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γ-Mangostin alleviates liver fibrosis through Sirtuin 3-superoxide-high mobility group box 1 signaling axis Journal article
Toxicology and Applied Pharmacology, 2019,Volume: 363,Page: 142-153
Authors:  Wang A.;  Zhou F.;  Li D.;  Lu J.-J.;  Wang Y.;  Lin L.
Favorite  |  View/Download:8/0  |  Submit date:2018/12/28
Fibrogenesis  HMGB1  Liver fibrosis  Sirtuin 3  Superoxide  γ-Mangostin  
Resveratrol ameliorates endothelial dysfunction in diabetic and obese mice through sirtuin 1 and peroxisome proliferator-activated receptor δ Journal article
Pharmacological Research, 2019,Volume: 139,Page: 384-394
Authors:  Cheang W.S.;  Wong W.T.;  Wang L.;  Cheng C.K.;  Lau C.W.;  Ma R.C.W.;  Xu A.;  Wang N.;  Huang Y.;  Tian X.Y.
Favorite  |  View/Download:3/0  |  Submit date:2019/01/15
Diet induced obesity  Endothelial dysfunction  PPARδ  SIRT1  
Nicotinamide Promotes Cell Survival and Differentiation as Kinase Inhibitor in Human Pluripotent Stem Cells Journal article
Stem Cell Reports, 2018,Volume: 11,Issue: 6,Page: 1347-1356
Authors:  Meng Y.;  Ren Z.;  Xu F.;  Zhou X.;  Song C.;  Wang V.Y.-F.;  Liu W.;  Lu L.;  Thomson J.A.;  Chen G.
Favorite  |  View/Download:1/0  |  Submit date:2019/01/15
cell differentiation  cell survival  human pluripotent stem cell  kinase inhibitor  nicotinamide  
1,3,6,7-Tetrahydroxy-8-prenylxanthone ameliorates inflammatory responses resulting from the paracrine interaction of adipocytes and macrophages Journal article
BRITISH JOURNAL OF PHARMACOLOGY, 2018,Volume: 175,Issue: 10,Page: 1590-1606
Authors:  Li, Dan;  Liu, Qianyu;  Sun, Wen;  Chen, Xiuping;  Wang, Ying;  Sun, Yuxiang;  Lin, Ligen
Favorite  |  View/Download:11/0  |  Submit date:2018/10/30
gamma-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 40,Page: 544-553
Authors:  Wang, Anqi;  Li, Dan;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Lin, Ligen
View  |  Adobe PDF(1410Kb)  |  Favorite  |  View/Download:104/4  |  Submit date:2018/10/30
Gamma-mangostin  Mangosteen  Liver Oxidative Injury  Nrf2  Sirt1  Pgc-1 Alpha  
Analysis of Genomes and Transcriptomes of Hepatocellular Carcinomas Identifies Mutations and Gene Expression Changes in the Transforming Growth Factor-β Pathway Journal article
Gastroenterology, 2018,Volume: 154,Issue: 1,Page: 195-210
Authors:  Chen J.;  Zaidi S.;  Rao S.;  Chen J.-S.;  Phan L.;  Farci P.;  Su X.;  Shetty K.;  White J.;  Zamboni F.;  Wu X.;  Rashid A.;  Pattabiraman N.;  Mazumder R.;  Horvath A.;  Wu R.-C.;  Li S.;  Xiao C.;  Deng C.-X.;  Wheeler D.A.;  Mishra B.;  Akbani R.;  Mishra L.
Favorite  |  View/Download:8/0  |  Submit date:2018/12/13
Cosmic  Gene Regulation  Genetics  Immune Response  Liver Cancer  
SIRT6 Is Essential for Adipocyte Differentiation by Regulating Mitotic Clonal Expansion Journal article
CELL REPORTS, 2017,Volume: 18,Issue: 13,Page: 3155-3166
Authors:  Chen, Qiang;  Hao, Wenhui;  Xiao, Cuiying;  Wang, Ruihong;  Xu, Xiaoling;  Lu, Huiyan;  Chen, Weiping;  Deng, Chu-Xia
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Emerging roles of SIRT1 in fatty liver diseases Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2017,Volume: 13,Issue: 7,Page: 852-867
Authors:  Ding, Ren-Bo;  Bao, Jiaolin;  Deng, Chu-Xia
Favorite  |  View/Download:17/0  |  Submit date:2018/10/30
Fatty Liver Diseases  Lipogenesis  Fatty Acid Beta-oxidation  Oxidative Stress  Inflammation  
Negative reciprocal regulation between Sirt1 and Per2 modulates the circadian clock and aging Journal article
Scientific Reports, 2016,Volume: 6
Authors:  Wang R.-H.;  Zhao T.;  Cui K.;  Hu G.;  Chen Q.;  Chen W.;  Wang X.-W.;  Soto-Gutierrez A.;  Zhao K.;  Deng C.-X.
Favorite  |  View/Download:7/0  |  Submit date:2018/12/13
Ligand-based virtual screening and inductive learning for identification of SIRT1 inhibitors in natural products Journal article
Scientific Reports, 2016,Volume: 6
Authors:  Sun Y.;  Zhou H.;  Zhu H.;  Leung S.-W.
Favorite  |  View/Download:1/0  |  Submit date:2019/01/15