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Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenuates Abnormal Calvarial Phenotypes in an Apert Syndrome Mouse Model Journal article
Molecular Therapy - Nucleic Acids, 2018,Volume: 13,Page: 291-302
Authors:  Luo F.;  Xie Y.;  Wang Z.;  Huang J.;  Tan Q.;  Sun X.;  Li F.;  Li C.;  Liu M.;  Zhang D.;  Xu M.;  Su N.;  Ni Z.;  Jiang W.;  Chang J.;  Chen H.;  Chen S.;  Xu X.;  Deng C.;  Wang Z.;  Du X.;  Chen L.
Favorite  |  View/Download:13/0  |  Submit date:2018/12/13
Adeno-associated Virus  Apert Syndrome  Craniosynostosis  Fgfr2  Molecular Therapy  Rnai  
The C. elegans intestine as a model for intercellular lumen morphogenesis and in vivo polarized membrane biogenesis at the single-cell level: Labeling by antibody staining, RNAi loss-of-function analysis and imaging Journal article
Journal of Visualized Experiments, 2017,Volume: 2017,Issue: 128
Authors:  Zhang N.;  Khan L.A.;  Membreno E.;  Jafari G.;  Yan S.;  Zhang H.;  Gobel V.
Favorite  |  View/Download:6/0  |  Submit date:2019/01/16
Developmental Biology  Developmental Genetics  Epithelial Polarity  In Situ imagIng  Issue 128  Membrane Biology  Single-cell Analysis  Tubulogenesis  
The C. elegans excretory canal as a model for intracellular lumen morphogenesis and in vivo polarized membrane biogenesis in a single cell: Labeling by GFP-fusions, RNAi interaction screen and imaging Journal article
Journal of Visualized Experiments, 2017,Volume: 2017,Issue: 128
Authors:  Zhang N.;  Membreno E.;  Raj S.;  Zhang H.;  Khan L.A.;  Gobel V.
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Confocal Microscopy  Developmental Biology  Developmental Genetics  Dissecting Fluorescence Microscopy  Intracellular Lumen Morphogenesis  Issue 128  SIngle Cell In Vivo Analysis  Unicellular Tubulogenesis  
The C. elegans Intestine As a Model for Intercellular Lumen Morphogenesis and In Vivo Polarized Membrane Biogenesis at the Single-cell Level: Labeling by Antibody Staining, RNAi Loss-of-function Analysis and Imaging Journal article
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2017,Issue: 128
Authors:  Zhang, Nan;  Khan, Liakot A.;  Membreno, Edward;  Jafari, Gholamali;  Yan, Siyang;  Zhang, Hongjie;  Gobel, Verena
Favorite  |  View/Download:7/0  |  Submit date:2018/10/30
Developmental Biology  Issue 128  Tubulogenesis  epithelial polarity  membrane biology  developmental genetics  single-cell analysis  in situ imaging  
The C. elegans Excretory Canal as a Model for Intracellular Lumen Morphogenesis and In Vivo Polarized Membrane Biogenesis in a Single Cell: labeling by GFP-fusions, RNAi Interaction Screen and Imaging Journal article
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2017,Issue: 128
Authors:  Zhang, Nan;  Membreno, Edward;  Raj, Susan;  Zhang, Hongjie;  Khan, Liakot A.;  Gobel, Verena
Favorite  |  View/Download:6/0  |  Submit date:2018/10/30
Developmental Biology  Issue 128  Unicellular tubulogenesis  intracellular lumen morphogenesis  single cell in vivo analysis  developmental genetics  dissecting fluorescence microscopy  confocal microscopy  
Chronic MeHg exposure modifies the histone H3K4me3 epigenetic landscape in Caenorhabditis elegans Journal article
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 2017,Volume: 191,Page: 109-116
Authors:  Rudgalvyte, Martina;  Peltonen, Juhani;  Lakso, Merja;  Wong, Garry
Favorite  |  View/Download:8/0  |  Submit date:2018/10/30
Chromatin Immunoprecipitation Sequencing (Chip-seq)  Rna Sequencing (Rna-seq)  Heavy Metal  Epigenetics  Mercury  
RNA-Seq Reveals Acute Manganese Exposure Increases Endoplasmic Reticulum Related and Lipocalin mRNAs in Caenorhabditis elegans Journal article
Journal of Biochemical and Molecular Toxicology, 2016,Volume: 30,Issue: 2,Page: 97-105
Authors:  Rudgalvyte M.;  Peltonen J.;  Lakso M.;  Nass R.;  Wong G.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/18
Heavy Metal  Model Organism  Next-generation Sequencing  Rnai  Transcriptomics  
Ammonium tetrathiomolybdate treatment targets the copper transporter ATP7A and enhances sensitivity of breast cancer to cisplatin Journal article
Oncotarget, 2016,Volume: 7,Issue: 51,Page: 84439-84452
Authors:  Chisholm C.L.;  Wang H.;  Wong A.H.-H.;  Vazquez-Ortiz G.;  Chen W.;  Xu X.;  Deng C.-X.
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Atp7a  Breast Cancer  Cisplatin  Copper  Resistance  Sequestering  
An orthologous epigenetic gene expression signature derived from differentiating embryonic stem cells identifies regulators of cardiogenesis Journal article
PLoS ONE, 2015,Volume: 10,Issue: 10
Authors:  Busser B.W.;  Lin Y.;  Yang Y.;  Zhu J.;  Chen G.;  Michelson A.M.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/21
Adapted resistance to the knockdown effect of shRNA-derived Srsf3 siRNAs in mouse littermates Journal article
International Journal of Biological Sciences, 2015,Volume: 11,Issue: 11,Page: 1248-1256
Authors:  Ajiro M.;  Jia R.;  Wang R.-H.;  Deng C.-X.;  Zheng Z.-M.
Favorite  |  View/Download:3/0  |  Submit date:2018/12/13
Shrnas  Srsf3  Transgenic Mouse