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Structure-based identification of a NEDD8-activating enzyme inhibitor via drug repurposing Journal article
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018,Volume: 143,Page: 1021-1027
Authors:  Wu, Ke-Jia;  Zhong, Hai-Jing;  Li, Guodong;  Liu, Chenfu;  Wang, Hui-Min David;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite | View/Download:28/0 | TC[WOS]:25 TC[Scopus]:31 | Submit date:2018/10/30
Drug Repurposing  Mitoxantrone  Nedd8  Ubiquitin  
A Rhodium(III) Complex as an Inhibitor of Neural Precursor Cell Expressed, Developmentally Down-Regulated 8-Activating Enzyme with in Vivo Activity against Inflammatory Bowel Disease Journal article
JOURNAL OF MEDICINAL CHEMISTRY, 2017,Volume: 60,Issue: 1,Page: 497-503
Authors:  Zhong, Hai-Jing;  Wang, Wanhe;  Kang, Tian-Shu;  Yan, Hui;  Yang, Yali;  Xu, Lipeng;  Wang, Yuqiang;  Ma, Dik-Lung;  Leung, Chung-Hang
View | Adobe PDF | Favorite | View/Download:543/22 | TC[WOS]:36 TC[Scopus]:40 | Submit date:2018/10/30
Discovery of deoxyvasicinone derivatives as inhibitors of NEDD8-activating enzyme Journal article
Methods, 2015,Volume: 71,Issue: C,Page: 71-76
Authors:  Zhong H.-J.;  Leung K.-H.;  Lin S.;  Chan D.S.-H.;  Han Q.-B.;  Chan S.L.-F.;  Ma D.-L.;  Leung C.-H.
Favorite | View/Download:6/0 | TC[WOS]:11 TC[Scopus]:10 | Submit date:2018/11/06
Deoxyvasicinone  Drug Discovery  Nedd8  Pharmacophore  Ubiquitin-like