycan synthesizing genes Journal article
Cellular Signalling, 2016,Volume: 28,Issue: 1,Page: 110-119
Authors:  Kamato D.;  Thach L.;  Getachew R.;  Burch M.;  Hollenberg M.D.;  Zheng W.;  Little P.J.;  Osman N.
Favorite | View/Download:6/0 | TC[WOS]:23 TC[Scopus]:23 | Submit date:2018/12/21
Glycosaminoglycan enzymes  Smad linker region  Thrombin  Transactivation-dependent  Transforming growth factor β  
Transforming growth factor β-mediated site-specific Smad linker region phosphorylation in vascular endothelial cells Journal article
The Journal of pharmacy and pharmacology, 2014,Volume: 66,Issue: 12,Page: 1722-1733
Authors:  Kamato D.;  Rostam M.A.;  Piva T.J.;  Babaahmadi Rezaei H.;  Getachew R.;  Thach L.;  Bernard R.;  Zheng W.;  Little P.J.;  Osman N.
Favorite | View/Download:11/0 | TC[WOS]:20 TC[Scopus]:21 | Submit date:2018/12/21
cell signalling  serine/threonine kinase  Smad linker region  Smads  transforming growth factor-β  
(S)-[6]-Gingerol inhibits TGF-β-stimulated biglycan synthesis but not glycosaminoglycan hyperelongation in human vascular smooth muscle cells Journal article
Journal of Pharmacy and Pharmacology, 2013,Volume: 65,Issue: 7,Page: 1026-1036
Authors:  Kamato D.;  Babaahmadi Rezaei H.;  Getachew R.;  Thach L.;  Guidone D.;  Osman N.;  Roufogalis B.;  Duke C.C.;  Tran V.H.;  Zheng W.;  Little P.J.
Favorite | View/Download:7/0 | TC[WOS]:23 TC[Scopus]:22 | Submit date:2018/12/21
(S)-[6]-Gingerol  biglycan  proteoglycans  Smad signalling  
Forkhead box protein O, a family of transcription factors integrating diverse biological functions Journal article
CELLULAR AND MOLECULAR LIFE SCIENCES, 2011,Volume: 68,Issue: 1,Page: 97-107
Authors:  Burch, ML;  Zheng, WH;  Little, PJ
Favorite | View/Download:16/0 | TC[WOS]:47 TC[Scopus]:45 | Submit date:2019/01/10
Transforming Growth Factor-beta  Phosphorylation  Signalling  Vascular Smooth Muscle  Collagen  Proteoglycans  Smads  
Smad linker region phosphorylation in the regulation of extracellular matrix synthesis Journal article
CELLULAR AND MOLECULAR LIFE SCIENCES, 2011,Volume: 68,Issue: 1,Page: 97-107
Authors:  Burch, ML;  Zheng, WH;  Little, PJ
Favorite | View/Download:7/0 | TC[WOS]:47 TC[Scopus]:45 | Submit date:2019/01/10
Transforming Growth Factor-beta  Phosphorylation  Signalling  Vascular Smooth Muscle  Collagen  Proteoglycans  Smads