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A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of N-Methyl-D-aspartate Receptor Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Hu, Shengquan;  Hu, Huihui;  Mak, Shinghung;  Cui, Guozhen;  Lee, Mingyuen;  Shan, Luchen;  Wang, Yuqiang;  Lin, Huangquan;  Zhang, Zaijun;  Han, Yifan
Favorite | View/Download:23/0 | TC[WOS]:6 TC[Scopus]:0 | Submit date:2018/10/30
Alzheimer's disease  tetramethylpyrazine derivative  NMDA receptor  neuroprotection  oxidative stress  GSK3 beta  
Adjunctive memantine for schizophrenia: A meta-analysis of randomized, double-blind, placebo-controlled trials Journal article
Psychological Medicine, 2018,Volume: 48,Issue: 1,Page: 72-81
Authors:  Zheng W.;  Li X.-H.;  Yang X.-H.;  Cai D.-B.;  Ungvari G.S.;  Ng C.H.;  Wang S.-B.;  Wang Y.-Y.;  Ning Y.-P.;  Xiang Y.-T.
Favorite | View/Download:5/0 | TC[WOS]:9 TC[Scopus]:0 | Submit date:2018/12/18
Memantine  Meta-analysis  Negative Symptoms  Nmda Receptor Antagonists  Schizophrenia  
H2O2 attenuates IGF-1R tyrosine phosphorylation and its survival signaling properties in neuronal cells via NR2B containing NMDA receptor Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 39,Page: 65313-65328
Authors:  Zeng, Zhiwen;  Wang, Dejun;  Gaur, Uma;  Liao Rifang;  Wang, Haitao;  Zheng, Wenhua
Favorite | View/Download:13/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2018/10/30
H2o2  Sh-sy5y  Nr2b  Nmda  Igf-1r  
Chemically bonding of amantadine with gardenamide A enhances the neuroprotective effects against corticosterone-induced insults in PC12 cells Journal article
International Journal of Molecular Sciences, 2015,Volume: 16,Issue: 9,Page: 22795-22810
Authors:  Zhao J.;  Peng L.;  Zheng W.;  Wang R.;  Zhang L.;  Yang J.;  Chen H.
Favorite | View/Download:4/0 | TC[WOS]:7 TC[Scopus]:0 | Submit date:2018/12/21
Amantadine  eNOS  Gardenamide A  Neuroprotection  NMDA  nNOS  
H-1 nuclear magnetic resonance based-metabolomic characterization of Peucedani Radix and simultaneous determination of praeruptorin A and praeruptorin B Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014,Volume: 93,Issue: SI,Page: 86-94
Authors:  Song, Yue-Lin;  Jing, Wang-Hui;  Chen, Yan-Gan;  Yuan, Yun-Fei;  Yan, Ru;  Wang, Yi-Tao
View | Adobe PDF | Favorite | View/Download:502/26 | TC[WOS]:15 TC[Scopus]:0 | Submit date:2018/11/01
Peucedani Radix  Metabolomic Profile  Quantitative H-1 Nmr  Praeruptorin a  Praeruptorin b  
In silico target fishing for the potential targets and molecular mechanisms of baicalein as an antiparkinsonian agent: Discovery of the protective effects on nmda receptor-mediated neurotoxicity Journal article
Chemical Biology and Drug Design, 2013,Volume: 81,Issue: 6,Page: 675
Authors:  Gao L.;  Fang J.-S.;  Bai X.-Y.;  Zhou D.;  Wang Y.-T.;  Liu A.-L.;  Du G.-H.
Favorite | View/Download:6/0 | TC[WOS]:12 TC[Scopus]:0 | Submit date:2018/10/31
Baicalein  In Silico  N-methyl-d-aspartic Acid  Neurotoxicity  Parkinson's Disease  Target Fishing  
Glutamate attenuates IGF-1 receptor tyrosine phosphorylation in mouse brain: Possible significance in ischemic brain damage Journal article
Neuroscience Research, 2012,Volume: 74,Issue: 3-4,Page: 290-297
Authors:  Sun C.;  Meng Q.;  Zhang L.;  Wang H.;  Quirion R.;  Zheng W.
Favorite | View/Download:3/0 | TC[WOS]:15 TC[Scopus]:0 | Submit date:2018/12/21
Brain ischemia  Glutamate  IGF-1  NMDA receptor  Tyrosine phosphorylation  
Hydrogen peroxide attenuates the prosurvival signaling of insulin-like growth factor-1 through two pathways Journal article
NeuroReport, 2012,Volume: 23,Issue: 13,Page: 768-773
Authors:  Sun C.;  Wang D.;  Zheng W.
Favorite | View/Download:2/0 | TC[WOS]:7 TC[Scopus]:0 | Submit date:2018/12/21
antioxidant  insulin-like growth factor-1  MK-801  N-methyl-D-aspartate receptors  oxidative stress  Trolox  
Glutamate acting on N-methyl-D-aspartate receptors attenuates insulin-like growth factor-1 receptor tyrosine phosphorylation and Its survival signaling properties in rat hippocampal neurons Journal article
Journal of Biological Chemistry, 2009,Volume: 284,Issue: 2,Page: 855-861
Authors:  Zheng W.-H.;  Quirion R.
Favorite | View/Download:5/0 | TC[WOS]:44 TC[Scopus]:0 | Submit date:2018/12/21
Mitochondrial proteomic analysis and characterization of the intracellular mechanisms of bis(7)-tacrine in protecting against glutamate-induced excitotoxicity in primary cultured neurons Journal article
JOURNAL OF PROTEOME RESEARCH, 2007,Volume: 6,Issue: 7,Page: 2435-2446
Authors:  Hongjun Fu;  Wenming Li;  Yulin Liu;  Yuanzhi Lao;  Wei Liu;  Cheng Chen;  Hua Yu;  Nelson T. K. Lee;  Donald C. Chang;  Peng Li;  Yuanping Pang;  Karl W. K. Tsim;  Mingtao Li;  Yifan Han
Favorite | View/Download:69/0 | TC[WOS]:26 TC[Scopus]:0 | Submit date:2020/03/12
Bis(7)-tacrine  Glutamate  Mitochondria  Cerebellar Granule Neurons  Two-dimensional Differential In-gel Electrophoresis  Maldi-tof/ms