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Inactivation of endothelial ADAM17 reduces retinal ischemia-reperfusion induced neuronal and vascular damage Journal article
International Journal of Molecular Sciences, 2020,Volume: 21,Issue: 15,Page: 1-18
Authors:  Gutsaeva,Diana R.;  Shalaby,Lamiaa;  Powell,Folami L.;  Thounaojam,Menaka C.;  Abouhish,Hossameldin;  Wetzstein,Sara A.;  Jadeja,Ravirajsinh N.;  Kwok,Hang Fai;  Martin,Pamela M.;  Bartoli,Manuela
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ADAM17  Neuronal and vascular degeneration  Retinal ischemia-reperfusion  Vascular permeability  
Organoids and Microphysiological Systems: New Tools for Ophthalmic Drug Discovery Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Bai,Jing;  Wang,Chunming
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3D tissue constructs  microphysiological system  ocular  organ-on-a-chip  organoid  
Computer-Aided Formulation Design for a Highly Soluble Lutein-Cyclodextrin Multiple-Component Delivery System Journal article
MOLECULAR PHARMACEUTICS, 2018,Volume: 15,Issue: 4,Page: 1664-1673
Authors:  Zhao, Qianqian;  Miriyala, Nikhila;  Su, Yan;  Chen, Weijie;  Gao, Xuejiao;  Shao, Ling;  Yan, Ru;  Li, Haifeng;  Yao, Xiaojun;  Cao, Dongsheng;  Wang, Yitao;  Ouyang, Defang
View | Adobe PDF | Favorite | View/Download:820/71 | TC[WOS]:16 TC[Scopus]:18 | Submit date:2018/10/30
Lutein  Cyclodextrin  Multiple-component System  Molecular Dynamics Simulation  Bioavailability  Computer-aided Formulation Design  
IGF-1-Mediated Survival from Induced Death of Human Primary Cultured Retinal Pigment Epithelial Cells Is Mediated by an Akt-Dependent Signaling Pathway Journal article
MOLECULAR NEUROBIOLOGY, 2018,Volume: 55,Issue: 3,Page: 1915-1927
Authors:  Zheng, Wenhua;  Meng, Qian;  Wang, Haitao;  Yan, Fengxia;  Little, Peter J.;  Deng, Xinguo;  Lin, Shaofen
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Retinopathy  Serum Deprivation  Cell Signaling  Apoptosis  Growth Factors  
Insulin-like growth factor-1 activates PI3K/Akt signalling to protect human retinal pigment epithelial cells from amiodarone-induced oxidative injury Journal article
BRITISH JOURNAL OF PHARMACOLOGY, 2018,Volume: 175,Issue: 1,Page: 125-139
Authors:  Liao, Rifang;  Yan, Fengxia;  Zeng, Zhuanping;  Wang, Haitao;  Qiu, Kaifeng;  Xu, Jinying;  Zheng, Wenhua
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Zebrafish: A Visual Model to Evaluate the Biofate of Transferrin Receptor-Targeted 7Peptide-Decorated Coumarin 6 Micelles Journal article
ACS Applied Materials and Interfaces, 2017,Volume: 9,Issue: 44,Page: 39048-39058
Authors:  Ye Li;  Xiaoning Song;  Xiang Yi;  Ruibing Wang;  Simon Ming-Yuen Lee;  Xueqing Wang;  Ying Zheng
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7peptide  Biological Barriers  Ligand Density  Poly(Ethylene Glycol)-block-Poly(Ε-caprolactone) Micelles  Transferrin Receptor  Zebrafish  
Multiple growth factors, but not VEGF, stimulate glycosaminoglycan hyperelongation in retinal choroidal endothelial cells Journal article
International Journal of Biological Sciences, 2016,Volume: 12,Issue: 9,Page: 1041-1051
Authors:  Al Gwairi O.;  Osman N.;  Getachew R.;  Zheng W.;  Liang X.-L.;  Kamato D.;  Thach L.;  Little P.J.
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Age related macular degeneration  Bruch's membrane  Growth factors  Proteoglycans  VEGF  Xyloside  
Cellular and Molecular Pathology of Age-Related Macular Degeneration: Potential Role for Proteoglycans Journal article
Journal of Ophthalmology, 2016,Volume: 2016
Authors:  Al Gwairi,Othman;  Thach,Lyna;  Zheng,Wenhua;  Osman,Narin;  Little,Peter J.
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IGF-1 Signaling via the PI3K/Akt Pathway Confers Neuroprotection in Human Retinal Pigment Epithelial Cells Exposed to Sodium Nitroprusside Insult Journal article
Journal of Molecular Neuroscience, 2015,Volume: 55,Issue: 4,Page: 931-940
Authors:  Wang H.;  Liao S.;  Geng R.;  Zheng Y.;  Liao R.;  Yan F.;  Thrimawithana T.;  Little P.J.;  Feng Z.-P.;  Lazarovici P.;  Zheng W.
Favorite | View/Download:7/0 | TC[WOS]:23 TC[Scopus]:24 | Submit date:2018/12/21
Akt  Apoptosis  Insulin-like growth factor-1  MAP kinase  Nitric oxide  Protection  Retinal pigment epithelium  
Nerve growth factor protects retinal ganglion cells against injury induced by retinal ischemia-reperfusion in rats Journal article
Growth Factors, 2015,Volume: 33,Issue: 2,Page: 149-159
Authors:  Chen Q.;  Wang H.;  Liao S.;  Gao Y.;  Liao R.;  Little P.J.;  Xu J.;  Feng Z.-P.;  Zheng Y.;  Zheng W.
Favorite | View/Download:4/0 | TC[WOS]:12 TC[Scopus]:15 | Submit date:2018/12/21
Nerve growth factor  PI-3K/Akt signaling pathway  Retinal ganglion cells  Retinal ischemia-reperfusion