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MK2 mediates macrophage activation and acute lung injury by regulating let-7e miRNA Journal article
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2018,Volume: 315,Issue: 3,Page: L371-L381
Authors:  Wu, Yaxian;  He, Huiqiong;  Ding, Yunhe;  Liu, Sirui;  Zhang, Depeng;  Wang, Jun;  Jiang, Hongchao;  Zhang, Dan;  Sun, Lei;  Ye, Richard D.;  Qian, Feng
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acute lung injury  let-7e  lipopolysaccharides  macrophage  MAPK-activated protein kinase 2  miRNA  MK2  
Structure-based identification of a NEDD8-activating enzyme inhibitor via drug repurposing Journal article
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018,Volume: 143,Page: 1021-1027
Authors:  Wu, Ke-Jia;  Zhong, Hai-Jing;  Li, Guodong;  Liu, Chenfu;  Wang, Hui-Min David;  Ma, Dik-Lung;  Leung, Chung-Hang
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Drug repurposing  Mitoxantrone  NEDD8  Ubiquitin  
Nedd8 modification of Cullin-5 regulates lipopolysaccharide-induced acute lung injury Journal article
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2017,Volume: 313,Issue: 1,Page: L104-L114
Authors:  Zhu, Ziyan;  Sun, Lei;  Hao, Rui;  Jiang, Hongchao;  Qian, Feng;  Ye, Richard D.
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Cullin-5  macrophage  Nedd8  acute lung injury  
A Rhodium(III) Complex as an Inhibitor of Neural Precursor Cell Expressed, Developmentally Down-Regulated 8-Activating Enzyme with in Vivo Activity against Inflammatory Bowel Disease Journal article
JOURNAL OF MEDICINAL CHEMISTRY, 2017,Volume: 60,Issue: 1,Page: 497-503
Authors:  Zhong, Hai-Jing;  Wang, Wanhe;  Kang, Tian-Shu;  Yan, Hui;  Yang, Yali;  Xu, Lipeng;  Wang, Yuqiang;  Ma, Dik-Lung;  Leung, Chung-Hang
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Discovery of deoxyvasicinone derivatives as inhibitors of NEDD8-activating enzyme Journal article
Methods, 2015,Volume: 71,Issue: C,Page: 71-76
Authors:  Zhong H.-J.;  Leung K.-H.;  Lin S.;  Chan D.S.-H.;  Han Q.-B.;  Chan S.L.-F.;  Ma D.-L.;  Leung C.-H.
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Deoxyvasicinone  Drug discovery  NEDD8  Pharmacophore  Ubiquitin-like  
Natural products as inhibitorsof the ubiquitin-/ubiquitin-likeprotein-proteasome pathway Book
2012
Authors:  Ma D.-L.;  Pui-Yan Ma V.;  Shiu-Hin Chan D.;  Leung K.-H.;  Zhong H.-J.;  Leung C.-H.
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