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NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite | View/Download:76/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/09/16
Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Sun,Xianding;  Zhou,Yang;  Zhang,Ruobin;  Wang,Zuqiang;  Xu,Meng;  Zhang,Dali;  Huang,Junlan;  Luo,Fengtao;  Li,Fangfang;  Ni,Zhenhong;  Zhou,Siru;  Chen,Hangang;  Chen,Shuai;  Chen,Liang;  Du,Xiaolan;  Chen,Bo;  Huang,Haiyang;  Liu,Peng;  Yin,Liangjun;  Qiu,Juhui;  Chen,Di;  Deng,Chuxia;  Xie,Yangli;  Luo,Lingfei;  Chen,Lin
Favorite | View/Download:75/0 | TC[WOS]:1 TC[Scopus]:2 | Submit date:2020/09/16
FGFR3 deficiency enhances CXCL12-dependent chemotaxis of macrophages via upregulating CXCR7 and aggravates joint destruction in mice Journal article
Annals of the Rheumatic Diseases, 2020,Volume: 79,Issue: 1,Page: 112-122
Authors:  Kuang,Liang;  Wu,Jiangyi;  Su,Nan;  Qi,Huabing;  Chen,Hangang;  Zhou,Siru;  Xiong,Yan;  Du,Xiaolan;  Tan,Qiaoyan;  Yang,Jing;  Jin,Min;  Luo,Fengtao;  Ouyang,Junjie;  Zhang,Bin;  Wang,Zuqiang;  Jiang,Wanling;  Chen,Liang;  Chen,Shuai;  Wang,Ziming;  Liu,Peng;  Yin,Liangjun;  Guo,Fengjin;  Deng,Chuxia;  Chen,Di;  Liu,Chuanju;  Xie,Yangli;  Ni,Zhenhong;  Chen,Lin
Favorite | View/Download:74/0 | TC[WOS]:3 TC[Scopus]:4 | Submit date:2020/09/16
arthritis  chemokines  inflammation  synovitis  
Stagewise keratinocyte differentiation from human embryonic stem cells by defined signal transduction modulators Journal article
International Journal of Biological Sciences, 2020,Volume: 16,Issue: 8,Page: 1450-1462
Authors:  Zhong,Hui;  Ren,Zhili;  Wang,Xiaoyan;  Miao,Kai;  Ni,Wenjun;  Meng,Ya;  Lu,Ligong;  Wang,Chunming;  Liu,Weiwei;  Deng,Chu Xia;  Xu,Ren He;  Chen,Guokai
Favorite | View/Download:72/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/09/16
Defined factors  Human embryonic stem cells  Keratinocyte differentiation  
The metabolic footprint during adipocyte commitment highlights ceramide modulation as an adequate approach for obesity treatment Journal article
EBioMedicine, 2020,Volume: 51
Authors:  Hou,Weilong;  Chen,Qiang;  Wang,Haitao;  Qiu,Pengxiang;  Lyu,Xueying;  Chen,Weiping;  Chua,Melvin L.K.;  Chinn,Y. Eugene;  Deng,Chu Xia;  Wang,Ruihong
Favorite | View/Download:73/0 | TC[WOS]:0 TC[Scopus]:1 | Submit date:2020/09/16
Adipogenesis  Apoptosis  Ceramide  Epigenetic modification  Metabolic landscape  Metabolomics  Obesity  
Identifying the core bacterial microbiome of hydrocarbon degradation and a shift of dominant methanogenesis pathways in the oil and aqueous phases of petroleum reservoirs of different temperatures from China Journal article
BIOGEOSCIENCES, 2019,Volume: 16,Issue: 1,Page: 4229-4241
Authors:  Zhou, Zhichao;  Liang, Bo;  Wang, Li-Ying;  Liu, Jin-Feng;  Mu, Bo-Zhong;  Shim, Hojae;  Gu, Ji-Dong
Favorite | View/Download:11/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/05/29
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 10,Page: 1279-1291
Authors:  Lei Fan;  Xiao-xia Qiu;  Zhi-yuan Zhu;  Jian-lu Lv;  Jian Lu;  Fei Mao;  Jin Zhu;  Jia-ying Wang;  Xiao-wei Guan;  Jing Chen;  Jin Ren;  Ji-ming Ye;  Yong-hua Zhao;  Jian Li;  Xu Shen
Favorite | View/Download:16/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2020/04/14
App/ps1 Transgenic Mice  Alzheimer’s Disease  Autophagy  Inflammation  Nitazoxanide  
Deciphering the Pharmacological Mechanisms of the Huayu-Qiangshen-Tongbi Formula Through Integrating Network Pharmacology and In Vitro Pharmacological Investigation Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Zihao Wang;  Ke-Gang Linghu;  Yuanjia Hu;  Huali Zuo;  Hao Yi;  Shi-Hang Xiong;  Jinjian Lu;  Ging Chan;  Hua Yu;  Run-Yue Huang
Favorite | View/Download:22/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2019/12/04
Rheumatoid Arthritis  Network Pharmacology  Traditional Chinese Medicine  Huayu-qiangshen-tongbi Formula  In Vitro Validation  
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 9,Page: 1193-1204
Authors:  Ting-ting Zhou;  Tong Zhao;  Fei Ma;  Yi-nan Zhang;  Jing Jiang;  Yuan Ruan;  Qiu-ying Yan;  Gai-hong Wang;  Jin Ren;  Xiao-wei Guan;  Jun Guo;  Yong-hua Zhao;  Ji-ming Ye;  Li-hong Hu;  Jing Chen;  Xu Shen
Favorite | View/Download:9/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2020/04/14
Type 2 Diabetes Mellitus  Hepatic Gluconeogenesis  Ampk Signaling Pathway  (e)-3-(2-(Quinoline-4-yl)Vinyl)-1h-indol-6-ol (Qvo)  4-[2-(1h-indol-3-yl)Vinyl]Quinoline (Ivq)  Prodrug  
CeRNA network analysis and functional enrichment of salt sensitivity of blood pressure by weighted-gene co-expression analysis Journal article
PEERJ, 2019
Authors:  Han Cao;  Han Qi;  Zheng Liu;  Wen-Juan Peng;  Chun-Yue Guo;  Yan-Yan Sun;  Christine Pao;  Yu-Tao Xiang;  Ling Zhang
Favorite | View/Download:13/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2020/05/26
Competitive Endogenous Rnas  Gene Set Enrichment Analysis  Long Non-coding Rnas  Salt Sensitivity Of Blood Pressure  Weighted Gene Co-expression Network Analysis