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Key Molecules and Pathways Underlying Sporadic Amyotrophic Lateral Sclerosis: Integrated Analysis on Gene Expression Profiles of Motor Neurons
Journal article
Frontiers in Genetics, 2020,Volume: 11
Authors:
Lin,Jianing
;
Huang,Pian
;
Chen,Weineng
;
Ye,Chenghui
;
Su,Huanxing
;
Yao,Xiaoli
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View/Download:0/0
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2021/03/01
bioinformatics analysis
FN1 gene
gene expression profiles
motor neurons
sporadic amyotrophic lateral sclerosis
An Isoquinolinium Dual Inhibitor of Cholinesterases and Amyloid β Aggregation Mitigates Neuropathological Changes in a Triple-Transgenic Mouse Model of Alzheimer's Disease
Journal article
ACS Chemical Neuroscience, 2020,Volume: 11,Issue: 20,Page: 3346-3357
Authors:
Ju,Yaojun
;
Chakravarty,Harapriya
;
Tam,Kin Yip
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View/Download:0/0
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2021/03/04
Alzheimer's disease
amyloid beta
cholinesterase
dual inhibition
Oxyphylla a promotes degradation of α-synuclein for neuroprotection via activation of immunoproteasome
Journal article
Aging and Disease, 2020,Volume: 11,Issue: 3,Page: 559-574
Authors:
Zhou,Hefeng
;
Li,Shengnan
;
Li,Chuwen
;
Yang,Xuanjun
;
Li,Haitao
;
Zhong,Hanbing
;
Lu,Jia Hong
;
Lee,Simon Ming Yuen
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View/Download:0/0
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TC[WOS]:
1
TC[Scopus]:
1
|
Submit date:2021/03/01
Degradation
Neuroprotection
Parkinson's disease
Proteasome
α-synuclein
Transcriptome analysis of peripheral whole blood identifies crucial lncRNAs implicated in childhood asthma
Journal article
BMC Medical Genomics, 2020,Volume: 13,Issue: 1
Authors:
Zheng P.
;
Huang C.
;
Leng D.
;
Sun B.
;
Zhang X.D.
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TC[WOS]:
0
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Submit date:2021/03/03
Childhood asthma
Deep RNA-sequencing
Long non-coding RNAs
Transcriptome
Tetramethylpyrazine Analogue T-006 Promotes the Clearance of Alpha-synuclein by Enhancing Proteasome Activity in Parkinson’s Disease Models
Journal article
Neurotherapeutics, 2019,Volume: 16,Issue: 4,Page: 1225-1236
Authors:
Zhou,Hefeng
;
Shao,Min
;
Guo,Baojian
;
Li,Chuwen
;
Lu,Yucong
;
Yang,Xuanjun
;
ShengnanLi,
;
Li,Haitao
;
Zhu,Qi
;
Zhong,Hanbing
;
Wang,Yuqiang
;
Zhang,Zaijun
;
Lu,Jiahong
;
Lee,Simon Ming Yuen
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View/Download:0/0
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TC[WOS]:
7
TC[Scopus]:
7
|
Submit date:2021/03/01
Degradation
LMP7
Parkinson’s disease
Proteasome activity
α-synuclein
Natural alkaloid harmine promotes degradation of alpha-synuclein via PKA-mediated ubiquitin-proteasome system activation
Journal article
Phytomedicine, 2019,Volume: 61
Authors:
Cai,Cui Zan
;
Zhou,He Feng
;
Yuan,Ning Ning
;
Wu,Ming Yue
;
Lee,Simon Ming Yuen
;
Ren,Jiao Yan
;
Su,Huan Xing
;
Lu,Jin Jian
;
Chen,Xiu Ping
;
Li,Min
;
Tan,Jie Qiong
;
Lu,Jia Hong
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View/Download:0/0
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TC[WOS]:
6
TC[Scopus]:
7
|
Submit date:2021/03/01
-synuclein
Harmine
Parkinson's disease
Protein kinase A
Ubiquitin-proteasome system
Canthin-6-One Accelerates Alpha-Synuclein Degradation by Enhancing UPS Activity: Drug Target Identification by CRISPR-Cas9 Whole Genome-Wide Screening Technology
Journal article
FRONTIERS IN PHARMACOLOGY, 2019
Authors:
Ning-Ning Yuan
;
Cui-Zan Cai
;
Ming-Yue Wu
;
Qi Zhu
;
HuanXing Su
;
Min Li
;
JiaoYan Ren
;
Jie-Qiong Tan
;
Jia-Hong Lu
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View/Download:33/0
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TC[WOS]:
4
TC[Scopus]:
6
|
Submit date:2020/04/14
Canthin-6-one
Parkinson’s Disease
Alpha-synuclein
Ubiquitin-proteasome-system
Crispr/cas9
Rpn2/psmd1
Pka
Tetramethylpyrazine Analogue T-006 Exerts Neuroprotective Effects against 6-Hydroxydopamine-Induced Parkinson's Disease In Vitro and In Vivo
Journal article
Oxidative Medicine and Cellular Longevity, 2019,Volume: 2019
Authors:
Zhou,Hefeng
;
Shao,Min
;
Yang,Xuanjun
;
Li,Chuwen
;
Cui,Guozhen
;
Gao,Cheng
;
Di,Lijun
;
Zhong,Hanbing
;
Wang,Yuqiang
;
Zhang,Zaijun
;
Lee,Simon Ming Yuen
Favorite
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View/Download:0/0
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TC[WOS]:
4
TC[Scopus]:
4
|
Submit date:2021/03/01
Vascular endothelial growth factor gene transfer therapy for coronary artery disease: A systematic review and meta-analysis
Journal article
CARDIOVASCULAR THERAPEUTICS, 2018,Volume: 36,Issue: 5
Authors:
Yuan, Rong
;
Xin, Qiqi
;
Shi, Weili
;
Liu, Wei
;
Lee, Simon-M.
;
Hoi, Puiman
;
Li, Lin
;
Zhao, Jun
;
Cong, Weihong
;
Chen, Keji
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View/Download:598/23
|
TC[WOS]:
3
TC[Scopus]:
3
|
Submit date:2018/10/30
Angina Pectoris
Angiogenesis Inducing Agents
Coronary Artery Disease
Genetic Therapy
Myocardial Ischemia
Vascular Endothelial Growth Factor
Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease
Journal article
ORPHANET JOURNAL OF RARE DISEASES, 2018,Volume: 13
Authors:
Vu, Mylinh
;
Li, Rong
;
Baskfield, Amanda
;
Lu, Billy
;
Farkhondeh, Atena
;
Gorshkov, Kirill
;
Motabar, Omid
;
Beers, Jeanette
;
Chen, Guokai
;
Zou, Jizhong
;
Espejo-Mojica, Angela J.
;
Rodriguez-Lopez, Alexander
;
Almeciga-Diaz, Carlos J.
;
Barrera, Luis A.
;
Jiang, Xuntian
;
Ory, Daniel S.
;
Marugan, Juan J.
;
Zheng, Wei
Favorite
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View/Download:90/0
|
TC[WOS]:
11
TC[Scopus]:
11
|
Submit date:2018/10/30
Tay-sachs Disease
Induced Pluripotent Stem Cells
Neural Stem Cells
Cyclodextrin
Hp Beta Cd
Delta-tocopherol
Enzyme Replacement Therapy
Hexosaminidase a
Gm2 Gangliosidosis
High Throughput Screening
Drug Discovery