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Resveratrol ameliorates endothelial dysfunction in diabetic and obese mice through sirtuin 1 and peroxisome proliferator-activated receptor δ Journal article
Pharmacological Research, 2019,Volume: 139,Page: 384-394
Authors:  Cheang W.S.;  Wong W.T.;  Wang L.;  Cheng C.K.;  Lau C.W.;  Ma R.C.W.;  Xu A.;  Wang N.;  Huang Y.;  Tian X.Y.
Favorite  |  View/Download:2/0  |  Submit date:2019/01/15
Diet induced obesity  Endothelial dysfunction  PPARδ  SIRT1  
BRCA1 function in the intra-S checkpoint is activated by acetylation via a pCAF/SIRT1 axis Journal article
ONCOGENE, 2018,Volume: 37,Issue: 17,Page: 2343-2350
Authors:  Lahusen, Tyler J.;  Kim, Seung-Jin;  Miao, Kai;  Huang, Zebin;  Xu, Xiaoling;  Deng, Chu-Xia
Favorite  |  View/Download:18/0  |  Submit date:2018/10/30
γ-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction Journal article
Journal of Functional Foods, 2018,Volume: 40,Page: 544-553
Authors:  Wang A.;  Li D.;  Wang S.;  Zhou F.;  Li P.;  Wang Y.;  Lin L.
Favorite  |  View/Download:7/0  |  Submit date:2018/10/31
Γ-mangostin  Mangosteen  Liver Oxidative Injury  Nrf2  Sirt1  Pgc-1α  
gamma-Mangostin, a xanthone from mangosteen, attenuates oxidative injury in liver via NRF2 and SIRT1 induction Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 40,Page: 544-553
Authors:  Wang, Anqi;  Li, Dan;  Wang, Shengpeng;  Zhou, Fayang;  Li, Peng;  Wang, Yitao;  Lin, Ligen
View  |  Adobe PDF(1410Kb)  |  Favorite  |  View/Download:92/2  |  Submit date:2018/10/30
Gamma-mangostin  Mangosteen  Liver Oxidative Injury  Nrf2  Sirt1  Pgc-1 Alpha  
Hormetic effect of panaxatriol saponins confers neuroprotection in PC12 cells and zebrafish through PI3K/AKT/mTOR and AMPK/SIRT1/FOXO3 pathways Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Zhang, Chao;  Li, Chuwen;  Chen, Shenghui;  Li, Zhiping;  Ma, Lijuan;  Jia, Xuejing;  Wang, Kai;  Bao, Jiaolin;  Liang, Yeer;  Chen, Meiwan;  Li, Peng;  Su, Huanxing;  Lee, Simon Ming Yuen;  Liu, Kechun;  Wan, Jian-Bo;  He, Chengwei
Favorite  |  View/Download:11/0  |  Submit date:2018/10/30
Emerging roles of SIRT1 in fatty liver diseases Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2017,Volume: 13,Issue: 7,Page: 852-867
Authors:  Ding, Ren-Bo;  Bao, Jiaolin;  Deng, Chu-Xia
Favorite  |  View/Download:16/0  |  Submit date:2018/10/30
Fatty Liver Diseases  Lipogenesis  Fatty Acid Beta-oxidation  Oxidative Stress  Inflammation  
Negative reciprocal regulation between Sirt1 and Per2 modulates the circadian clock and aging Journal article
Scientific Reports, 2016,Volume: 6
Authors:  Wang R.-H.;  Zhao T.;  Cui K.;  Hu G.;  Chen Q.;  Chen W.;  Wang X.-W.;  Soto-Gutierrez A.;  Zhao K.;  Deng C.-X.
Favorite  |  View/Download:7/0  |  Submit date:2018/12/13
SIRT1 disruption in human fetal hepatocytes leads to increased accumulation of glucose and lipids Journal article
PLoS ONE, 2016,Volume: 11,Issue: 2
Authors:  Tobita T.;  Guzman-Lepe J.;  Takeishi K.;  Nakao T.;  Wang Y.;  Meng F.;  Deng C.-X.;  De L'Hortet A.C.;  Soto-Gutierrez A.
Favorite  |  View/Download:3/0  |  Submit date:2018/12/13
Ligand-based virtual screening and inductive learning for identification of SIRT1 inhibitors in natural products Journal article
Scientific Reports, 2016,Volume: 6
Authors:  Sun Y.;  Zhou H.;  Zhu H.;  Leung S.-W.
Favorite  |  View/Download:1/0  |  Submit date:2019/01/15
SIRT1 deacetylates TopBP1 and modulates intra-sphase checkpoint and DNA replication origin firing Journal article
International Journal of Biological Sciences, 2014,Volume: 10,Issue: 10,Page: 1193-1202
Authors:  Wang R.-H.;  Lahusen T.J.;  Chen Q.;  Xu X.;  Miller Jenkins L.M.;  Leo E.;  Fu H.;  Aladjem M.;  Pommier Y.;  Appella E.;  Deng C.-X.
Favorite  |  View/Download:7/0  |  Submit date:2018/12/13
Dna Replication Fork  Genetic Stability  Intra-s-phase Checkpoint  Sirt1  Topbp1