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Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View  |  Adobe PDF(2766Kb)  |  Favorite  |  View/Download：109/4  |  Submit date：2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Roles of Nitric Oxide Synthase Isoforms in Neurogenesis Journal article
MOLECULAR NEUROBIOLOGY, 2017,Volume: 55,Issue: 3,Page: 2645-2652
Authors:  Chong, Cheong-Meng;  Ai, Nana;  Ke, Minjing;  Tan, Yuan;  Huang, Zhijian;  Li, Yong;  Lu, Jia-Hong;  Ge, Wei;  Su, Huanxing
Favorite  |  View/Download：16/0  |  Submit date：2018/10/30
Nitric Oxide  Nitric Oxide Synthase  Neural Stem Cells  Proliferation  Neurogenesis  
Calycosin and Formononetin Induce Endothelium-Dependent Vasodilation by the Activation of Large-Conductance Ca2+-Activated K+ Channels (BKCa) Journal article
Evidence-based Complementary and Alternative Medicine, 2016,Volume: 2016
Authors:  Tseng H.H.L.;  Vong C.T.;  Leung G.P.-H.;  Seto S.W.;  Kwan Y.W.;  Lee S.M.-Y.;  Hoi M.P.M.
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Sunitinib produces neuroprotective effect via inhibiting nitric oxide overproduction Journal article
CNS Neuroscience and Therapeutics, 2014,Volume: 20,Issue: 3,Page: 244-252
Authors:  Cui W.;  Zhang Z.-J.;  Hu S.-Q.;  Mak S.-H.;  Xu D.-P.;  Choi C.-L.;  Wang Y.-Q.;  Tsim W.-K.;  Lee M.-Y.;  Rong J.-H.;  Han Y.-F.
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Cancer  Neuroprotection  Nitric Oxide  Nitric Oxide Synthase  Receptor Tyrosine Kinase  Sunitinib  
The anti-cancer agent SU4312 unexpectedly protects against MPP+- induced neurotoxicity via selective and direct inhibition of neuronal NOS Journal article
British Journal of Pharmacology, 2013,Volume: 168,Issue: 5,Page: 1201
Authors:  Cui W.;  Zhang Z.;  Li W.;  Hu S.;  Mak S.;  Zhang H.;  Han R.;  Yuan S.;  Li S.;  Sa F.;  Xu D.;  Lin Z.;  Zuo Z.;  Rong J.;  Ma E.D.-L.;  Choi T.C.;  Lee S.M.;  Han Y.
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Angiogenesis  Mpp++++  Neuronal Nos  Neuroprotection  Parkinson's Disease  Su4312  
Neuroprotective effects of Astragaloside IV in 6-hydroxydopamine-treated primary nigral cell culture Journal article
Neurochemistry International, 2009,Volume: 55,Issue: 6,Page: 414-422
Authors:  Chan W.-S.;  Durairajan S.S.K.;  Lu J.-H.;  Wang Y.;  Xie L.-X.;  Kum W.-F.;  Koo I.;  Yung K.K.L.;  Li M.
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6-Hydroxydopamine  Astragaloside IV  Nigral primary cell cultures  Nitric oxide synthase  Parkinson's disease  Tyrosine hydroxylase