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BHDPC is a novel neuroprotectant that provides anti-neuroinflammatory and neuroprotective effects by inactivating NF-κB and activating PKA/CREB Journal article
Frontiers in Pharmacology, 2018,Volume: 9,Issue: JUN
Authors:  Li C.;  Chen T.;  Zhou H.;  Feng Y.;  Hoi M.P.M.;  Ma D.;  Zhao C.;  Zheng Y.;  Lee S.M.Y.
Favorite  |  View/Download:4/0  |  Submit date:2018/11/06
BHDPC  CREB  Microglia  Neuroinflammation  NF-κB  PKA  
BHDPC Is a Novel Neuroprotectant That Provides Anti-neuroinflammatory and Neuroprotective Effects by Inactivating NF-kappa B and Activating PKA/CREB Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Li, Chuwen;  Chen, Tongkai;  Zhou, Hefeng;  Feng, Yu;  Hoi, Maggie P. M.;  Ma, Dan;  Zhao, Chao;  Zheng, Ying;  Lee, Simon M. Y.
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BHDPC  neuroinflammation  microglia  NF-kappa B  CREB  PKA  
Novel phosphodiesterase 4 inhibitor FCPR03 alleviates lipopolysaccharide-induced neuroinflammation by regulation of the cAMP/PKA/CREB signaling pathway and NF-κB inhibition Journal article
Journal of Pharmacology and Experimental Therapeutics, 2017,Volume: 362,Issue: 1,Page: 67-77
Authors:  Zou Z.-Q.;  Chen J.-J.;  Feng H.-F.;  Cheng Y.-F.;  Wang H.-T.;  Zhou Z.-Z.;  Guo H.-B.;  Zheng W.;  Xu J.-P.
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Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF-kappa B Inhibition Journal article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2017,Volume: 362,Issue: 1,Page: 67-77
Authors:  Zou, Zheng-Qiang;  Chen, Jia-Jia;  Feng, Hong-Fang;  Cheng, Yu-Fang;  Wang, Hai-Tao;  Zhou, Zhong-Zhen;  Guo, Hai-Biao;  Zheng, Wenhua;  Xu, Jiang-Ping
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Encapsulation of Vitamin B1 and its phosphate derivatives by cucurbit[7]uril: Tunability of the binding site and affinity by the presence of phosphate groups Journal article
Journal of Organic Chemistry, 2016,Volume: 81,Issue: 3,Page: 1300
Authors:  Li S.;  Yin H.;  Wyman I.W.;  Zhang Q.;  Macartney D.H.;  Wang R.
Favorite  |  View/Download:6/0  |  Submit date:2018/10/30
Inhibition of C(2)-H Activity on Alkylated Imidazolium Monocations and Dications upon Inclusion by Cucurbit[7]uril Journal article
Journal of Organic Chemistry, 2016,Volume: 81,Issue: 19,Page: 9494
Authors:  Li S.;  Wyman I.W.;  Wang C.;  Wang Y.;  Macartney D.H.;  Wang R.
Favorite  |  View/Download:3/0  |  Submit date:2018/10/31
Discovery of a novel neuroprotectant, BHDPC, that protects against MPP+/MPTP-induced neuronal death in multiple experimental models Journal article
Free Radical Biology and Medicine, 2015,Volume: 89,Page: 1057-1066
Authors:  Chong C.-M.;  Ma D.;  Zhao C.;  Franklin R.J.M.;  Zhou Z.-Y.;  Ai N.;  Li C.;  Yu H.;  Hou T.;  Sa F.;  Ming-Yuen Lee S.
Favorite  |  View/Download:6/0  |  Submit date:2018/11/06
Mpp++  Neurodegeneration  Rat Organotypiccerebellarcultures  Zebrafish  
Spectrophotometric pKa determination of ionizable pharmaceuticals: Resolution of molecules with weak pH-dependent spectral shift Journal article
Journal of Pharmaceutical and Biomedical Analysis, 2015,Volume: 114,Page: 88-96
Authors:  Dohoda D.;  Tsinman K.;  Tsinman O.;  Wang H.;  Tam K.Y.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/18
Alternating Least Square Analysis  Ionization  Physiochemical Property  Pka  Uv Absorption Spectroscopy  
Differential regulation of kit ligand A (kitlga) expression in the zebrafish ovarian follicle cells - Evidence for the existence of a cyclic adenosine 3 ', 5 ' monophosphate-mediated binary regulatory system during folliculogenesis Journal article
MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2015,Volume: 402,Issue: C,Page: 21-31
Authors:  Yao, Kai;  Ge, Wei
Favorite  |  View/Download:5/0  |  Submit date:2018/12/10
Kit Ligand a  Camp  Pka  Epac  Ovary  Zebrafish  
The chemerin receptor CMKLR1 is a functional receptor for amyloid-β peptide Journal article
Journal of Alzheimer's Disease, 2014,Volume: 43,Issue: 1,Page: 227-242
Authors:  Peng L.;  Yu Y.;  Liu J.;  Li S.;  He H.;  Cheng N.;  Ye R.D.
Favorite  |  View/Download:2/0  |  Submit date:2018/11/07
Alzheimer's disease  amyloid-β  chemerin receptor  chemotaxis  microglial cells