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Stagewise keratinocyte differentiation from human embryonic stem cells by defined signal transduction modulators Journal article
International Journal of Biological Sciences, 2020,Volume: 16,Issue: 8,Page: 1450-1462
Authors:  Zhong,Hui;  Ren,Zhili;  Wang,Xiaoyan;  Miao,Kai;  Ni,Wenjun;  Meng,Ya;  Lu,Ligong;  Wang,Chunming;  Liu,Weiwei;  Deng,Chu Xia;  Xu,Ren He;  Chen,Guokai
Favorite | View/Download:72/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/09/16
Defined factors  Human embryonic stem cells  Keratinocyte differentiation  
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 10,Page: 1279-1291
Authors:  Lei Fan;  Xiao-xia Qiu;  Zhi-yuan Zhu;  Jian-lu Lv;  Jian Lu;  Fei Mao;  Jin Zhu;  Jia-ying Wang;  Xiao-wei Guan;  Jing Chen;  Jin Ren;  Ji-ming Ye;  Yong-hua Zhao;  Jian Li;  Xu Shen
Favorite | View/Download:23/0 | TC[WOS]:2 TC[Scopus]:8 | Submit date:2020/04/14
App/ps1 Transgenic Mice  Alzheimer’s Disease  Autophagy  Inflammation  Nitazoxanide  
Deciphering the Pharmacological Mechanisms of the Huayu-Qiangshen-Tongbi Formula Through Integrating Network Pharmacology and In Vitro Pharmacological Investigation Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Zihao Wang;  Ke-Gang Linghu;  Yuanjia Hu;  Huali Zuo;  Hao Yi;  Shi-Hang Xiong;  Jinjian Lu;  Ging Chan;  Hua Yu;  Run-Yue Huang
Favorite | View/Download:31/0 | TC[WOS]:1 TC[Scopus]:4 | Submit date:2019/12/04
Rheumatoid Arthritis  Network Pharmacology  Traditional Chinese Medicine  Huayu-qiangshen-tongbi Formula  In Vitro Validation  
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 9,Page: 1193-1204
Authors:  Ting-ting Zhou;  Tong Zhao;  Fei Ma;  Yi-nan Zhang;  Jing Jiang;  Yuan Ruan;  Qiu-ying Yan;  Gai-hong Wang;  Jin Ren;  Xiao-wei Guan;  Jun Guo;  Yong-hua Zhao;  Ji-ming Ye;  Li-hong Hu;  Jing Chen;  Xu Shen
Favorite | View/Download:13/0 | TC[WOS]:1 TC[Scopus]:1 | Submit date:2020/04/14
Type 2 Diabetes Mellitus  Hepatic Gluconeogenesis  Ampk Signaling Pathway  (e)-3-(2-(Quinoline-4-yl)Vinyl)-1h-indol-6-ol (Qvo)  4-[2-(1h-indol-3-yl)Vinyl]Quinoline (Ivq)  Prodrug  
Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells Journal article
STEM CELL REPORTS, 2019,Volume: 13,Issue: 2,Page: 338-351
Authors:  Chengcheng Song;  Faxiang Xu;  Zhili Ren;  Yumeng Zhang;  Ya Meng;  Yiqi Yang;  Shreyas Lingadahalli;  Edwin Cheung;  Gang Li;  Weiwei Liu;  Jianbo Wan;  Yang Zhao;  Guokai Chen
Favorite | View/Download:25/0 | TC[WOS]:1 TC[Scopus]:5 | Submit date:2020/04/22
Hescs  Pyruvate  Bmp4  Glycolysis  Tca Cycle  Ampk  Wnt  Metabolism  Mesoderm  Differentiation  
Yinchenhao decoction suppresses rat liverfibrosis involved in an apoptosisregulation mechanism based on network pharmacology and transcriptomicanalysis Journal article
Biomedicine & Pharmacotherapy, 2019,Volume: 114
Authors:  Fei-Fei Cai;  Yan-Qin Bian;  Rong Wu;  Yang Sun;  Xiao-Le Chen;  Meng-Die Yang;  Qian-ru Zhang;  Yuanjia Hu;  Ming-Yu Sun;  Shi-Bing Su
Favorite | View/Download:11/0 | TC[WOS]:17 TC[Scopus]:19 | Submit date:2020/10/23
Yinchenhao Decoction  Liver Fibrosis  Network Pharmacology  Transcriptomics  Apoptosis  
Neuroprotective Effects of BHDPC, a Novel Neuroprotectant, on Experimental Stroke by Modulating Microglia Polarization Journal article
ACS CHEMICAL NEUROSCIENCE, 2019,Volume: 10,Issue: 5,Page: 2434-2449
Authors:  Chuwen Li;  Yaqi Bian;  Yu Feng;  Fan Tang;  Liang Wang;  Maggie Pui Man Hoi;  Dan Ma;  Chao Zhao;  Simon Ming Yuen Lee
Favorite | View/Download:231/0 | TC[WOS]:4 TC[Scopus]:9 | Submit date:2020/01/16
Bhdpc  Ischemic Stroke  Microglia  Nf-κb  Creb  Pka  
A combination of Pueraria lobata and Silybum marianum protects against alcoholic liver disease in mice Journal article
PHYTOMEDICINE, 2019,Volume: 58
Authors:  Feng Ruibing;  Chen Jie-Hua;  Liu Cong-Hui;  Xia Fang-Bo;  Xiao Zeyu;  hang Xuguang;  Wan Jian-Bo
Favorite | View/Download:19/0 | TC[WOS]:3 TC[Scopus]:9 | Submit date:2020/04/22
SiL.bum Marianum(L.)Gaerth  Pueraria Lobata(Wild.)Ohwi  Alcoholic Liver Disease  Hepatic Inflammation  Intestinal Barrier Dysfunction  
Upregulation of phosphoserine phosphatase contributes to tumor progression and predicts poor prognosis in non-small cell lung cancer patients Journal article
THORACIC CANCER, 2019,Volume: 10,Issue: 5,Page: 1203-1212
Authors:  Li Liao;  Huajian Yu;  Mengxi Ge;  Qiong Zhan;  Ruofan Huang;  Xiaoyu Ji;  Xiaohua Liang;  Xinli Zhou
Favorite | View/Download:20/0 | TC[WOS]:0 TC[Scopus]:2 | Submit date:2020/03/10
Akt/ampk Signaling Pathway  Metastasis  Nsclc  Proliferation  Psph  
Angiotensin II promotes ovarian cancer spheroid formation and metastasis by upregulation of lipid desaturation and suppression of endoplasmic reticulum stress Journal article
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2019,Volume: 38
Authors:  Qingyu Zhang;  Shan Yu;  Melody Man Ting Lam;  Terence Chuen Wai Poon;  Litao Sun;  Yufei Jiao;  Alice Sze Tsai Wong;  Leo Tsz On Lee
Favorite | View/Download:19/0 | TC[WOS]:1 TC[Scopus]:7 | Submit date:2020/05/15
Angiotensin Ii  Ovarian Cancer  Spheroid Formation  Lipogenesis  Endoplasmic Reticulum Stress