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The metabolic footprint during adipocyte commitment highlights ceramide modulation as an adequate approach for obesity treatment Journal article
EBioMedicine, 2020,Volume: 51
Authors:  Hou,Weilong;  Chen,Qiang;  Wang,Haitao;  Qiu,Pengxiang;  Lyu,Xueying;  Chen,Weiping;  Chua,Melvin L.K.;  Chinn,Y. Eugene;  Deng,Chu Xia;  Wang,Ruihong
Favorite | View/Download:74/0 | TC[WOS]:0 TC[Scopus]:1 | Submit date:2020/09/16
Adipogenesis  Apoptosis  Ceramide  Epigenetic modification  Metabolic landscape  Metabolomics  Obesity  
Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism Journal article
Cell Metabolism, 2019,Volume: 30,Issue: 2,Page: 385-401.e9
Authors:  Collin de l'Hortet,Alexandra;  Takeishi,Kazuki;  Guzman-Lepe,J.;  Morita,Kazutoyo;  Achreja,Abhinav;  Popovic,Branimir;  Wang,Yang;  Handa,Kan;  Mittal,Anjali;  Meurs,Noah;  Zhu,Z.;  Weinberg,F.;  Salomon,Michael;  Fox,I. J.;  Deng,Chu Xia;  Nagrath,Deepak;  Soto-Gutierrez,Alejandro
Favorite | View/Download:73/0 | TC[WOS]:10 TC[Scopus]:15 | Submit date:2020/09/16
cellular engineering  hepatic differentiation  human fatty liver  human iPSCs  liver metabolism  NAFLD  NASH  SIRT1  
A combination of Pueraria lobata and Silybum marianum protects against alcoholic liver disease in mice Journal article
PHYTOMEDICINE, 2019,Volume: 58
Authors:  Feng Ruibing;  Chen Jie-Hua;  Liu Cong-Hui;  Xia Fang-Bo;  Xiao Zeyu;  hang Xuguang;  Wan Jian-Bo
Favorite | View/Download:19/0 | TC[WOS]:3 TC[Scopus]:9 | Submit date:2020/04/22
SiL.bum Marianum(L.)Gaerth  Pueraria Lobata(Wild.)Ohwi  Alcoholic Liver Disease  Hepatic Inflammation  Intestinal Barrier Dysfunction  
Myricanol mitigates lipid accumulation in 3T3-L1 adipocytes and high fat diet-fed zebrafish via activating AMP-activated protein kinase Journal article
Food Chemistry, 2019,Volume: 270,Page: 305-314
Authors:  Shen S.;  Liao Q.;  Feng Y.;  Liu J.;  Pan R.;  Lee S.M.-Y.;  Lin L.
Favorite | View/Download:29/0 | TC[WOS]:12 TC[Scopus]:16 | Submit date:2018/11/06
Adipogenesis  Amp-activated Protein Kinase  Insulin Sensitivity  Lipid Accumulation  Myricanol  Zebrafish  
Hepatoprotective Effect of Jianpi Huoxue Formula on Nonalcoholic Fatty Liver Disease Induced by Methionine-Choline-Deficient Diet in Rat Journal article
BIOMED RESEARCH INTERNATIONAL, 2019,Volume: 2019
Authors:  Yu Feng;  Yan Chen;  Binrui Yang;  Qingping Lan;  Tao Wang;  Guozhen Cui;  Zhitao Ren;  I. Cheong Choi;  George Pak-Heng Leung;  Fenggen Yan;  Dacan Chen;  Hon Ho Yu;  Simon Ming Yuen Lee
Favorite | View/Download:249/0 | TC[WOS]:1 TC[Scopus]:2 | Submit date:2020/01/16
Myricanol modulates skeletal muscle-adipose tissue crosstalk to alleviate high-fat diet-induced obesity and insulin resistance Journal article
BRITISH JOURNAL OF PHARMACOLOGY, 2019,Volume: 176,Issue: 20,Page: 3983-4001
Authors:  Shen, SN;  Liao, QW;  Zhang, T;  Pan, RL;  Lin, LG
Favorite | View/Download:21/0 | TC[WOS]:3 TC[Scopus]:8 | Submit date:2020/03/20
Serially coupled reversed phase-hydrophilic interaction liquid chromatography-tailored multiple reaction monitoring, a fit-for-purpose tool for large-scale targeted metabolomics of medicinal bile Journal article
ANALYTICA CHIMICA ACTA, 2018,Volume: 1037,Page: 119-129
Authors:  Song, Qingqing;  Liu, Wenjing;  Chen, Xiaojia;  Li, Jun;  Li, Peng;  Yang, Fengqing;  Wang, Yitao;  Song, Yuelin;  Tu, Pengfei
Adobe PDF | Favorite | View/Download:875/3 | TC[WOS]:15 TC[Scopus]:21 | Submit date:2018/10/30
Large-scale Targeted Metabolomics  Serially Coupled Rplc-hilic  Tailored Multiple Reaction Monitoring  Medicinal Bile  Bile Acids  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
View | Adobe PDF | Favorite | View/Download:1442/102 | TC[WOS]:3 TC[Scopus]:5 | Submit date:2018/10/30
Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Pinostrobin Exerts Neuroprotective Actions in Neurotoxin-Induced Parkinson's Disease Models through Nrf2 Induction Journal article
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018,Volume: 66,Issue: 31,Page: 8307-8318
Authors:  Li, Chuwen;  Tang, Benqin;  Feng, Yu;  Tang, Fan;  Hoi, Maggie Pui-Man;  Su, Ziren;  Lee, Simon Ming-Yuen
Favorite | View/Download:25/0 | TC[WOS]:11 TC[Scopus]:19 | Submit date:2018/10/31
Pinostrobin  Parkinson's Disease  Neurotoxin  Nrf2  
Water soluble fraction from ethanolic extract of Clausena lansium seeds alleviates obesity and insulin resistance, and changes the composition of gut microbiota in high-fat diet-fed mice Journal article
JOURNAL OF FUNCTIONAL FOODS, 2018,Volume: 47,Page: 192-199
Authors:  Shen, Shengnan;  Liao, Qiwen;  Huang, Li;  Li, Dan;  Zhang, Qingwen;  Wang, Yitao;  Lee, Simon Ming-Yuen;  Lin, Ligen
View | Adobe PDF | Favorite | View/Download:770/43 | TC[WOS]:3 TC[Scopus]:6 | Submit date:2018/10/30
Clausena Lansium  Fat Mass Gain  Insulin Sensitivity  Gut Microbiota  Wampee