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Oral Delivery of Puerarin Nanocrystals To Improve Brain Accumulation and Anti-Parkinsonian Efficacy Journal article
MOLECULAR PHARMACEUTICS, 2019,Volume: 16,Issue: 4,Page: 1444-1455
Authors:  Sha Xiong;  Wei Liu;  Dongli Li;  Xiaojia Chen;  Fang Liu;  Dongsheng Yuan;  Huafeng Pan;  Qi Wang;  Shuhuan Fang;  Tongkai Chen
Favorite | View/Download:12/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2020/01/06
Parkinson’s Disease  Brain Accumulation  Nanocrystals  Oral Delivery  Puerarin  
An Integrated Transfer Learning and Multitask Learning Approach for Pharmacokinetic Parameter Prediction Journal article
Molecular Pharmaceutics, 2019,Volume: 16,Issue: 2,Page: 533-541
Authors:  Ye Z.;  Yang Y.;  Li X.;  Cao D.;  Ouyang D.
Favorite | View/Download:22/0 | TC[WOS]:5 TC[Scopus]:0 | Submit date:2019/02/14
Adme  Deep Learning  Multitask Learning  Pharmacokinetic Parameters  Transfer Learning  
A Synthetic Receptor as a Specific Antidote for Paraquat Poisoning Journal article
THERANOSTICS, 2019,Volume: 9,Issue: 3,Page: 633-645
Authors:  Xiangjun Zhang;  Xiaoqiu Xu;  Shengke Li;  Lanlan Li;  Jianxiang Zhang;  Ruibing Wang
Favorite | View/Download:14/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2020/04/03
Paraquat Toxicity  Cucurbit[7]Uril  Antidote  Detoxification  
Development and application of bio-sample quantification to evaluate stability and pharmacokinetics of inulin-type fructo-oligosaccharides from Morinda Officinalis Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018,Volume: 156,Page: 125-132
Authors:  Liandi Chi;  Lingxiao Chen;  Jiwen Zhang;  Jing Zhao;  Shaoping Li;  Ying Zheng
Favorite | View/Download:24/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date:2018/10/30
Lnulin-type Fructooligosaccharides (Fos)  Morindo Officinalis  Stability  Absorption  Bioavailability  Gut Microbiota  
Analysis of the Literature and Patents on Solid Dispersions from 1980 to 2015 Journal article
MOLECULES, 2018,Volume: 23,Issue: 7
Authors:  Zhang, Jinglu;  Han, Run;  Chen, Weijie;  Zhang, Weixiang;  Li, Ying;  Ji, Yuanhui;  Chen, Lijiang;  Pan, Hao;  Yang, Xinggang;  Pan, Weisan;  Ouyang, Defang
Favorite | View/Download:22/0 | TC[WOS]:6 TC[Scopus]:0 | Submit date:2018/10/30
Solid Dispersion  Big Data  Literature  Patent  Scientific Knowledge Mapping  Citespace  
Main active constituent identification in Guanxinjing capsule, a traditional Chinese medicine, for the treatment of coronary heart disease complicated with depression Journal article
ACTA PHARMACOLOGICA SINICA, 2018,Volume: 39,Issue: 6,Page: 975-987
Authors:  Zhang, Yan-qiong;  Guo, Qiu-yan;  Li, Qiu-yue;  Ren, Wei-qiong;  Tang, Shi-huan;  Wang, Song-song;  Liang, Ri-xin;  Li, De-feng;  Zhang, Yi;  Xu, Hai-yu;  Yang, Hong-jun
Favorite | View/Download:27/0 | TC[WOS]:10 TC[Scopus]:0 | Submit date:2018/10/30
traditional Chinese medicine  Guanxinjing capsule  coronary heart disease  depression  integrative pharmacology  in silico ADME prediction  target prediction  network analysis  
Multiscale and Multifunctional Emulsions by Host-Guest Interaction-Mediated Self-Assembly Journal article
ACS CENTRAL SCIENCE, 2018,Volume: 4,Issue: 5,Page: 600-605
Authors:  Han, Songling;  Chen, Siyu;  Li, Lanlan;  Li, Jin;  An, Huijie;  Tao, Hui;  Jia, Yi;  Lu, Shan;  Wang, Ruibing;  Zhang, Jianxiang
Favorite | View/Download:37/0 | TC[WOS]:9 TC[Scopus]:0 | Submit date:2018/10/30
Computer-Aided Formulation Design for a Highly Soluble Lutein-Cyclodextrin Multiple-Component Delivery System Journal article
MOLECULAR PHARMACEUTICS, 2018,Volume: 15,Issue: 4,Page: 1664-1673
Authors:  Zhao, Qianqian;  Miriyala, Nikhila;  Su, Yan;  Chen, Weijie;  Gao, Xuejiao;  Shao, Ling;  Yan, Ru;  Li, Haifeng;  Yao, Xiaojun;  Cao, Dongsheng;  Wang, Yitao;  Ouyang, Defang
View | Adobe PDF | Favorite | View/Download:792/60 | TC[WOS]:9 TC[Scopus]:0 | Submit date:2018/10/30
Lutein  Cyclodextrin  Multiple-component System  Molecular Dynamics Simulation  Bioavailability  Computer-aided Formulation Design  
Dual-functional Brij-S20-modified nanocrystal formulation enhances the intestinal transport and oral bioavailability of berberine Journal article
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2018,Volume: 13,Page: 3781-3793
Authors:  Xiong, Wei;  Sang, Wei;  Linghu, Ke Gang;  Zhong, Zhang Feng;  Cheang, Wai San;  Li, Juan;  Hu, Yuan Jia;  Yu, Hua;  Wang, Yi Tao
Favorite | View/Download:161/0 | TC[WOS]:5 TC[Scopus]:0 | Submit date:2018/10/30
Berberine  Poor Water Solubility  Pgp-mediated Drug Efflux  Brij  Nanocrystals  
Flavonoids as modulators of metabolic enzymes and drug transporters Journal article
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 2017,Volume: 1398,Issue: 1,Page: 152-167
Authors:  Miron, Anca;  Aprotosoaie, Ana Clara;  Trifan, Adriana;  Xiao, Jianbo
Favorite | View/Download:25/0 | TC[WOS]:37 TC[Scopus]:0 | Submit date:2018/10/30
Flavonoids  Cytochrome P450 3a4 Enzyme  Organic Anion Transporters  P-glycoprotein  Multidrug Resistance