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Discovery of fused bicyclic derivatives of 1H-pyrrolo[1,2-c]imidazol-1-one as VDR signaling regulators Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2019,Volume: 27,Issue: 17,Page: 3879-3888
Authors:  Bin Xu;  Mo-Yu Ding;  Zhibing Weng;  Zheng-Qing Li;  Feng Li;  Xia Sun;  Qiu-Ling Chen;  Yi-Tao Wang;  Ying Wang;  Guo-Chun Zhou
Favorite  |  View/Download:12/0  |  Submit date:2019/11/22
1h-pyrrolo[1,2-c]Imidazol-1-one  Vitamin d Receptor (Vdr)  Autophagy  Apoptosis  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
View  |  Adobe PDF(2009Kb)  |  Favorite  |  View/Download:493/53  |  Submit date:2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
MK2 mediates macrophage activation and acute lung injury by regulating let-7e miRNA Journal article
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2018,Volume: 315,Issue: 3,Page: L371-L381
Authors:  Wu, Yaxian;  He, Huiqiong;  Ding, Yunhe;  Liu, Sirui;  Zhang, Depeng;  Wang, Jun;  Jiang, Hongchao;  Zhang, Dan;  Sun, Lei;  Ye, Richard D.;  Qian, Feng
View  |  Adobe PDF(2092Kb)  |  Favorite  |  View/Download:205/10  |  Submit date:2018/10/30
acute lung injury  let-7e  lipopolysaccharides  macrophage  MAPK-activated protein kinase 2  miRNA  MK2  
Interference of Quercetin on Astragalus Polysaccharide-Induced Macrophage Activation Journal article
MOLECULES, 2018,Volume: 23,Issue: 7
Authors:  Li, Zhi-Peng;  Liu, Hong-Bing;  Zhang, Quan-Wei;  Li, Li-Feng;  Bao, Wan-Rong;  Ma, Dik-Lung;  Leung, Chung-Hang;  Bian, Zhao-Xiang;  Lu, Ai-Ping;  Han, Quan-Bin
View  |  Adobe PDF(1815Kb)  |  Favorite  |  View/Download:207/10  |  Submit date:2018/10/30
Astragalus Polysaccharide  Quercetin  Cytokines  Macrophage  Foods  
Discovery and preliminary SAR of 14-aryloxy-andrographolide derivatives as antibacterial agents with immunosuppressant activity Journal article
RSC ADVANCES, 2018,Volume: 8,Issue: 17,Page: 9440-9456
Authors:  Li, Feng;  Li, Xiao-Min;  Sheng, Dekuan;  Chen, Shao-Ru;  Nie, Xin;  Liu, Zhuyun;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Wang, Ying;  Zhou, Guo-Chun
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Siegesbeckia pubescens Makino inhibits Pam3CSK4-induced inflammation in RAW 264.7 macrophages through suppressing TLR1/TLR2-mediated NF-ΚB activation Journal article
Chinese Medicine (United Kingdom), 2018,Volume: 13,Issue: 1
Authors:  Sang W.;  Zhong Z.;  Linghu K.;  Xiong W.;  Tse A.K.W.;  Cheang W.S.;  Yu H.;  Wang Y.
Favorite  |  View/Download:6/0  |  Submit date:2018/10/31
Inflammation  Nf-κb  Pam3csk4  Siegesbeckia Pubescens Makino  Toll-like Receptor 1/2  
Identification and characterization of a specific 13-miRNA expression signature during follicle activation in the zebrafish ovary Journal article
BIOLOGY OF REPRODUCTION, 2018,Volume: 98,Issue: 1,Page: 42-53
Authors:  Wong, Queenie Wing-Lei;  Sun, Ming-An;  Lau, Shuk-Wa;  Parsania, Chirag;  Zhou, Shaolong;  Zhong, Silin;  Ge, Wei
Favorite  |  View/Download:21/0  |  Submit date:2018/10/30
Microrna  Folliculogenesis  Ovary  Zebrafish  
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:  Guo, Baojian;  Hu, Shengquan;  Zheng, Chengyou;  Wang, Hongyu;  Luo, Fangcheng;  Li, Haitao;  Cui, Wei;  Yang, Xifei;  Cui, Guozhen;  Mak, Shinghung;  Choi, Tony Chung-Lit;  Ma, Edmond Dik-Lung;  Wang, Yuqiang;  Lee, Simon Ming Yuen;  Zhang, Zaijun;  Han, Yifan
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Parkinson's disease  SU4312  Neuroprotection  Myocyte enhancer factor 2D  Monoamine oxidase-B  
Nepetoidin B, a Natural Product, Inhibits LPS-stimulated Nitric Oxide Production via Modulation of iNOS Mediated by NF-κB/MKP-5 Pathways Journal article
Phytotherapy Research, 2017,Volume: 31,Issue: 7,Page: 1072-1077
Authors:  Wu X.;  Gao H.;  Sun W.;  Yu J.;  Hu H.;  Xu Q.;  Chen X.
Favorite  |  View/Download:5/0  |  Submit date:2018/12/28
Inducible Nitric Oxide Synthase, Nf-κb, Mkp-5  Nepetoidin b  Nitric Oxide  
Cucurbitane Glucosides from the Crude Extract of Siraitia grosvenorii with Moderate Effects on PGC-1α Promoter Activity Journal article
Journal of Natural Products, 2017,Volume: 80,Issue: 5,Page: 1428-1435
Authors:  Niu B.;  Ke C.-Q.;  Li B.-H.;  Li Y.;  Yi Y.;  Luo Y.;  Shuai L.;  Yao S.;  Lin L.-G.;  Li J.;  Ye Y.
Favorite  |  View/Download:4/0  |  Submit date:2019/01/15