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Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 9,Page: 1193-1204
Authors:  Ting-ting Zhou;  Tong Zhao;  Fei Ma;  Yi-nan Zhang;  Jing Jiang;  Yuan Ruan;  Qiu-ying Yan;  Gai-hong Wang;  Jin Ren;  Xiao-wei Guan;  Jun Guo;  Yong-hua Zhao;  Ji-ming Ye;  Li-hong Hu;  Jing Chen;  Xu Shen
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Type 2 Diabetes Mellitus  Hepatic Gluconeogenesis  Ampk Signaling Pathway  (e)-3-(2-(Quinoline-4-yl)Vinyl)-1h-indol-6-ol (Qvo)  4-[2-(1h-indol-3-yl)Vinyl]Quinoline (Ivq)  Prodrug  
Metformin protects PC12 cells and hippocampal neurons from H2O (2)-induced oxidative damage through activation of AMPK pathway Journal article
JOURNAL OF CELLULAR PHYSIOLOGY, 2019,Volume: 234,Issue: 9,Page: 16619-16629
Authors:  Xia Zhao;  Zhiwen Zeng;  Uma Gaur;  Jiankang Fang;  Tangming Peng;  Shuai Li;  Wenhua Zheng
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Aging  Amp-activated Protein Kinase  Hydrogen Peroxide  Metformin  Pc12 Cells  
Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells Journal article
STEM CELL REPORTS, 2019,Volume: 13,Issue: 2,Page: 338-351
Authors:  Chengcheng Song;  Faxiang Xu;  Zhili Ren;  Yumeng Zhang;  Ya Meng;  Yiqi Yang;  Shreyas Lingadahalli;  Edwin Cheung;  Gang Li;  Weiwei Liu;  Jianbo Wan;  Yang Zhao;  Guokai Chen
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Hescs  Pyruvate  Bmp4  Glycolysis  Tca Cycle  Ampk  Wnt  Metabolism  Mesoderm  Differentiation  
n-3 Polyunsaturated fatty acids for the management of alcoholic liverdisease: A critical review Conference paper
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, Kunming, PEOPLES R CHINA, 2018-8
Authors:  Meng Wang;  Li-Juan Ma;  Yan Yang;  Zeyu Xia;  jian-Bo Wan
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Alcoholic Liver Disease  Alcoholic Steatosis  Intestinal Homeostasis  Inflammation  N-3 Polyunsaturated Fatty Acids  Oxidative Stress  
A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:  Xinhua Zhou;  Anqi Wang;  Liang Wang;  Jianhua Yin;  Li Wang;  Lijun Di;  Maggie Pui-Man Hoi;  Luchen Shan;  Xu Wu;  Yuqiang Wang
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Danshensu  Tetramethylpyrazine  Breast Cancer  Resistance  Glycolysis  P-glycoprotein  
The effects of bioactive components from the rhizome of Salvia miltiorrhiza (Danshen) on the characteristics of Alzheimer's disease Journal article
Chinese Medicine, 2019,Volume: 14
Authors:  Cheong‑Meng Chong;  Huanxing Su;  Jin‑Jian Lu;  Yitao Wang
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Alzheimer’s Disease  Danshen  Amyloid β Plaques  Neurofbrillary Tangles  Mitochondrial Dysfunction  Autophagy  
Flaxseed extract induces apoptosis in human breast cancer MCF-7 cells Journal article
Food and Chemical Toxicology, 2019,Volume: 127,Page: 188-196
Authors:  Tingyan Hu;  Kegang Linghu;  Siqi Huang;  Maurizio Battino;  Milen I. Georgiev;  Gokhan Zengin;  Defang Li;  Yun Deng;  Y.T. Wang;  Hui Cao
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Flaxseed  Mcf-7 cells  Apoptosis  Ros  Mitochondrial Membrane Potential  Dietary Supplement  
The effects of bioactive components from the rhizome of Salvia miltiorrhiza(Danshen) on the characteristics of Alzheimer’s disease Journal article
CHINESE MEDICINE, 2019
Authors:  Cheong‑Meng Chong;  Huanxing Su;  Jin‑Jian Lu;  Yitao Wang
Favorite  |  View/Download:6/0  |  Submit date:2020/04/08
Alzheimer’s Disease  Amyloid β Plaques  Neurofibrillary Tangles  Mitochondrial Dysfunction  Autophagy  Danshen  
Myricanol rescues dexamethasone‐induced muscle dysfunction via a sirtuin 1‐dependent mechanism Journal article
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2019,Volume: 10,Issue: 2,Page: 429-444
Authors:  Shengnan Shen;  Qiwen Liao;  Jingxin Liu;  Ruile Pan;  Simon Ming-Yuen Lee;  Ligen Lin1
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Autophagy  Dexamethasone  Muscle Atrophy  Myricanol  Pgc-1α  Sirt1  
Mitochondrial protective effect of neferine through the modulation of nuclear factor erythroid 2-related factor 2 signalling in ischaemic stroke Journal article
BRITISH JOURNAL OF PHARMACOLOGY, 2019,Volume: 176,Issue: 3,Page: 400-415
Authors:  Chuanhong Wu;  Jianxin Chen;  Ruocong Yang;  Feipeng Duan;  Shaojing Li;  Xiuping Chen
Favorite  |  View/Download:11/0  |  Submit date:2020/01/07