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Novel Hsp90 inhibitor platycodin D disrupts Hsp90/Cdc37 complex and enhances the anticancer effect of mTOR inhibitor Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2017,Volume: 330,Page: 65-73
Authors:  Li, Ting;  Chen, Xin;  Dai, Xiao-Yang;  Wei, Bin;  Weng, Qin-Jie;  Chen, Xiuping;  Ouyang, De-Fang;  Yan, Ru;  Huang, Zhang-Jian;  Jiang, Hu-Lin;  Zhu, Hong;  Lu, Jin-Jian
Favorite  |  View/Download:7/0  |  Submit date:2018/10/30
Everolimus  Platycodin d  Hsp90  Cdc37  Egfr  Igf1r  
Platycodin D potentiates proliferation inhibition and apoptosis induction upon AKT inhibition via feedback blockade in non-small cell lung cancer cells Journal article
Scientific Reports, 2016,Volume: 6
Authors:  Li T.;  Chen X.;  Chen X.;  Ma D.L.;  Leung C.H.;  Lu J.J.
Favorite  |  View/Download:6/0  |  Submit date:2018/11/06
Proteomic analysis of hepatocellular carcinoma HepG2 cells treated with platycodin D Journal article
Chinese Journal of Natural Medicines, 2015,Volume: 13,Issue: 9,Page: 673-679
Authors:  Lu J.-J.;  Lu D.-Z.;  Chen Y.-F.;  Dong Y.-T.;  Zhang J.-R.;  Li T.;  Tang Z.-H.;  Yang Z.
Favorite  |  View/Download:3/0  |  Submit date:2018/12/28
2-d Dige  Hepg2  Platycodin d  Proteome  
Platycodin D triggers autophagy through activation of extracellular signal-regulated kinase in hepatocellular carcinoma HepG2 cells Journal article
European Journal of Pharmacology, 2015,Volume: 749,Page: 81
Authors:  Li T.;  Tang Z.-H.;  Xu W.-S.;  Wu G.-S.;  Wang Y.-F.;  Chang L.-L.;  Zhu H.;  Chen X.-P.;  Wang Y.-T.;  Chen Y.;  Lu J.-J.
Favorite  |  View/Download:2/0  |  Submit date:2018/10/31
Autophagy  Chloroquine  Erk  Hepg2  Platycodin d  Protective  
Platycodin D induces apoptosis and triggers ERK- and JNK-mediated autophagy in human hepatocellular carcinoma BEL-7402 cells Journal article
Acta Pharmacologica Sinica, 2015,Volume: 36,Issue: 12,Page: 1503
Authors:  Li T.;  Xu X.-H.;  Tang Z.-H.;  Wang Y.-F.;  Leung C.-H.;  Ma D.-L.;  Chen X.-P.;  Wang Y.-T.;  Chen Y.;  Lu J.-J.
Favorite  |  View/Download:4/0  |  Submit date:2018/10/31
Apoptosis  Autophagy  Erk  Baf  Bel-7402 Cells  Chloroquine  Human Hepatocellular Carcinoma  Jnk  Platycodin d  Sp600125  U0126  
Platycodin D from Platycodonis Radix enhances the anti-proliferative effects of doxorubicin on breast cancer MCF-7 and MDA-MB-231 cells Journal article
Chinese Medicine (United Kingdom), 2014,Volume: 9,Issue: 1
Authors:  Tang Z.-H.;  Li T.;  Gao H.-W.;  Sun W.;  Chen X.-P.;  Wang Y.-T.;  Lu J.-J.
Favorite  |  View/Download:2/0  |  Submit date:2018/10/31
Platycodin D induces apoptosis, and inhibits adhesion, migration and invasion in HepG2 hepatocellular carcinoma cells Journal article
Asian Pacific Journal of Cancer Prevention, 2014,Volume: 15,Issue: 4,Page: 1745
Authors:  Li T.;  Xu W.-S.;  Wu G.-S.;  Chen X.-P.;  Wang Y.-T.;  Lu J.-J.
Favorite  |  View/Download:7/0  |  Submit date:2018/10/30
Apoptosis  Cancer  Hepg2  Metastasis  Platycodin d  
A sensitive method for determination of platycodin D in rat plasma using liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study Journal article
Planta Medica, 2012,Volume: 78,Issue: 3,Page: 244-251
Authors:  Pei L.;  Bao Y.;  Ma L.;  Wang Q.;  Ye Y.;  Han X.;  Liu S.;  Chen X.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/28
Campanulaceae  Lc/ms/ms  Pharmacokinetics  Platycodin d  PlA.ycodon GrA.diflorum A. Dc  Tubeimoside i