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MLKL mediates apoptosis via a mutual regulation with PERK/eIF2α pathway in response to reactive oxygen species generation Journal article
Apoptosis, 2018,Volume: 23,Issue: 9-10,Page: 521-531
Authors:  Cao W.-X.;  Li T.;  Tang Z.-H.;  Zhang L.-L.;  Wang Z.-Y.;  Guo X.;  Su M.-X.;  Chen X.;  Lu J.-J.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/28
Apoptosis  Chelerythrine  Eif2α  Mlkl  Ros  
A rare variant in MLKL confers susceptibility to ApoE ɛ4-negative Alzheimer's disease in Hong Kong Chinese population Journal article
Neurobiology of Aging, 2018,Volume: 68,Page: 160.e1-160.e7
Authors:  Wang B.;  Bao S.;  Zhang Z.;  Zhou X.;  Wang J.;  Fan Y.;  Zhang Y.;  Li Y.;  Chen L.;  Jia Y.;  Li J.;  Li M.;  Zheng W.;  Mu N.;  Wang L.;  Yu Z.;  Wong D.S.M.;  Zhang Y.;  Kwan J.;  Ka-Fung Mak H.;  Ambalavanan A.;  Zhou S.;  Cai W.;  Zheng J.;  Huang S.;  Rouleau G.A.;  Yang W.;  Rogaeva E.;  Ma X.;  St George-Hyslop P.;  Chu L.W.;  Song Y.-Q.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/21
Apoe Ɛ4-negative  Late-onset Alzheimer's Disease  Mlkl  Whole Exome Sequencing  
Dihydrotanshinone I, a natural product, ameliorates DSS-induced experimental ulcerative colitis in mice Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 344,Page: 35-45
Authors:  Guo, Yanling;  Wu, Xiaxia;  Wu, Qin;  Lu, Yuanfu;  Shi, Jingshan;  Chen, Xiuping
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
15,16-dihydrotanshinone i  Ulcerative Colitis  Inflammation  Necroptosis  
Neferine, a Bisbenzylisoquinoline Alkaloid, Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis Journal article
AMERICAN JOURNAL OF CHINESE MEDICINE, 2018,Volume: 46,Issue: 6,Page: 1263-1279
Authors:  Wu, Xiaxia;  Guo, Yanling;  Min, Xiangjing;  Pei, Lixia;  Chen, Xiuping
Favorite  |  View/Download:10/0  |  Submit date:2018/10/30
Neferine  Ulcerative Colitis  Inflammation  
Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells Journal article
FREE RADICAL BIOLOGY AND MEDICINE, 2017,Volume: 108,Page: 433-444
Authors:  Sun, Wen;  Wu, Xiaxia;  Gao, Hongwei;  Yu, Jie;  Zhao, Wenwen;  Lu, Jin-Jian;  Wang, Jinhua;  Du, Guanhua;  Chen, Xiuping
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Necroptosis  C-jun N-terminal Kinase  Calcium  Ros  
Tert-butyl hydroperoxide (t-BHP) induced apoptosis and necroptosis in endothelial cells: Roles of NOX4 and mitochondrion Journal article
REDOX BIOLOGY, 2017,Volume: 11,Page: 524-534
Authors:  Zhao, Wenwen;  Feng, Haitao;  Sun, Wen;  Liu, Kang;  Lu, Jin-Jian;  Chen, Xiuping
Favorite  |  View/Download:6/0  |  Submit date:2018/10/30
Apoptosis  Necroptosis  Reactive Oxygen Species  Nox4  Mitochondria  Endothelial Cells