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Adeno-Associated Virus-Mediated RNAi against Mutant Alleles Attenuates Abnormal Calvarial Phenotypes in an Apert Syndrome Mouse Model Journal article
Molecular Therapy - Nucleic Acids, 2018,Volume: 13,Page: 291-302
Authors:  Luo F.;  Xie Y.;  Wang Z.;  Huang J.;  Tan Q.;  Sun X.;  Li F.;  Li C.;  Liu M.;  Zhang D.;  Xu M.;  Su N.;  Ni Z.;  Jiang W.;  Chang J.;  Chen H.;  Chen S.;  Xu X.;  Deng C.;  Wang Z.;  Du X.;  Chen L.
Favorite  |  View/Download:14/0  |  Submit date:2018/12/13
Adeno-associated Virus  Apert Syndrome  Craniosynostosis  Fgfr2  Molecular Therapy  Rnai  
A user-friendly herbicide derived from photo-responsive supramolecular vesicles Journal article
Nature Communications, 2018,Volume: 9,Issue: 1
Authors:  Gao C.;  Huang Q.;  Lan Q.;  Feng Y.;  Tang F.;  Hoi M.P.M.;  Zhang J.;  Lee S.M.Y.;  Wang R.
Favorite  |  View/Download:27/0  |  Submit date:2018/11/06
Anti-neuroinflammatory effects of SLOH in Aβ-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3β Journal article
Neuroscience Letters, 2018,Volume: 687,Page: 207-215
Authors:  Wu X.;  Kosaraju J.;  Tam K.Y.
Favorite  |  View/Download:0/0  |  Submit date:2018/12/18
3xTg-AD mice  BV-2 cells  GSK-3β  Neuroinflammation  SLOH  
Anti-neuroinflammatory effects of SLOH in A beta-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3 beta Journal article
NEUROSCIENCE LETTERS, 2018,Volume: 687,Page: 207-215
Authors:  Wu, Xiaoli;  Kosaraju, Jayasankar;  Tam, Kin Yip
Favorite  |  View/Download:1/0  |  Submit date:2019/01/17
SLOH  BV-2 cells  3xTg-AD mice  Neuroinflammation  GSK-3 beta  
Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 838,Page: 41-52
Authors:  Yang, Zheng;  Zhang, Shao-Lin;  Hu, Xiaohui;  Tam, Kin Yip
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
Dichloroacetophenone  Epidermal growth factor receptor  Tyrosine kinase inhibitor  Synergism  Hypoxia  Oxidative phosphorylation  
Tetrahydrocurcumin, a major metabolite of curcumin, ameliorates allergic airway inflammation by attenuating Th2 response and suppressing the IL-4Rα-Jak1-STAT6 and Jagged1/Jagged2 -Notch1/Notch2 pathways in asthmatic mice Journal article
Clinical and Experimental Allergy, 2018,Volume: 48,Issue: 11,Page: 1494-1508
Authors:  Chen B.L.;  Chen Y.Q.;  Ma B.H.;  Yu S.F.;  Li L.Y.;  Zeng Q.X.;  Zhou Y.T.;  Wu Y.F.;  Liu W.L.;  Wan J.B.;  Yang Y.;  Li C.W.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/28
airway inflammation  asthma  dietary factor  tetrahydrocurcumin  Th2 response  
Anticancer effects of some novel dichloroacetophenones through the inhibition of pyruvate dehydrogenase kinase 1 Journal article
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2018,Volume: 123,Page: 43-55
Authors:  Zhang, Shao-Lin;  Yang, Zheng;  Hu, Xiaohui;  Chakravarty, Harapriya;  Tam, Kin Yip
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Dichloroacetophenone  Pyruvate Dehydrogenase Kinase  Pyruvate Dehydrogenase Complex  Anticancer Activity  Metabolic Reprogramming  
Self-Supplied Tumor Oxygenation through Separated Liposomal Delivery of H2O2 and Catalase for Enhanced Radio-Immunotherapy of Cancer Journal article
Nano Letters, 2018,Volume: 18,Issue: 10,Page: 6360-6368
Authors:  Song X.;  Xu J.;  Liang C.;  Chao Y.;  Jin Q.;  Wang C.;  Chen M.;  Liu Z.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/27
check-point-blockade immunotherapy  radiotherapy  self-supplied oxygen delivery  Tumor hypoxia  
Serum amyloid A promotes LPS clearance and suppresses LPS-induced inflammation and tissue injury Journal article
EMBO REPORTS, 2018,Volume: 19,Issue: 10
Authors:  Cheng, Ni;  Liang, Yurong;  Du, Xiaoping;  Ye, Richard D.
View  |  Adobe PDF(2278Kb)  |  Favorite  |  View/Download:138/3  |  Submit date:2018/10/30
acute-phase response  inflammation  innate immunity  lipopolysaccharide  serum amyloid A  
Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy Journal article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018,Volume: 57,Issue: 40,Page: 13091-13095
Authors:  Yang, Guan-Jun;  Wang, Wanhe;  Mok, Simon Wing Fai;  Wu, Chun;  Law, Betty Yuen Kwan;  Miao, Xiang-Min;  Wu, Ke-Jia;  Zhong, Hai-Jing;  Wong, Chun-Yuen;  Wong, Vincent Kam Wai;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite  |  View/Download:25/0  |  Submit date:2018/10/30
Drug Discovery  Epigenetics  Medicinal Chemistry  Triple-negative Breast Cancer