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A Cucurbit[8]uril2:2 Complex with a Negative pKa Shift Journal article
CHEMISTRY-A EUROPEAN JOURNAL, 2019,Volume: 25,Issue: 54,Page: 12552-12559
Authors:  Hang Yin;  Qian Cheng;  Roselyne Rosas;  StØphane Viel;  ValØrie Monnier;  Laurence Charles;  Didier Siri;  Didier Gigmes;  Olivier Ouari;  Ruibing Wang;  Anthony Kermagoret;  David Bardelang
Favorite | View/Download:19/0 | TC[WOS]:4 TC[Scopus]:4 | Submit date:2020/04/03
2:2complexes  Cucurbituril  Host–guestsystems  Imidazoles  Viologen  
Neuroprotective Effects of BHDPC, a Novel Neuroprotectant, on Experimental Stroke by Modulating Microglia Polarization Journal article
ACS CHEMICAL NEUROSCIENCE, 2019,Volume: 10,Issue: 5,Page: 2434-2449
Authors:  Chuwen Li;  Yaqi Bian;  Yu Feng;  Fan Tang;  Liang Wang;  Maggie Pui Man Hoi;  Dan Ma;  Chao Zhao;  Simon Ming Yuen Lee
Favorite | View/Download:228/0 | TC[WOS]:4 TC[Scopus]:9 | Submit date:2020/01/16
Bhdpc  Ischemic Stroke  Microglia  Nf-κb  Creb  Pka  
Canthin-6-One Accelerates Alpha-Synuclein Degradation by Enhancing UPS Activity: Drug Target Identification by CRISPR-Cas9 Whole Genome-Wide Screening Technology Journal article
FRONTIERS IN PHARMACOLOGY, 2019
Authors:  Ning-Ning Yuan;  Cui-Zan Cai;  Ming-Yue Wu;  Qi Zhu;  HuanXing Su;  Min Li;  JiaoYan Ren;  Jie-Qiong Tan;  Jia-Hong Lu
Favorite | View/Download:29/0 | TC[WOS]:3 TC[Scopus]:5 | Submit date:2020/04/14
Canthin-6-one  Parkinson’s Disease  Alpha-synuclein  Ubiquitin-proteasome-system  Crispr/cas9  Rpn2/psmd1  Pka  
BHDPC Is a Novel Neuroprotectant That Provides Anti-neuroinflammatory and Neuroprotective Effects by Inactivating NF-kappa B and Activating PKA/CREB Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Li, Chuwen;  Chen, Tongkai;  Zhou, Hefeng;  Feng, Yu;  Hoi, Maggie P. M.;  Ma, Dan;  Zhao, Chao;  Zheng, Ying;  Lee, Simon M. Y.
Favorite | View/Download:42/0 | TC[WOS]:4 TC[Scopus]:5 | Submit date:2018/10/30
Bhdpc  Neuroinflammation  Microglia  Nf-kappa b  Creb  Pka  
BHDPC is a novel neuroprotectant that provides anti-neuroinflammatory and neuroprotective effects by inactivating NF-κB and activating PKA/CREB Journal article
Frontiers in Pharmacology, 2018,Volume: 9,Issue: JUN
Authors:  Li C.;  Chen T.;  Zhou H.;  Feng Y.;  Hoi M.P.M.;  Ma D.;  Zhao C.;  Zheng Y.;  Lee S.M.Y.
Favorite | View/Download:13/0 | TC[WOS]:4 TC[Scopus]:5 | Submit date:2018/11/06
BHDPC  CREB  Microglia  Neuroinflammation  NF-κB  PKA  
Novel phosphodiesterase 4 inhibitor FCPR03 alleviates lipopolysaccharide-induced neuroinflammation by regulation of the cAMP/PKA/CREB signaling pathway and NF-κB inhibition Journal article
Journal of Pharmacology and Experimental Therapeutics, 2017,Volume: 362,Issue: 1,Page: 67-77
Authors:  Zou Z.-Q.;  Chen J.-J.;  Feng H.-F.;  Cheng Y.-F.;  Wang H.-T.;  Zhou Z.-Z.;  Guo H.-B.;  Zheng W.;  Xu J.-P.
Favorite | View/Download:8/0 | TC[WOS]:12 TC[Scopus]:16 | Submit date:2018/12/21
Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-kappa B Inhibition Journal article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2017,Volume: 362,Issue: 1,Page: 67-77
Authors:  Zou, Zheng-Qiang;  Chen, Jia-Jia;  Feng, Hong-Fang;  Cheng, Yu-Fang;  Wang, Hai-Tao;  Zhou, Zhong-Zhen;  Guo, Hai-Biao;  Zheng, Wenhua;  Xu, Jiang-Ping
Favorite | View/Download:25/0 | TC[WOS]:12 TC[Scopus]:16 | Submit date:2018/10/30
Encapsulation of Vitamin B1 and its phosphate derivatives by cucurbit[7]uril: Tunability of the binding site and affinity by the presence of phosphate groups Journal article
Journal of Organic Chemistry, 2016,Volume: 81,Issue: 3,Page: 1300
Authors:  Li S.;  Yin H.;  Wyman I.W.;  Zhang Q.;  Macartney D.H.;  Wang R.
Favorite | View/Download:14/0 | TC[WOS]:31 TC[Scopus]:33 | Submit date:2018/10/30
Inhibition of C(2)-H Activity on Alkylated Imidazolium Monocations and Dications upon Inclusion by Cucurbit[7]uril Journal article
Journal of Organic Chemistry, 2016,Volume: 81,Issue: 19,Page: 9494
Authors:  Li S.;  Wyman I.W.;  Wang C.;  Wang Y.;  Macartney D.H.;  Wang R.
Favorite | View/Download:9/0 | TC[WOS]:12 TC[Scopus]:12 | Submit date:2018/10/31
Discovery of a novel neuroprotectant, BHDPC, that protects against MPP+/MPTP-induced neuronal death in multiple experimental models Journal article
Free Radical Biology and Medicine, 2015,Volume: 89,Page: 1057-1066
Authors:  Cheong-Meng Chong;  Dan Ma;  Chao Zhao;  Robin J.M. Franklin;  Zhong-Yan Zhou;  Nana Ai;  Chuwen Li;  Huidong Yu;  Tingjun Hou;  Tingjun Hou;  Simon Ming-Yuen Lee
Favorite | View/Download:20/0 | TC[WOS]:11 TC[Scopus]:14 | Submit date:2018/11/06
Mpp++++  Neurodegeneration  Rat Organotypiccerebellarcultures  Zebrafish