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Sodium tanshinone IIA sulfonate promotes endothelial integrity via regulating VE-cadherin dynamics and RhoA/ROCK-mediated cellular contractility and prevents atorvastatin-induced intracerebral hemorrhage in zebrafish Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 350,Page: 32-42
Authors:  Zhou, Zhong-Yan;  Huang, Bin;  Li, Shang;  Huang, Xiao-Hui;  Tang, Jing-Yi;  Kwan, Yiu Wa;  Hoi, Pui Man;  Lee, Simon Ming-Yuen
Favorite  |  View/Download:9/0  |  Submit date:2018/10/30
Sodium tanshinone IIA sulfonate  Salvia miltiorrhiza  Hemorrhagic stroke  Atorvastatin  ROCK  
ROCK in CNS: Different Roles of Isoforms and Therapeutic Target for Neurodegenerative Disorders Journal article
CURRENT DRUG TARGETS, 2017,Volume: 18,Issue: 4,Page: 455-462
Authors:  Chong, Cheong-Meng;  Ai, Nana;  Lee, Simon Ming-Yuen
Favorite  |  View/Download:10/0  |  Submit date:2018/10/30
Axonal Regeneration  Central Nervous System  Fasudil  Isoforms  Limk  Neurodegenerative Diseases  Rock  
LIM kinase 1 promotes endothelial barrier disruption and neutrophil infiltration in mouse lungs Journal article
Circulation Research, 2009,Volume: 105,Issue: 6,Page: 549-556
Authors:  Gorovoy M.;  Han J.;  Pan H.;  Welch E.;  Neamu R.;  Jia Z.;  Predescu D.;  Vogel S.;  Minshall R.D.;  Ye R.D.;  Malik A.B.;  Voyno-Yasenetskaya T.
Favorite  |  View/Download:1/0  |  Submit date:2018/11/07
Actin cytoskeleton  Acute lung injury  Endothelial barrier function  Inflammation  LIMK1  Neutrophil infiltration  RhoA