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Rapid identification of antimicrometastases drugs using integrated model systems with two dimensional monolayer, three dimensional spheroids, and zebrafish xenotransplantation tumors Journal article
BIOTECHNOLOGY AND BIOENGINEERING, 2018,Volume: 115,Issue: 11,Page: 2828-2843
Authors:  Fu, Afu;  Peh, Yu Ming;  Ngan, Weida;  Wei, Na;  Luo, Kathy Qian
Favorite  |  View/Download:1/0  |  Submit date:2019/01/17
antimetastasis drug discovery  fluorescence resonance energy transfer  PI3K  AKT pathway  three dimensional tumor spheroids  zebrafish xenograft tumor model  
Toosendanin, a natural product, inhibited TGF-1-induced epithelial-mesenchymal transition through ERK/Snail pathway Journal article
PHYTOTHERAPY RESEARCH, 2018,Volume: 32,Issue: 10,Page: 2009-2020
Authors:  Luo, Weiwei;  Liu, Xin;  Sun, Wen;  Lu, Jin-Jian;  Wang, Yitao;  Chen, Xiuping
View  |  Adobe PDF(2621Kb)  |  Favorite  |  View/Download:245/23  |  Submit date:2018/10/30
Emt  Erk1/2  Snail  Lung Cancer  Toosendanin  
Tanshinone IIA attenuates insulin like growth factor 1-induced cell proliferation in PC12 cells through the PI3K/Akt and MEK/ERK pathways Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 9
Authors:  Wang H.;  Su X.;  Fang J.;  Xin X.;  Zhao X.;  Gaur U.;  Wen Q.;  Xu J.;  Little P.J.;  Zheng W.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/21
Akt  Antiproliferation  ERK  IGF-1R  Tanshinone IIA  
In vitro and clinical data analysis of Osteopontin as a prognostic indicator in colorectal cancer Journal article
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2018,Volume: 22,Issue: 9,Page: 4097-4105
Authors:  Wei, Ran;  Wong, Janet Pik Ching;  Lyu, Peng;  Xi, Xinping;  Tong, Olivia;  Zhang, Shu-Dong;  Yuen, Hiu Fung;  Shirasawa, Senji;  Kwok, Hang Fai
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Colorectal Cancer  Connectivity Mapping  Osteopontin  Survival  
Hepatorenal protective effects of medicinal herbs in An-Gong-Niu-Huang Wan (AGNH) against cinnabar- and realgar-induced oxidative stress and inflammatory damage in mice Conference paper
FOOD AND CHEMICAL TOXICOLOGY, Kunming, PEOPLES R CHINA, AUG 25-30, 2018
Authors:  Li, Ao;  Zhang, Jing-Yao;  Xiao, Xiao;  Wang, Song-Song;  Wan, Jian-Bo;  Chai, Yu-Shuang;  Li, Peng;  Wang, Yi-Tao
Favorite  |  View/Download:35/0  |  Submit date:2018/10/30
An-gong-niu-huang Wan  Cinnabar  Realgar  Oxidative Stress  Inflammation  Detoxification  
Pinostrobin Exerts Neuroprotective Actions in Neurotoxin-Induced Parkinson's Disease Models through Nrf2 Induction Journal article
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018,Volume: 66,Issue: 31,Page: 8307-8318
Authors:  Li, Chuwen;  Tang, Benqin;  Feng, Yu;  Tang, Fan;  Hoi, Maggie Pui-Man;  Su, Ziren;  Lee, Simon Ming-Yuen
Favorite  |  View/Download:8/0  |  Submit date:2018/10/31
Pinostrobin  Parkinson's Disease  Neurotoxin  Nrf2  
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:  Cui, Guozhen;  Xin, Qiqi;  Tseng, Hisa Hui Ling;  Hoi, Maggie PuiMan;  Wang, Yan;  Yang, Binrui;  Choi, InLeng;  Wang, Yuqiang;  Yuan, Rong;  Chen, Keji;  Cong, Weihong;  Lee, Simon MingYuen
View  |  Adobe PDF(3018Kb)  |  Favorite  |  View/Download:104/3  |  Submit date:2018/10/30
Cardioprotection  Angiogenesis  ADTM  Zebrafish  VEGF  
Interference of Quercetin on Astragalus Polysaccharide-Induced Macrophage Activation Journal article
MOLECULES, 2018,Volume: 23,Issue: 7
Authors:  Li, Zhi-Peng;  Liu, Hong-Bing;  Zhang, Quan-Wei;  Li, Li-Feng;  Bao, Wan-Rong;  Ma, Dik-Lung;  Leung, Chung-Hang;  Bian, Zhao-Xiang;  Lu, Ai-Ping;  Han, Quan-Bin
View  |  Adobe PDF(1815Kb)  |  Favorite  |  View/Download:111/4  |  Submit date:2018/10/30
astragalus polysaccharide  quercetin  cytokines  macrophage  foods  
Schisantherin a attenuates neuroinflammation in activated microglia: Role of Nrf2 activation through ERK phosphorylation Journal article
Cellular Physiology and Biochemistry, 2018,Volume: 47,Issue: 5,Page: 1769-1784
Authors:  Li C.;  Chen T.;  Zhou H.;  Zhang C.;  Feng Y.;  Tang F.;  Hoi M.P.-M.;  He C.;  Zheng Y.;  Lee S.M.-Y.
Favorite  |  View/Download:2/0  |  Submit date:2018/11/06
Microglia  Neuroinflammation  NF-κB  Nrf2  Schisantherin A  
Cyanidin-3-o-β-Glucoside Induces Megakaryocyte Apoptosis via PI3K/Akt- and MAPKs-Mediated Inhibition of NF-κB Signalling Journal article
Thrombosis and Haemostasis, 2018,Volume: 118,Issue: 7,Page: 1215-1229
Authors:  Ya F.;  Li Q.;  Wang D.;  Xie S.;  Song F.;  Gallant R.C.;  Tian Z.;  Wan J.;  Ling W.;  Yang Y.
Favorite  |  View/Download:6/0  |  Submit date:2018/12/28
anthocyanins  apoptosis  Cy-3-g  megakaryocyte  thrombopoiesis