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Signalling pathways regulating galactosaminoglycan synthesis and structure in vascular smooth muscle: Implications for lipoprotein binding and atherosclerosis Journal article
PHARMACOLOGY & THERAPEUTICS, 2018,Volume: 187,Page: 88-97
Authors:  Afroz, Rizwana;  Cao, Yingnan;  Rostam, Muhamad Ashraf;  Ta, Hang;  Xu, Suowen;  Zheng, Wenhua;  Osman, Narin;  Kamato, Danielle;  Little, Peter J.
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Atherosclerosis  Proteoglycans  Galactosaminoglycans  Signalling Pathways  
Flavopiridol inhibits TGF-b-stimulated biglycan synthesis by blocking linker region phosphorylation and nuclear translocation of Smad2 Journal article
Journal of Pharmacology and Experimental Therapeutics, 2018,Volume: 365,Issue: 1,Page: 156-164
Authors:  Rostam M.A.;  Shajimoon A.;  Kamato D.;  Mitra P.;  Piva T.J.;  Getachew R.;  Cao Y.;  Zheng W.;  Osman N.;  Little P.J.
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Flavopiridol Inhibits TGF-beta-Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2 Journal article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2018,Volume: 365,Issue: 1,Page: 156-164
Authors:  Rostam, Muhamad A.;  Shajimoon, Aravindra;  Kamato, Danielle;  Mitra, Partha;  Piva, Terrence J.;  Getachew, Robel;  Cao, Yingnan;  Zheng, Wenhua;  Osman, Narin;  Little, Peter J.
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β-defensin 1 expression in HCV infected liver/liver cancer: An important role in protecting HCV progression and liver cancer development Journal article
Scientific Reports, 2017,Volume: 7,Issue: 1
Authors:  Ling Y.-M.;  Chen J.-Y.;  Guo L.;  Wang C.-Y.;  Tan W.-T.;  Wen Q.;  Zhang S.-D.;  Deng G.-H.;  Lin Y.;  Kwok H.F.
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In situ sequestration of endogenous PDGF-BB with an ECM-mimetic sponge for accelerated wound healing Journal article
BIOMATERIALS, 2017,Volume: 148,Page: 54-68
Authors:  Li, Qiu;  Niu, Yiming;  Diao, Huajia;  Wang, Lintao;  Chen, Xiuping;  Wang, Yitao;  Dong, Lei;  Wang, Chunming
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Biomimetic Scaffolds  Extraceilular Matrix  Polysaccharides  Growth Factors  Wound Healing  
Multiple growth factors, but not VEGF, stimulate glycosaminoglycan hyperelongation in retinal choroidal endothelial cells Journal article
International Journal of Biological Sciences, 2016,Volume: 12,Issue: 9,Page: 1041-1051
Authors:  Al Gwairi O.;  Osman N.;  Getachew R.;  Zheng W.;  Liang X.-L.;  Kamato D.;  Thach L.;  Little P.J.
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Age related macular degeneration  Bruch's membrane  Growth factors  Proteoglycans  VEGF  Xyloside  
The role of specific Smad linker region phosphorylation in TGF-β mediated expression of glycosaminoglycan synthesizing enzymes in vascular smooth muscle Journal article
Cellular Signalling, 2016,Volume: 28,Issue: 8,Page: 956
Authors:  Rostam M.A.;  Kamato D.;  Piva T.J.;  Zheng W.;  Little P.J.;  Osman N.
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Atherosclerosis  Glycosaminoglycan  Signalling  Smad  Transforming growth factor-β  Vascular smooth muscle  
Platelet-derived growth factor-stimulated versican synthesis but not glycosaminoglycan elongation in vascular smooth muscle is mediated via akt phosphorylation Journal article
Cellular Signalling, 2014,Volume: 26,Issue: 5,Page: 912-916
Authors:  Osman N.;  Getachew R.;  Thach L.;  Wang H.;  Su X.;  Zheng W.;  Little P.J.
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Akt  Atherosclerosis  GAG hyperelongation  Platelet-derived growth factor  Proteoglycans  
(S)-[6]-Gingerol inhibits TGF-β-stimulated biglycan synthesis but not glycosaminoglycan hyperelongation in human vascular smooth muscle cells Journal article
Journal of Pharmacy and Pharmacology, 2013,Volume: 65,Issue: 7,Page: 1026-1036
Authors:  Kamato D.;  Babaahmadi Rezaei H.;  Getachew R.;  Thach L.;  Guidone D.;  Osman N.;  Roufogalis B.;  Duke C.C.;  Tran V.H.;  Zheng W.;  Little P.J.
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(S)-[6]-Gingerol  biglycan  proteoglycans  Smad signalling  
Genistein inhibits PDGF-stimulated proteoglycan synthesis in vascular smooth muscle without blocking PDGFβ receptor phosphorylation Journal article
Archives of Biochemistry and Biophysics, 2012,Volume: 525,Issue: 1,Page: 25-31
Authors:  Little P.J.;  Getachew R.;  Rezaei H.B.;  Sanchez-Guerrero E.;  Khachigian L.M.;  Wang H.;  Liao S.;  Zheng W.;  Ballinger M.L.;  Osman N.
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Genistein  Glycosaminoglycans  PDGF receptor phosphorylation  Proteoglycans  Vascular smooth muscle