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Preparation of orthogonal physicochemical gradients on PDMS surface using microfluidic concentration gradient generator Journal article
Applied Surface Science, 2019,Volume: 471,Page: 213-221
Authors:  Zhou B.;  Gao Y.;  Tian J.;  Tong R.;  Wu J.;  Wen W.
Favorite  |  View/Download:6/0  |  Submit date:2019/04/08
Orthogonal Gradient  Protein Adsorption  Silver Nano-particle  Surface Roughness  
Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library Journal article
Journal of Medicinal Chemistry, 2019,Volume: 62,Issue: 6,Page: 2928-2937
Authors:  Shaikh F.;  Zhao Y.;  Alvarez L.;  Iliopoulou M.;  Lohans C.;  Schofield C.J.;  Padilla-Parra S.;  Siu S.W.I.;  Fry E.E.;  Ren J.;  Stuart D.I.
Favorite  |  View/Download:1/0  |  Submit date:2019/04/04
In vitro immunomodulatory effects of human milk oligosaccharides on murine macrophage RAW264.7 cells Journal article
CARBOHYDRATE POLYMERS, 2019,Volume: 207,Page: 230-238
Authors:  Zhang, Weiyue;  Yan, Jingyu;  Wu, Lehao;  Yu, Yang;  Ye, Richard D.;  Zhang, Yan;  Liang, Xinmiao
Favorite  |  View/Download:3/0  |  Submit date:2019/01/17
Human milk oligosaccharides  Immunomodulator  Nitric oxide  Cytokine  NF-kappa B  MAPKs  
An Integrated Transfer Learning and Multitask Learning Approach for Pharmacokinetic Parameter Prediction Journal article
Molecular Pharmaceutics, 2019,Volume: 16,Issue: 2,Page: 533-541
Authors:  Ye Z.;  Yang Y.;  Li X.;  Cao D.;  Ouyang D.
Favorite  |  View/Download:6/0  |  Submit date:2019/02/14
ADME  deep learning  multitask learning  pharmacokinetic parameters  transfer learning  
Novel neurotoxic peptides from Protopalythoa variabilis virtually interact with voltage-gated sodium channel and display anti-epilepsy and neuroprotective activities in zebrafish Journal article
Archives of Toxicology, 2019,Volume: 93,Issue: 1,Page: 189-206
Authors:  Liao Q.;  Li S.;  Siu S.W.I.;  Morlighem J.-E.R.L.;  Wong C.T.T.;  Wang X.;  Radis-Baptista G.;  Lee S.M.-Y.
Favorite  |  View/Download:0/0  |  Submit date:2019/04/04
Anti-epilepsy  Disulfide bond  Neuroactive peptides  Neuroprotection  Protein docking  Voltage-gated sodium ion channel blocker  
Identification and characterization of antioxidant peptides from hydrolysate of blue-spotted stingray and their stability against thermal, pH and simulated gastrointestinal digestion treatments Conference paper
Authors:  Wong, Fai-Chu;  Xiao, Jianbo;  Ong, Michelle G-Ling;  Pang, Mei-Jing;  Wong, Shao-Jun;  Teh, Lai-Kuan;  Chai, Tsun-Thai
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
Antioxidant peptide  DNA oxidation  Lipid peroxidation  pH stability  Protein oxidation  Purification  Simulated gastrointestinal digestion  Thermal treatment  
Comparative comprehension on the anti-rheumatic Chinese herbal medicine Siegesbeckiae Herba: Combined computational predictions and experimental investigations Journal article
Journal of Ethnopharmacology, 2019,Volume: 228,Page: 200-209
Authors:  Zhang Q.R.;  Zhong Z.F.;  Sang W.;  Xiong W.;  Tao H.X.;  Zhao G.D.;  Li Z.X.;  Ma Q.S.;  Tse A.K.W.;  Hu Y.J.;  Yu H.;  Wang Y.T.
Favorite  |  View/Download:9/0  |  Submit date:2018/12/28
Computational prediction  Difference  Rheumatoid arthritis  Siegesbeckiae Herba  Similarity  
Myricanol mitigates lipid accumulation in 3T3-L1 adipocytes and high fat diet-fed zebrafish via activating AMP-activated protein kinase Conference paper
Authors:  Shen, Shengnan;  Liao, Qiwen;  Feng, Yu;  Liu, Jingxin;  Pan, Ruile;  Lee, Simon Ming-Yuen;  Lin, Ligen
Favorite  |  View/Download:18/0  |  Submit date:2018/10/30
Myricanol  AMP-activated protein kinase  Adipogenesis  Lipid accumulation  Insulin sensitivity  Zebrafish  
Plasma protein binding of dietary polyphenols to human serum albumin: A high performance affinity chromatography approach Conference paper
Authors:  Cao, Hui;  Liu, Xiaojuan;  Ulrih, Natasa Poklar;  Sengupta, Pradeep K.;  Xiao, Jianbo
Favorite  |  View/Download:15/0  |  Submit date:2018/10/30
Flavonoids  Structure-protein binding relationship  Protein binding rate  HSA  
Myricanol mitigates lipid accumulation in 3T3-L1 adipocytes and high fat diet-fed zebrafish via activating AMP-activated protein kinase Journal article
Food Chemistry, 2019,Volume: 270,Page: 305-314
Authors:  Shen S.;  Liao Q.;  Feng Y.;  Liu J.;  Pan R.;  Lee S.M.-Y.;  Lin L.
Favorite  |  View/Download:5/0  |  Submit date:2018/11/06
Adipogenesis  AMP-activated protein kinase  Insulin sensitivity  Lipid accumulation  Myricanol  Zebrafish