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Hydroxyurea Facilitates Manifestation of Disease Relevant Phenotypes in Patients-Derived IPSCs-Based Modeling of Late-Onset Parkinson’s Disease Journal article
AGING AND DISEASE, 2019,Volume: 10,Issue: 5,Page: 1037-1048
Authors:  Yuan Tan;  Minjing Ke;  Zhijian Huang;  Cheong-Meng Chong;  Xiaotong Cen;  Jia-Hong Lu;  Xiaoli Yao;  Dajiang Qin;  Huanxing Su
Favorite | View/Download:16/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2020/04/08
Disease Phenotypes  Er Stress  Induced Pluripotentstem Cells  Parkinson’s Disease  Hydroxyurea  
N-Propargyl Caffeamide (PACA) Ameliorates Dopaminergic Neuronal Loss and Motor Dysfunctions in MPTP Mouse Model of Parkinson’s Disease and in MPP+-Induced Neurons via Promoting the Conversion of proNGF to NGF Journal article
Molecular Neurobiology, 2018,Volume: 55,Issue: 3,Page: 2258-2267
Authors:  Luo D.;  Zhao J.;  Cheng Y.;  Lee S.M.-Y.;  Rong J.
Favorite | View/Download:4/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2018/11/06
ERK1/2  N-propargyl caffeamide (PACA)  Neuroprotection  NGF/TrkA pathway  Parkinson’s disease  PI3K/Akt  
N-Propargyl Caffeamide (PACA) Ameliorates Dopaminergic Neuronal Loss and Motor Dysfunctions in MPTP Mouse Model of Parkinson's Disease and in MPP+-Induced Neurons via Promoting the Conversion of proNGF to NGF Journal article
MOLECULAR NEUROBIOLOGY, 2018,Volume: 55,Issue: 3,Page: 2258-2267
Authors:  Luo, Dan;  Zhao, Jia;  Cheng, Yuanyuan;  Lee, Simon Ming-Yuen;  Rong, Jianhui
Favorite | View/Download:13/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2018/10/30
Parkinson's disease  Neuroprotection  N-propargyl caffeamide (PACA)  NGF/TrkApathway  PI3K/Akt  ERK1/2  
N-Propargyl Caffeamide (PACA) Ameliorates Dopaminergic Neuronal Loss and Motor Dysfunctions in MPTP Mouse Model of Parkinson's Disease and in MPP+-Induced Neurons via Promoting the Conversion of proNGF to NGF Journal article
MOLECULAR NEUROBIOLOGY, 2018,Volume: 55,Issue: 3,Page: 2258-2267
Authors:  Luo, Dan;  Zhao, Jia;  Cheng, Yuanyuan;  Lee, Simon Ming-Yuen;  Rong, Jianhui
Favorite | View/Download:11/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2018/10/31
Parkinson's disease  Neuroprotection  N-propargyl caffeamide (PACA)  NGF/TrkApathway  PI3K/Akt  ERK1/2  
N-Propargyl Caffeamide (PACA) Ameliorates Dopaminergic Neuronal Loss and Motor Dysfunctions in MPTP Mouse Model of Parkinson's Disease and in MPP+-Induced Neurons via Promoting the Conversion of proNGF to NGF Journal article
MOLECULAR NEUROBIOLOGY, 2018,Volume: 55,Issue: 3,Page: 2258-2267
Authors:  Luo, Dan;  Zhao, Jia;  Cheng, Yuanyuan;  Lee, Simon Ming-Yuen;  Rong, Jianhui
Favorite | View/Download:17/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2018/10/31
Parkinson's disease  Neuroprotection  N-propargyl caffeamide (PACA)  NGF/TrkApathway  PI3K/Akt  ERK1/2  
N-Propargyl Caffeamide (PACA) Ameliorates Dopaminergic Neuronal Loss and Motor Dysfunctions in MPTP Mouse Model of Parkinson's Disease and in MPP+-Induced Neurons via Promoting the Conversion of proNGF to NGF Journal article
MOLECULAR NEUROBIOLOGY, 2018,Volume: 55,Issue: 3,Page: 2258-2267
Authors:  Luo, Dan;  Zhao, Jia;  Cheng, Yuanyuan;  Lee, Simon Ming-Yuen;  Rong, Jianhui
Favorite | View/Download:11/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2018/10/30
Parkinson's disease  Neuroprotection  N-propargyl caffeamide (PACA)  NGF/TrkApathway  PI3K/Akt  ERK1/2  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
View | Adobe PDF | Favorite | View/Download:507/10 | TC[WOS]:7 TC[Scopus]:0 | Submit date:2018/10/31
Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Dysbindin-1 Involvement in the Etiology of Schizophrenia Journal article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017,Volume: 18,Issue: 10
Authors:  Wang, Haitao;  Xu, Jiangping;  Lazarovici, Philip;  Zheng, Wenhua
Favorite | View/Download:14/0 | TC[WOS]:6 TC[Scopus]:0 | Submit date:2018/10/30
schizophrenia  dysbindin-1  susceptibility gene  neurotransmitter release  neurite outgrowth  
ROCK in CNS: Different Roles of Isoforms and Therapeutic Target for Neurodegenerative Disorders Journal article
CURRENT DRUG TARGETS, 2017,Volume: 18,Issue: 4,Page: 455-462
Authors:  Chong, Cheong-Meng;  Ai, Nana;  Lee, Simon Ming-Yuen
Favorite | View/Download:28/0 | TC[WOS]:14 TC[Scopus]:0 | Submit date:2018/10/30
Axonal Regeneration  Central Nervous System  Fasudil  Isoforms  Limk  Neurodegenerative Diseases  Rock  
Neuroprotection against glutamate-induced excitotoxicity and induction of neurite outgrowth by T-006, a novel multifunctional derivative of tetramethylpyrazine in neuronal cell models Journal article
Neurochemistry International, 2016,Volume: 99,Page: 194-205
Authors:  Xu D.;  Chen H.;  Mak S.;  Hu S.;  Tsim K.W.K.;  Hu Y.;  Sun Y.;  Zhang G.;  Wang Y.;  Zhang Z.;  Han Y.
Favorite | View/Download:3/0 | TC[WOS]:9 TC[Scopus]:0 | Submit date:2018/12/28
Alzheimer's disease  Excitotoxicity  Neurite outgrowth  Neuroprotection  Tetramethylpyrazine derivative