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BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1-MCM2 signaling during pregnancy Journal article
Human molecular genetics, 2018
Authors:  Xiaoling Xu;  Eric Chen;  Lihua Mo;  Lei Zhang;  Fangyuan Shao;  Kai Miao;  Jianlin Liu;  Sek Man Su;  Monica Valecha;  Un In Chan;  Hongping Zheng;  Mark Chen;  Weiping Chen;  Qiang Chen;  Haiqing Fu;  Mirit I. Aladjem;  Yanzhen He;  Chu-Xia Deng
Favorite  |  View/Download:23/0  |  Submit date:2018/12/17
Single-cell RNA-Seq reveals cell heterogeneity and hierarchy within mouse mammary epithelia Journal article
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018,Volume: 293,Issue: 22,Page: 8315-8329
Authors:  Sun, Heng;  Miao, Zhengqiang;  Zhang, Xin;  Chan, Un In;  Su, Sek Man;  Guo, Sen;  Wong, Chris Koon Ho;  Xu, Xiaoling;  Deng, Chu-Xia
Favorite  |  View/Download:30/0  |  Submit date:2018/10/30
Mammary Gland  Development  Breast Cancer  Biomarker  Cell Differentiation  Stem Cells  cdh5+cell  Mammary Stem Cells (Mascs)  Single Cell Rna-seq  
Inhibition of Estrogen Signaling Reduces the Incidence of BRCA1-associated Mammary Tumor Formation Journal article
International journal of biological sciences, 2018,Volume: 14,Issue: 12,Page: 1755-1768
Authors:  Baek H.J.;  Kim S.E.;  Choi E.K.;  Kim J.K.;  Shin D.H.;  Park E.J.;  Kim T.H.;  Kim J.-Y.;  Kim K.G.;  Deng C.-X.;  Kim S.S.
Favorite  |  View/Download:8/0  |  Submit date:2018/12/13
Brca1  Cancer Prevention  Estrogen  Fulvestrant  
Osthole inhibited TGF beta-induced epithelial-mesenchymal transition (EMT) by suppressing NF-kappa B mediated Snail activation in lung cancer A549 cells Journal article
CELL ADHESION & MIGRATION, 2017,Volume: 11,Issue: 5-6,Page: 464-475
Authors:  Feng, Haitao;  Lu, Jin-Jian;  Wang, Yitao;  Pei, Lixia;  Chen, Xiuping
View  |  Adobe PDF(1506Kb)  |  Favorite  |  View/Download:78/7  |  Submit date:2018/10/30
Emt  Nf-kappa b  Osthole Snail  Tgf-beta 1  
Adapted resistance to the knockdown effect of shRNA-derived Srsf3 siRNAs in mouse littermates Journal article
International Journal of Biological Sciences, 2015,Volume: 11,Issue: 11,Page: 1248-1256
Authors:  Ajiro M.;  Jia R.;  Wang R.-H.;  Deng C.-X.;  Zheng Z.-M.
Favorite  |  View/Download:4/0  |  Submit date:2018/12/13
Shrnas  Srsf3  Transgenic Mouse  
BRCA1 And Estrogen/Estrogen Receptor In Breast Cancer: Where They Interact? Journal article
International Journal of Biological Sciences, 2014,Volume: 10,Issue: 5,Page: 566-575
Authors:  Li Wang;  Li-Jun Di
Favorite  |  View/Download:1/0  |  Submit date:2019/01/04
Estrogen  Oxidative Stress  Brca1  Mammary Gland Development  Ros  Breast Cancer  Cell Metabolism  Estrogen Receptor  
Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland Journal article
DEVELOPMENT, 2002,Volume: 129,Issue: 17,Page: 4159-4170
Authors:  Gang Li;  Gertraud W. Robinson;  Ralf Lesche;  Hilda Martinez-Diaz;  Zhaorong Jiang;  Nora Rozengurt;  Kay-Uwe Wagner;  De-Chang Wu;  Timothy F. Lane;  Xin Liu;  Lothar Hennighausen;  Hong Wu
Favorite  |  View/Download:2/0  |  Submit date:2019/01/22
Pten  Mammary Development  Cowden’s Disease  Ductal Growth  Apoptosis