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Deciphering the Pharmacological Mechanisms of the Huayu-Qiangshen-Tongbi Formula Through Integrating Network Pharmacology and In Vitro Pharmacological Investigation Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Zihao Wang;  Ke-Gang Linghu;  Yuanjia Hu;  Huali Zuo;  Hao Yi;  Shi-Hang Xiong;  Jinjian Lu;  Ging Chan;  Hua Yu;  Run-Yue Huang
Favorite  |  View/Download:16/0  |  Submit date:2019/12/04
Rheumatoid Arthritis  Network Pharmacology  Traditional Chinese Medicine  Huayu-qiangshen-tongbi Formula  In Vitro Validation  
Nuclear localization of Desmoplakin and its involvement in telomere maintenance Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2019,Volume: 15,Issue: 11,Page: 2350-2362
Authors:  Peipei Li;  Yuan Meng;  Yuan Wang;  Jingjing Li;  Manting Lam;  Li Wang;  Li-jun Di
Favorite  |  View/Download:12/0  |  Submit date:2020/05/21
Crispr Bioid Telomere Dsp  
Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines Journal article
CANCERS, 2019,Volume: 11,Issue: 1
Authors:  Yang, GJ;  Ko, CN;  Zhong, HJ;  Leung, CH;  Ma, DL
Favorite  |  View/Download:8/0  |  Submit date:2020/03/24
Cell Cycle Arrest  Kdm5a  Jumonji Domain  Histone Demethylation  Protein-protein Interaction  Virtual Screening  Breast Cancer  Cell Senescence  
Emerging Screening Approaches in the Development of Nrf2-Keap1 Protein-Protein Interaction Inhibitors Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019,Volume: 20,Issue: 18
Authors:  Leung, CH;  Zhang, JT;  Yang, GJ;  Liu, H;  Han, QB;  Ma, DL
Favorite  |  View/Download:5/0  |  Submit date:2020/03/23
Virtual Screening  Keap1-nrf2  Protein-protein Interaction  Inhibitors  Oxidative Stress  
Stereoselective interactions of lactic acid enantiomers with HSA: Spectroscopy and docking application Journal article
FOOD CHEMISTRY, 2019,Volume: 270,Page: 429-435
Authors:  Mu, Hongtao;  Chen, Shaohuan;  Liu, Fengyin;  Xiao, Jianbo;  Huang, Hui;  Zhang, Yuhua;  Sun, Yuanming;  Gao, Xiangyang;  Lei, Hongtao;  Yuan, Xuewen
Favorite  |  View/Download:56/0  |  Submit date:2018/10/30
Lactic Acid Isomers  Human Serum Albumin  Fluorescence Spectroscopy  Circular Dichroism  Docking Simulation  
Cyclin B1 stability is increased by interaction with BRCA1, and its overexpression suppresses the progression of BRCA1-associated mammary tumors Journal article
Experimental and Molecular Medicine, 2018,Volume: 50,Page: 136
Authors:  Choi, Eun Kyung;  Lim, Jeong-A;  Kim, Jong Kwang;  Jang, Moon Sun;  Kim, Sun Eui;  Baek, Hye Jung;  Park, Eun Jung;  Kim, Tae Hyun;  Deng, Chu-Xia;  Wang, Rui-Hong;  Kim, Sang Soo
Favorite  |  View/Download:23/0  |  Submit date:2018/10/30
Internationalization of Traditional/Complementary Medicine products: market entry as medicine Journal article
CHINESE MEDICINE, 2018,Volume: 13
Authors:  Li, Jiatong;  Zhu, Jianfan;  Hu, Hao;  Harnett, Joanna E.;  Lei, Chi Ieong;  Chau, Ka Yin;  Chan, Ging;  Ung, Carolina Oi Lam
View  |  Adobe PDF(933Kb)  |  Favorite  |  View/Download:347/8  |  Submit date:2018/10/30
Traditional Chinese Medicines  Chinese Patent Medicines  Proprietary Chinese Medicines  Traditional And Complementary Medicine  Registration  Internationalization  Quality  Safety  Efficacy  
Structure-guided disruption of the pseudopilus tip complex inhibits the Type II secretion in Pseudomonas aeruginosa Journal article
PLoS Pathogens, 2018,Volume: 14,Issue: 10
Authors:  Zhang Y.;  Faucher F.;  Zhang W.;  Wang S.;  Neville N.;  Poole K.;  Zheng J.;  Jia Z.
Favorite  |  View/Download:10/0  |  Submit date:2019/01/16
Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy Journal article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018,Volume: 57,Issue: 40,Page: 13091-13095
Authors:  Yang, Guan-Jun;  Wang, Wanhe;  Mok, Simon Wing Fai;  Wu, Chun;  Law, Betty Yuen Kwan;  Miao, Xiang-Min;  Wu, Ke-Jia;  Zhong, Hai-Jing;  Wong, Chun-Yuen;  Wong, Vincent Kam Wai;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite  |  View/Download:38/0  |  Submit date:2018/10/30
Drug Discovery  Epigenetics  Medicinal Chemistry  Triple-negative Breast Cancer  
Serum amyloid A promotes LPS clearance and suppresses LPS-induced inflammation and tissue injury Journal article
EMBO REPORTS, 2018,Volume: 19,Issue: 10
Authors:  Cheng, Ni;  Liang, Yurong;  Du, Xiaoping;  Ye, Richard D.
View  |  Adobe PDF(2278Kb)  |  Favorite  |  View/Download:404/16  |  Submit date:2018/10/30
acute-phase response  inflammation  innate immunity  lipopolysaccharide  serum amyloid A