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Anti-inflammatory activities of Sigesbeckia glabrescens Makino: combined in vitro and in silico investigations Journal article
CHINESE MEDICINE, 2019,Volume: 14,Issue: 1
Authors:  Zhangfeng Zhong;  Qianru Zhang;  Hongxun Tao;  Wei Sang;  Liao Cui;  Wenan Qiang;  Wai San Cheang;  Yuanjia Hu;  Hua Yu;  Yitao Wang
Favorite  |  View/Download:60/0  |  Submit date:2019/11/22
Sigesbeckia Glabrescens Makino  Infammation  Lipopolysaccharide  Docking  Tlr4  Nf-κb  
Combined transcriptomic and proteomic analysis reveals a diversity of venom-related and toxin-like peptides expressed in the mat anemone Zoanthus natalensis (Cnidaria, Hexacorallia) Journal article
ARCHIVES OF TOXICOLOGY, 2019,Volume: 93,Issue: 6,Page: 1745-1767
Authors:  Qiwen Liao;  Guiyi Gong;  Terence C. W. Poon;  Irene L. Ang;  Kate M. K. Lei;  Shirley Weng In Siu;  Clarence Tsun Ting Wong;  Gandhi Rádis-Baptista;  Simon Ming-Yuen Lee
Favorite  |  View/Download:221/0  |  Submit date:2020/01/16
Cnidaria  Neuroprotection  Proteomic  Transcriptomic  Venom-derived Peptide  Zoantharian  
Novel neurotoxic peptides from Protopalythoa variabilis virtually interact with voltage-gated sodium channel and display anti-epilepsy and neuroprotective activities in zebrafish Journal article
Archives of Toxicology, 2019,Volume: 93,Issue: 1,Page: 189-206
Authors:  Liao Q.;  Li S.;  Siu S.W.I.;  Morlighem J.-E.R.L.;  Wong C.T.T.;  Wang X.;  Radis-Baptista G.;  Lee S.M.-Y.
Favorite  |  View/Download:13/0  |  Submit date:2019/04/04
Anti-epilepsy  Disulfide bond  Neuroactive peptides  Neuroprotection  Protein docking  Voltage-gated sodium ion channel blocker  
Comparative comprehension on the anti-rheumatic Chinese herbal medicine Siegesbeckiae Herba: Combined computational predictions and experimental investigations Journal article
Journal of Ethnopharmacology, 2019,Volume: 228,Page: 200-209
Authors:  Zhang Q.R.;  Zhong Z.F.;  Sang W.;  Xiong W.;  Tao H.X.;  Zhao G.D.;  Li Z.X.;  Ma Q.S.;  Tse A.K.W.;  Hu Y.J.;  Yu H.;  Wang Y.T.
Favorite  |  View/Download:26/0  |  Submit date:2018/12/28
Computational Prediction  Difference  Rheumatoid Arthritis  Siegesbeckiae Herba  Similarity  
Stereoselective interactions of lactic acid enantiomers with HSA: Spectroscopy and docking application Journal article
FOOD CHEMISTRY, 2019,Volume: 270,Page: 429-435
Authors:  Mu, Hongtao;  Chen, Shaohuan;  Liu, Fengyin;  Xiao, Jianbo;  Huang, Hui;  Zhang, Yuhua;  Sun, Yuanming;  Gao, Xiangyang;  Lei, Hongtao;  Yuan, Xuewen
Favorite  |  View/Download:53/0  |  Submit date:2018/10/30
Lactic Acid Isomers  Human Serum Albumin  Fluorescence Spectroscopy  Circular Dichroism  Docking Simulation  
A novel FGFR1-binding peptide attenuates the degeneration ofarticular cartilage in adult mice Journal article
Osteoarthritis and Cartilage, 2018,Volume: 26,Issue: 12,Page: 1733-1743
Authors:  Q. Tan;  B. Chen;  Q. Wang;  W.Xu;  Y.Wang;  Z. Lin;  F.Luo;  S. Huang;  Y.Zhu;  N. Su;  M. Jin;  C.Li;  L. Kuang;  H.Qi;  Z.Ni;  Z. Wang;  X. Luo;  W. Jiang;  H. Chen;  S. Chen;  F.Li;  B. Zhang;  J. Huang;  R. Zhang;  K. Jin;  X.Xu;  C. Deng;  X.Du;  Y. Xie;  L. Chen
Favorite  |  View/Download:24/0  |  Submit date:2018/12/17
Fgfr1  Peptide  Osteoarthritis  Mice  
A novel FGFR1-binding peptide attenuates the degeneration of articular cartilage in adult mice Journal article
Osteoarthritis and Cartilage, 2018,Volume: 26,Issue: 12,Page: 1733-1743
Authors:  Tan Q.;  Chen B.;  Wang Q.;  Xu W.;  Wang Y.;  Lin Z.;  Luo F.;  Huang S.;  Zhu Y.;  Su N.;  Jin M.;  Li C.;  Kuang L.;  Qi H.;  Ni Z.;  Wang Z.;  Luo X.;  Jiang W.;  Chen H.;  Chen S.;  Li F.;  Zhang B.;  Huang J.;  Zhang R.;  Jin K.;  Xu X.;  Deng C.;  Du X.;  Xie Y.;  Chen L.
Favorite  |  View/Download:10/0  |  Submit date:2018/12/17
FGFR1  Mice  Osteoarthritis  Peptide  
Characteristics and molecular determinants of a highly selective and efficient glycyrrhizin-hydrolyzing beta-glucuronidase from Staphylococcus pasteuri 3I10 Journal article
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2018,Volume: 102,Issue: 21,Page: 9193-9205
Authors:  Wei, Bin;  Wang, Pan-Pan;  Yan, Zhi-Xiang;  Yan, Ru
Favorite  |  View/Download:7/0  |  Submit date:2019/01/17
Staphylococcus pasteuri  Bacterial beta-glucuronidase  Glycyrrhizin  Glycyrrhetinic acid  Deglucuronidation  Homology modeling  
A hybrid cuckoo search and differential evolution approach to protein–ligand docking Journal article
International Journal of Molecular Sciences, 2018,Volume: 19,Issue: 10
Authors:  Lin H.;  Siu S.W.I.
Favorite  |  View/Download:3/0  |  Submit date:2019/04/04
Autodock vina  Conformational search  Cuckoo search  CuckooVina  Differential evolution  Metaheuristic  Optimization  PSOvina  Structure-based drug design  
Dihydronortanshinone, a natural product, alleviates LPS-induced inflammatory response through NF-κB, mitochondrial ROS, and MAPK pathways Journal article
Toxicology and Applied Pharmacology, 2018,Volume: 355,Page: 1-8
Authors:  Xiaxia Wu;  Hongwei Gao;  Ying Hou;  Jie Yu;  Wen Sun;  Ying Wang;  Xiaoyan Chen;  Yulin Feng;  Qiong-ming Xu;  Xiuping Chen
Favorite  |  View/Download:26/0  |  Submit date:2018/12/28
Dihydronortanshinone  Inflammation  Lps  Macrophage