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Modeling analysis of potential target of dolastatin 16 by computational virtual screening Journal article
Chemical and Pharmaceutical Bulletin, 2018,Volume: 66,Issue: 6,Page: 602-607
Authors:  Liang T.-T.;  Zhao Q.;  He S.;  Mu F.-Z.;  Deng W.;  Han B.-N.
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Dolastatin 16  Fkbp1a  Molecular Docking  Pharmmapper  
Discovery and preliminary SAR of 14-aryloxy-andrographolide derivatives as antibacterial agents with immunosuppressant activity Journal article
RSC ADVANCES, 2018,Volume: 8,Issue: 17,Page: 9440-9456
Authors:  Li, Feng;  Li, Xiao-Min;  Sheng, Dekuan;  Chen, Shao-Ru;  Nie, Xin;  Liu, Zhuyun;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Wang, Ying;  Zhou, Guo-Chun
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Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View  |  Adobe PDF(2766Kb)  |  Favorite  |  View/Download:362/9  |  Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
4-Aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-ones as N-formyl peptide receptor 1 (FPR1) antagonists Journal article
BIOCHEMICAL PHARMACOLOGY, 2017,Volume: 142,Page: 120-132
Authors:  Kirpotina, Liliya N.;  Schepetkin, Igor A.;  Khlebnikov, Andrei I.;  Ruban, Olga I.;  Ge, Yunjun;  Ye, Richard D.;  Kominsky, Douglas J.;  Quinn, Mark T.
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Antagonist Formyl peptide receptor  1H-pyrrol-2(5H)-one  Neutrophil  Molecular modeling  
Discovery of Novel ROCK1 Inhibitors via Integrated Virtual Screening Strategy and Bioassays Journal article
Scientific Reports, 2015,Volume: 5
Authors:  Mingyun Shen;  Sheng Tian;  Peichen Pan;  Huiyong Sun;  Dan Li;  Youyong Li;  Hefeng Zhou;  Chuwen Li;  Simon Ming-Yuen Lee;  Tingjun Hou
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Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening Journal article
Methods, 2015,Volume: 71,Issue: C,Page: 38-43
Authors:  Leung K.-H.;  Liu L.-J.;  Lin S.;  Lu L.;  Zhong H.-J.;  Susanti D.;  Rao W.;  Wang M.;  Che W.I.;  Chan D.S.H.;  Leung C.-H.;  Chan P.W.H.;  Ma D.-L.
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Pharmacophore  Protein-protein interaction  STAT3  Virtual screening  
Pharmacophore modeling for the identification of small-molecule inhibitors of TACE Journal article
Methods, 2015,Volume: 71,Issue: C,Page: 92-97
Authors:  Liu L.-J.;  Leung K.-H.;  Lin S.;  Chan D.S.-H.;  Susanti D.;  Rao W.;  Chan P.W.H.;  Ma D.-L.;  Leung C.-H.
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Inhibitor  Pharmacophore  TACE  Tumor necrosis factor  Virtual screening  
Discovery of deoxyvasicinone derivatives as inhibitors of NEDD8-activating enzyme Journal article
Methods, 2015,Volume: 71,Issue: C,Page: 71-76
Authors:  Zhong H.-J.;  Leung K.-H.;  Lin S.;  Chan D.S.-H.;  Han Q.-B.;  Chan S.L.-F.;  Ma D.-L.;  Leung C.-H.
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Deoxyvasicinone  Drug discovery  NEDD8  Pharmacophore  Ubiquitin-like  
Recent advances in structure-based drug design and virtual screening of VEGFR tyrosine kinase inhibitors Journal article
Methods, 2015,Volume: 71,Issue: C,Page: 85-91
Authors:  Pui Man Hoi;  Shang Li;  Chi Teng Vong;  Hisa Hui Ling Tseng;  Yiu Wa Kwan;  Simon Ming-Yuen Lee
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Molecular Docking  Pharmacophore Modeling  Vegfr2  Vegfr2 Inhibitors  Virtual Screening  
SAR studies of 3,14,19-derivatives of andrographolide on anti-proliferative activity to cancer cells and toxicity to zebrafish: An in vitro and in vivo study Journal article
RSC Advances, 2015,Volume: 5,Issue: 29,Page: 22510-22526
Authors:  Yuran Peng;  Jingjing Li;  Yicheng Sun;  Judy Yuet-Wa Chan;  Dekuan Sheng;  Kun Wang;  Ping Wei;  Pingkai Ouyang;  Decai Wang;  Simon Ming Yuen Lee;  Guo-Chun Zhou
Favorite  |  View/Download:15/0  |  Submit date:2018/11/06