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Discovery of fused bicyclic derivatives of 1H-pyrrolo[1,2-c]imidazol-1-one as VDR signaling regulators Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2019,Volume: 27,Issue: 17,Page: 3879-3888
Authors:  Bin Xu;  Mo-Yu Ding;  Zhibing Weng;  Zheng-Qing Li;  Feng Li;  Xia Sun;  Qiu-Ling Chen;  Yi-Tao Wang;  Ying Wang;  Guo-Chun Zhou
Favorite  |  View/Download:4/0  |  Submit date:2019/11/22
1h-pyrrolo[1,2-c]Imidazol-1-one  Vitamin d Receptor (Vdr)  Autophagy  Apoptosis  
The anti-inflammatory potential of Portulaca oleracea L. (purslane) extract by partial suppression on NF-kappa B and MAPK activation Journal article
FOOD CHEMISTRY, 2019,Volume: 290,Page: 239-245
Authors:  Lingchao Miao;  Hongxun Tao;  Yu Peng;  Shengpeng Wang;  Zhangfeng Zhong;  Hesham El-Seedi;  Simona Dragan;  Gokhan Zengin;  Wai San Cheang;  Yitao Wang;  Jianbo Xiao
Favorite  |  View/Download:2/0  |  Submit date:2019/11/22
PortuL.ca OL.racea L.  Flavonoids  Lipopolysaccharide  Anti-inflammatory Effects  Nf-κb  Mapk  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
View  |  Adobe PDF(2009Kb)  |  Favorite  |  View/Download:339/49  |  Submit date:2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Polysaccharide PRM3 from Rhynchosia minima root enhances immune function through TLR4-NF-κB pathway Journal article
Biochimica et Biophysica Acta - General Subjects, 2018,Volume: 1862,Issue: 8,Page: 1751-1759
Authors:  Jia X.;  Liang Y.;  Zhang C.;  Wang K.;  Tu Y.;  Chen M.;  Li P.;  Wan J.-B.;  He C.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/27
Immunomodulation  NF-κB  Polysaccharide  Rhynchosia minima root  Toll-like receptor 4  
Interference of Quercetin on Astragalus Polysaccharide-Induced Macrophage Activation Journal article
MOLECULES, 2018,Volume: 23,Issue: 7
Authors:  Li, Zhi-Peng;  Liu, Hong-Bing;  Zhang, Quan-Wei;  Li, Li-Feng;  Bao, Wan-Rong;  Ma, Dik-Lung;  Leung, Chung-Hang;  Bian, Zhao-Xiang;  Lu, Ai-Ping;  Han, Quan-Bin
View  |  Adobe PDF(1815Kb)  |  Favorite  |  View/Download:128/6  |  Submit date:2018/10/30
astragalus polysaccharide  quercetin  cytokines  macrophage  foods  
Cyanidin-3-o-β-Glucoside Induces Megakaryocyte Apoptosis via PI3K/Akt- and MAPKs-Mediated Inhibition of NF-κB Signalling Journal article
Thrombosis and Haemostasis, 2018,Volume: 118,Issue: 7,Page: 1215-1229
Authors:  Ya F.;  Li Q.;  Wang D.;  Xie S.;  Song F.;  Gallant R.C.;  Tian Z.;  Wan J.;  Ling W.;  Yang Y.
Favorite  |  View/Download:7/0  |  Submit date:2018/12/28
anthocyanins  apoptosis  Cy-3-g  megakaryocyte  thrombopoiesis  
Cyanidin-3-o-beta-Glucoside Induces Megakaryocyte Apoptosis via PI3K/Akt- and MAPKs-Mediated Inhibition of NF-kappa B Signalling Journal article
THROMBOSIS AND HAEMOSTASIS, 2018,Volume: 118,Issue: 7,Page: 1215-1229
Authors:  Ya, Fuli;  Li, Qing;  Wang, Dongliang;  Xie, Shuangfeng;  Song, Fenglin;  Gallant, Reid C.;  Tian, Zezhong;  Wan, Jianbo;  Ling, Wenhua;  Yang, Yan
Favorite  |  View/Download:10/0  |  Submit date:2018/10/30
megakaryocyte  thrombopoiesis  anthocyanins  Cy-3-g  apoptosis  
Small Molecule Pin1 Inhibitor Blocking NF-B Signaling in Prostate Cancer Cells Journal article
CHEMISTRY-AN ASIAN JOURNAL, 2018,Volume: 13,Issue: 3,Page: 275-279
Authors:  Wu, Ke-Jia;  Zhong, Hai-Jing;  Yang, Guanjun;  Wu, Chun;  Huang, Jie-Min;  Li, Guodong;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite  |  View/Download:18/0  |  Submit date:2018/10/30
enzymes  natural products  Pin1  protein-protein interactions  virtual screening  
Discovery and preliminary SAR of 14-aryloxy-andrographolide derivatives as antibacterial agents with immunosuppressant activity Journal article
RSC ADVANCES, 2018,Volume: 8,Issue: 17,Page: 9440-9456
Authors:  Li, Feng;  Li, Xiao-Min;  Sheng, Dekuan;  Chen, Shao-Ru;  Nie, Xin;  Liu, Zhuyun;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Wang, Ying;  Zhou, Guo-Chun
View  |  Adobe PDF(583Kb)  |  Favorite  |  View/Download:150/10  |  Submit date:2018/10/30
Siegesbeckia pubescens Makino inhibits Pam3CSK4-induced inflammation in RAW 264.7 macrophages through suppressing TLR1/TLR2-mediated NF-ΚB activation Journal article
Chinese Medicine (United Kingdom), 2018,Volume: 13,Issue: 1
Authors:  Sang W.;  Zhong Z.;  Linghu K.;  Xiong W.;  Tse A.K.W.;  Cheang W.S.;  Yu H.;  Wang Y.
Favorite  |  View/Download:6/0  |  Submit date:2018/10/31
Inflammation  Nf-κb  Pam3csk4  Siegesbeckia Pubescens Makino  Toll-like Receptor 1/2