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Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View  |  Adobe PDF(2766Kb)  |  Favorite  |  View/Download:119/4  |  Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Mori Cortex regulates P-glycoprotein in Caco-2 cells and colons from rats with experimental colitis via direct and gut microbiota-mediated mechanisms Journal article
RSC ADVANCES, 2017,Volume: 7,Issue: 5,Page: 2594-2605
Authors:  Jing, Wanghui;  Gao, Xuejiao;  Han, Beilei;  Wei, Bin;  Hu, Nan;  Li, Sai;  Yan, Ru;  Wang, Yitao
View  |  Adobe PDF(1193Kb)  |  Favorite  |  View/Download:129/7  |  Submit date:2018/10/30
An effective analytic method for detecting tissue-specific genes in RNA-seq experiments Journal article
Pharmacogenomics, 2015,Volume: 16,Issue: 16,Page: 1769-1779
Authors:  Zhao G.;  Li Q.;  Wang I.-M.;  Liu X.;  Fang X.;  Zhang X.D.
Favorite  |  View/Download:1/0  |  Submit date:2019/01/03
consecutive procedures  generalization of Tukey's test  next-generation sequencing  RNA-Seq  tissue-specific gene  
Precision Medicine, Personalized Medicine, Omics and Big Data: Concepts and Relationships Journal article
Journal of Pharmacogenomics and Pharmacoproteomics, 2015
Authors:  Xiaohua Douglas Zhang
Favorite  |  View/Download:2/0  |  Submit date:2019/01/11
V101L of human formyl peptide receptor 1 (FPR1) increases receptor affinity and augments the antagonism mediated by cyclosporins Journal article
Biochemical Journal, 2013,Volume: 451,Issue: 2,Page: 245-255
Authors:  Zhou C.;  Zhou Y.;  Wang J.;  Feng Y.;  Wang H.;  Xue J.;  Chen Y.;  Ye R.D.;  Wang M.-W.
Favorite  |  View/Download:2/0  |  Submit date:2018/11/07
Cyclosporin  Formyl peptide receptor 1 (FPR1)  Haplotype  Pharmacogenomics  Receptor affinity  Single nucleotide polymorphism  
Assessing the size of gene or RNAi effects in multifactor high-throughput experiments Journal article
Pharmacogenomics, 2010,Volume: 11,Issue: 2,Page: 199-213
Authors:  Zhang X.D.
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C+-probability  Contrast core  Contrast variable  Dual-flashlight plot  High-throughput  Multifactor analysis of variance  Standardized mean of contrast  
A method for effectively comparing gene effects in multiple conditions in RNAi and expression-profiling research Journal article
Pharmacogenomics, 2009,Volume: 10,Issue: 3,Page: 345-358
Authors:  Zhang X.D.
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c+-probability  Comparing gene effects  Contrast variable  Expression profiling  High-throughput  RNAi  Standardized mean of contrast  Statistical analysis  
Robust statistical methods for hit selection RNA interference high-throughput screening experiments Journal article
Pharmacogenomics, 2006,Volume: 7,Issue: 3,Page: 299-309
Authors:  Zhang X.D.;  Yang X.C.;  Chung N.;  Gates A.;  Stec E.;  Kunapuli P.;  Holder D.J.;  Ferner M.;  Espeseth A.S.
Favorite  |  View/Download:8/0  |  Submit date:2019/01/03
Experimentwise  High-throughput screening  Hit selection  Median  Median absolute deviation  Plate-well series plot  Platewise  Quartile-based method  RNA interference  Statistical methods