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Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors Journal article
JOURNAL OF PROTEOME RESEARCH, 2018,Volume: 17,Issue: 9,Page: 3012-3021
Authors:  Zhang, Wen;  Hu, Xiaohui;  Zhou, Wei;  Tam, Kin Yip
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aerobic glycolysis  AZD7545  dichloroacetate  LC-MS/MS  pyruvate dehydrogenase kinases  cancer metabolism  
Triggering of cancer cell cycle arrest by a novel scorpion venom-derived peptide-Gonearrestide Journal article
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2018,Volume: 22,Issue: 9,Page: 4460-4473
Authors:  Li, Bin;  Lyu, Peng;  Xi, Xinping;  Ge, Lilin;  Mahadevappa, Ravikiran;  Shaw, Chris;  Kwok, Hang Fai
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Anticancer Mechanism  Binding Sites  Ms  Ms Proteome  Ngs Transcriptome  Signalling Pathways  Venom Library  
Fast identification of anticancer constituents in Forsythiae Fructus based on metabolomics approaches Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018,Volume: 154,Page: 312-320
Authors:  Bao, Jiaolin;  Ding, Ren-Bo;  Jia, Xuejing;  Liang, Yeer;  Liu, Fang;  Wang, Kai;  Zhang, Chao;  Li, Peng;  Wang, Yitao;  Wan, Jian-Bo;  He, Chengwei
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Forsythiae Fructus  Anticancer  Metabolomics  Multivariate Data Analysis  B16-f10 Melanoma  
Integrated work-flow for quantitative metabolome profiling of plants, Peucedani Radix as a case Journal article
ANALYTICA CHIMICA ACTA, 2017,Volume: 953,Page: 40-47
Authors:  Song, Yuelin;  Song, Qingqing;  Liu, Yao;  Li, Jun;  Wan, Jian-Bo;  Wang, Yitao;  Jiang, Yong;  Tu, Pengfei
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Quantitative Metabolome  Integrated Work-flow  Offline Two Dimensional Liquid  Chromatography  Linear Range  Peucedani Radix  Isomer  
Discovery, synthesis, and functional characterization of a novel neuroprotective natural product from the fruit of alpinia oxyphylla for use in Parkinson's disease through LC/MS-based multivariate data analysis-guided fractionation Journal article
Journal of Proteome Research, 2016,Volume: 15,Issue: 8,Page: 2595-2606
Authors:  Li G.;  Zhang Z.;  Quan Q.;  Jiang R.;  Szeto S.S.W.;  Yuan S.;  Wong W.-T.;  Lam H.H.C.;  Lee S.M.-Y.;  Chu I.K.
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natural products  neuroprotective  NRF2  Parkinson's disease  proteomics  
A versatile reversed phase-strong cation exchange-reversed phase (RP-SCX-RP) multidimensional liquid chromatography platform for qualitative and quantitative shotgun proteomics Journal article
Analyst, 2015,Volume: 140,Issue: 4,Page: 1237-1252
Authors:  Law H.C.H.;  Kong R.P.W.;  Szeto S.S.W.;  Zhao Y.;  Zhang Z.;  Wang Y.;  Li G.;  Quan Q.;  Lee S.M.Y.;  Lam H.C.;  Chu I.K.
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H-1 nuclear magnetic resonance based-metabolomic characterization of Peucedani Radix and simultaneous determination of praeruptorin A and praeruptorin B Journal article
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2014,Volume: 93,Issue: SI,Page: 86-94
Authors:  Song, Yue-Lin;  Jing, Wang-Hui;  Chen, Yan-Gan;  Yuan, Yun-Fei;  Yan, Ru;  Wang, Yi-Tao
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Peucedani Radix  Metabolomic Profile  Quantitative H-1 Nmr  Praeruptorin a  Praeruptorin b  
Advances in MALDI mass spectrometry in clinical diagnostic applications. Book chapter
出自: Chemical Diagnostics:From Bench to Bedside:Springer, Berlin, Heidelberg, 2014, 页码: 139-175
Authors:  Ng, Eddy W. Y.;  Wong, Melody Y. M.;  Poon, Terence C. W.
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Biomarkers  Clinical Diagnostics  Matrix-assisted Laser Desorption/ionization (Maldi)  Surface Assisted Laser Desorption/ionization (Saldi)  Surface-enhanced Laser Desorption/ionization (Seldi)  Time-of-flight (Tof)  
Combined in vivo imaging and omics approaches reveal metabolism of icaritin and its glycosides in zebrafish larvae Journal article
MOLECULAR BIOSYSTEMS, 2011,Volume: 7,Issue: 7,Page: 2128-2138
Authors:  Li, ZH (Li, Zhen Hua);  Alex, D (Alex, Deepa);  Siu, SO (Siu, Shiu On);  Chu, IK (Chu, Ivan Keung);  Renn, J (Renn, Joerg);  Winkler, C (Winkler, Christoph);  Lou, S (Lou, Shaoke);  Tsui, SKW (Tsui, Stephen Kwok-Wing);  Zhao, HY (Zhao, Hai Yu);  Yan, WR (Yan, Wendy Ru);  Mahady, GB (Mahady, Gail B.);  Li, GH (Li, Guo Hui);  Kwan, YW (Kwan, Yiu Wa);  Wang, YT (Wang, Yi Tao);  Lee, SMY (Lee, Simon Ming-Yuen)
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Animal-models  Flavonoids  Quercetin  Bone  Fluorescence  Absorption  Proteome  Swim  
A magnetic bead-based serum proteomic fingerprinting method for parallel analytical analysis and micropreparative purification Journal article
Electrophoresis, 2010,Volume: 31,Issue: 10,Page: 1721-1730
Authors:  Wong M.Y.M.;  Yu K.O.Y.;  Poon T.C.W.;  Ang I.L.;  Law M.-K.;  Chan K.Y.W.;  Ng E.W.Y.;  Ngai S.-M.;  Sung J.J.Y.;  Chan H.L.Y.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/18
Biomarker  Chromatographic magnetic bead  MALDI-TOF-MS  Plasma proteome  Semi-quantitative proteomic profiling