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Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells Journal article
Acta Pharmaceutica Sinica B, 2020,Volume: 10,Issue: 4,Page: 615-627
Authors:  Zhang,Baoyuan;  Lyu,Junfang;  Yang,Eun Ju;  Liu,Yifan;  Wu,Changjie;  Pardeshi,Lakhansing;  Tan,Kaeling;  Chen,Qiang;  Xu,Xiaoling;  Deng,Chu Xia;  Shim,Joong Sup
Favorite | View/Download:75/0 | TC[WOS]:0 TC[Scopus]:3 | Submit date:2020/09/16
BRCA1  Breast cancer  DNA damage  HDAC  Histone deacetylase  Reactive oxygen species  Synthetic lethality  
A Systematic Bioinformatics Workflow With Meta-Analytics Identified Potential Pathogenic Factors of Alzheimer’s Disease Journal article
Frontiers in Neuroscience, 2020,Volume: 14
Authors:  Yuen,Sze Chung;  Zhu,Hongmei;  Leung,Siu Wai
Favorite | View/Download:1/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/11/06
Alzheimer’s disease  bioinformatics  meta-analysis  microarray analysis  RNA sequence analysis  
Deciphering the Pharmacological Mechanisms of the Huayu-Qiangshen-Tongbi Formula Through Integrating Network Pharmacology and In Vitro Pharmacological Investigation Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Zihao Wang;  Ke-Gang Linghu;  Yuanjia Hu;  Huali Zuo;  Hao Yi;  Shi-Hang Xiong;  Jinjian Lu;  Ging Chan;  Hua Yu;  Run-Yue Huang
Favorite | View/Download:27/0 | TC[WOS]:1 TC[Scopus]:4 | Submit date:2019/12/04
Rheumatoid Arthritis  Network Pharmacology  Traditional Chinese Medicine  Huayu-qiangshen-tongbi Formula  In Vitro Validation  
Nuclear localization of Desmoplakin and its involvement in telomere maintenance Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2019,Volume: 15,Issue: 11,Page: 2350-2362
Authors:  Peipei Li;  Yuan Meng;  Yuan Wang;  Jingjing Li;  Manting Lam;  Li Wang;  Li-jun Di
Favorite | View/Download:15/0 | TC[WOS]:1 TC[Scopus]:1 | Submit date:2020/05/21
Crispr Bioid Telomere Dsp  
Stereoselective interactions of lactic acid enantiomers with HSA: Spectroscopy and docking application Journal article
FOOD CHEMISTRY, 2019,Volume: 270,Page: 429-435
Authors:  Mu, Hongtao;  Chen, Shaohuan;  Liu, Fengyin;  Xiao, Jianbo;  Huang, Hui;  Zhang, Yuhua;  Sun, Yuanming;  Gao, Xiangyang;  Lei, Hongtao;  Yuan, Xuewen
Favorite | View/Download:115/0 | TC[WOS]:10 TC[Scopus]:12 | Submit date:2018/10/30
Lactic Acid Isomers  Human Serum Albumin  Fluorescence Spectroscopy  Circular Dichroism  Docking Simulation  
Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines Journal article
CANCERS, 2019,Volume: 11,Issue: 1
Authors:  Yang, GJ;  Ko, CN;  Zhong, HJ;  Leung, CH;  Ma, DL
Favorite | View/Download:13/0 | TC[WOS]:7 TC[Scopus]:7 | Submit date:2020/03/24
Cell Cycle Arrest  Kdm5a  Jumonji Domain  Histone Demethylation  Protein-protein Interaction  Virtual Screening  Breast Cancer  Cell Senescence  
Emerging Screening Approaches in the Development of Nrf2-Keap1 Protein-Protein Interaction Inhibitors Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019,Volume: 20,Issue: 18
Authors:  Leung, CH;  Zhang, JT;  Yang, GJ;  Liu, H;  Han, QB;  Ma, DL
Favorite | View/Download:11/0 | TC[WOS]:3 TC[Scopus]:8 | Submit date:2020/03/23
Virtual Screening  Keap1-nrf2  Protein-protein Interaction  Inhibitors  Oxidative Stress  
Cyclin B1 stability is increased by interaction with BRCA1, and its overexpression suppresses the progression of BRCA1-associated mammary tumors Journal article
Experimental and Molecular Medicine, 2018,Volume: 50,Page: 136
Authors:  Choi, Eun Kyung;  Lim, Jeong-A;  Kim, Jong Kwang;  Jang, Moon Sun;  Kim, Sun Eui;  Baek, Hye Jung;  Park, Eun Jung;  Kim, Tae Hyun;  Deng, Chu-Xia;  Wang, Rui-Hong;  Kim, Sang Soo
Favorite | View/Download:40/0 | TC[WOS]:2 TC[Scopus]:4 | Submit date:2018/10/30
Internationalization of Traditional/Complementary Medicine products: market entry as medicine Journal article
CHINESE MEDICINE, 2018,Volume: 13
Authors:  Li, Jiatong;  Zhu, Jianfan;  Hu, Hao;  Harnett, Joanna E.;  Lei, Chi Ieong;  Chau, Ka Yin;  Chan, Ging;  Ung, Carolina Oi Lam
View | Adobe PDF | Favorite | View/Download:502/10 | TC[WOS]:3 TC[Scopus]:8 | Submit date:2018/10/30
Traditional Chinese Medicines  Chinese Patent Medicines  Proprietary Chinese Medicines  Traditional And Complementary Medicine  Registration  Internationalization  Quality  Safety  Efficacy  
Structure-guided disruption of the pseudopilus tip complex inhibits the Type II secretion in Pseudomonas aeruginosa Journal article
PLoS Pathogens, 2018,Volume: 14,Issue: 10
Authors:  Zhang Y.;  Faucher F.;  Zhang W.;  Wang S.;  Neville N.;  Poole K.;  Zheng J.;  Jia Z.
Favorite | View/Download:16/0 | TC[WOS]:2 TC[Scopus]:6 | Submit date:2019/01/16