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Schisantherin A Attenuates Neuroinflammation in Activated Microglia: Role of Nrf2 Activation Through ERK Phosphorylation Journal article
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018,Volume: 47,Issue: 5,Page: 1769-1784
Authors:  Li, Chuwen;  Chen, Tongkai;  Zhou, Hefeng;  Zhang, Chao;  Feng, Yu;  Tang, Fan;  Hoi, Maggie Pui-Man;  He, Chengwei;  Zheng, Ying;  Lee, Simon Ming-Yuen
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Schisantherin a  Neuroinflammation  Microglia  Nrf2  Nf-kappa b  
Small-Sized mPEG-PLGA Nanoparticles of Schisantherin A with Sustained Release for Enhanced Brain Uptake and Anti-Parkinsonian Activity Journal article
ACS Applied Materials and Interfaces, 2017,Volume: 9,Issue: 11,Page: 9516-9527
Authors:  Chen T.;  Li C.;  Li Y.;  Yi X.;  Wang R.;  Lee S.M.-Y.;  Zheng Y.
Favorite | View/Download:6/0 | TC[WOS]:21 TC[Scopus]:29 | Submit date:2018/12/28
brain delivery  cellular uptake  fluorescence resonance energy transfer (FRET)  mPEG−PLGA nanoparticles  oral bioavailability  Schisantherin A  
Small-Sized mPEG PLGA Nanoparticles of Schisantherin A with Sustained Release for Enhanced Brain Uptake and Anti-Parkinsonian Activity Journal article
ACS APPLIED MATERIALS & INTERFACES, 2017,Volume: 9,Issue: 11,Page: 9516-9527
Authors:  Chen, Tongkai;  Li, Chuwen;  Li, Ye;  Yi, Xiang;  Wang, Ruibing;  Lee, Simon Ming-Yuen;  Zheng, Ying
Favorite | View/Download:64/0 | TC[WOS]:21 TC[Scopus]:29 | Submit date:2018/10/30
Brain Delivery  Cellular Uptake  Fluorescence Resonance Energy Transfer (Fret)  Mpeg-plga Nanoparticles  Oral Bioavailability  Schisantherin a  
Oral delivery of a nanocrystal formulation of schisantherin a with improved bioavailability and brain delivery for the treatment of Parkinson's disease Journal article
Molecular Pharmaceutics, 2016,Volume: 13,Issue: 11,Page: 3864-3875
Authors:  Tongkai Chen;  Chuwen Li;  Ye Li;  Xiang Yi;  Simon Ming-Yuen Lee;  Ying Zheng
Favorite | View/Download:11/0 | TC[WOS]:18 TC[Scopus]:23 | Submit date:2018/11/06
Brain Delivery  Dissolution  Nanocrystals  Oral Bioavailability  Parkinson's Disease (Pd)  
Enhanced dissolution, oral bioavailability and brain delivery by formulation schisantherin a into nanocrystals Journal article
Nanomedicine: Nanotechnology, Biology, and Medicine, 2016,Volume: 12,Issue: 2,Page: 503
Authors:  Tongkai Chen;  Ye Li;  Wenjin Wu;  Xiang Yi;  Simon Ming-Yuen Lee;  Ying Zheng
Favorite | View/Download:15/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/04/08
Schisantherin A protects against 6-OHDA-induced dopaminergic neuron damage in zebrafish and cytotoxicity in SH-SY5Y cells through the ROS/NO and AKT/GSK3 β pathways Journal article
JOURNAL OF ETHNOPHARMACOLOGY, 2015,Volume: 170,Page: 8-15
Authors:  Lun Qing Zhang;  Fei Sa;  Cheong Meng Chong;  Ying Wang;  Zhong Yan Zhou;  Raymond Chuen Chung Chang;  Shun Wan Chan;  Pui Man Hoi;  Simon Ming Yuen Lee
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6-hydroxydopamine (6-ohda)  Oxidative Stress  Parkinson׳s Disease  Schisantherin a  
Discovery of novel anti-parkinsonian effect of schisantherin A in in vitro and in vivo Journal article
Neuroscience Letters, 2015,Volume: 593,Page: 7-12
Authors:  Fei Sa;  Lun Qing Zhang;  Cheong Meng Chong;  Bao Jian Guo;  Sai Li;  Zai Jun Zhang;  Ying Zheng;  Pui Man Hoi;  Simon Ming Yuen Lee
Favorite | View/Download:28/0 | TC[WOS]:18 TC[Scopus]:21 | Submit date:2018/11/06
Bcl-2  Dibenzocyclooctadiene Lignans  Neuroprotection  Schisantherin a  
Pharmacokinetic study and optimal formulation of new anti-parkinson natural compound schisantherin A Journal article
Parkinson's Disease, 2015,Volume: 2015
Authors:  Fei Sa;  Bao Jian Guo;  Sai Li;  Zai Jun Zhang;  Hok Man Chan;  Ying Zheng;  Simon Ming Yuen Lee
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Schisantherin A for the treatment of neurodegenerative diseases Patent
专利类型: 发明专利, 专利号: US20150366839A1, 申请日期: 2015-06-17, 公开日期: 2015-12-24
Authors:  Ming Yuen LEE;  Fei SA
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