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Cryptotanshinone inhibits TNF-α-induced LOX-1 expression by suppressing reactive oxygen species (ROS) formation in endothelial cells Journal article
Korean Journal of Physiology and Pharmacology, 2016,Volume: 20,Issue: 4,Page: 347-355
Authors:  Ran X.;  Zhao W.;  Li W.;  Shi J.;  Chen X.
Favorite  |  View/Download:2/0  |  Submit date:2018/12/28
Cryptotanshinone  Endothelial Cells  Lox-1  Ros  Tnf-α  
Lipopolysaccharide induced LOX-1 expression via TLR4/MyD88/ROS activated p38MAPK-NF-κB pathway Journal article
Vascular Pharmacology, 2014,Volume: 63,Issue: 3,Page: 162
Authors:  Zhao W.;  Ma G.;  Chen X.
Favorite  |  View/Download:12/0  |  Submit date:2018/10/30
Endothelial Cells  Lipopolysaccharide  Lox-1  Ros  
Multi-Target Drugs: The Trend of Drug Research and Development Journal article
PLOS ONE, 2012,Volume: 7,Issue: 6,Page: 30-46
Authors:  Lu, JJ (Lu, Jin-Jian);  Pan, W (Pan, Wei);  Hu, YJ (Hu, Yuan-Jia);  Wang, YT (Wang, Yi-Tao
View  |  Adobe PDF(1050Kb)  |  Favorite  |  View/Download:84/3  |  Submit date:2018/11/01
Cancer-therapy  Alzheimers-disease  Parkinsons-disease  Attractive Target  Natural-products  b Inhibitors  Discovery  Atherosclerosis  Acetylcholinesterase  Proliferation  
Ox-LDL-induced LOX-1 expression in vascular smooth muscle cells: Role of reactive oxygen species Journal article
Fundamental and Clinical Pharmacology, 2011,Volume: 25,Issue: 5,Page: 572
Authors:  Sun Y.;  Chen X.
Favorite  |  View/Download:20/0  |  Submit date:2018/10/30
Lectin-like Oxidized Low Density Lipoprotein Receptor-1  Oxidized Low Density Lipoprotein  Reactive Oxygen Species  Vascular Smooth Muscle Cells  
The reciprocal relationship between adiponectin and LOX-1 in the regulation of endothelial dysfunction in ApoE knockout mice Journal article
American Journal of Physiology - Heart and Circulatory Physiology, 2010,Volume: 299,Issue: 3
Authors:  Chen X.;  Zhang H.;  McAfee S.;  Zhang C.
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Aorta  Apolipoprotein e  Cytokine  Lectin-like Oxidized Low-density Lipoprotein Receptor  Oxidative Stress  Vasorelaxation  
“Ox-LDL-LOX-1-ROS” Signaling Pathway Involvement in Foam Cell Formation Journal article
Chinese Journal of Arteriosclerosis, 2010,Volume: 18,Issue: 7,Page: 577-581
Authors:  Chen Xiuping;  Zhao Haiyu;  Zhong Zhangfeng;  Xu Zengtao;  Wang Yitao
Favorite  |  View/Download:4/0  |  Submit date:2018/11/01
Atherosclerosis  Oxidized Low Density Lipoprotein  Lectin-like Oxidized Low Density Lipoprotein Receptor-1  Reactive Oxygen Species  Foam Cell Formation  
Role of TNF-α in vascular dysfunction Journal article
Clinical Science, 2009,Volume: 116,Issue: 3,Page: 219-230
Authors:  Hanrui Zhang;  Yoonjung Park;  Junxi Wu;  Xiu ping Chen;  Sewon Lee;  Jiyeon Yang;  Kevin C. Dellsperger;  Cuihua Zhang
Favorite  |  View/Download:21/0  |  Submit date:2019/01/08
Inflammation  Macrovascular Circulation  Microvascular Circulation  Nitric Oxide  Reactive Oxygen Species (Ros)  Tumour Necrosis Factor-α (Tnf-α)  
Adiponectin, an Unlocking Adipocytokine Journal article
CARDIOVASCULAR THERAPEUTICS, 2009,Volume: 27,Issue: 1,Page: 59-75
Authors:  Sun, YY;  Xun, KL;  Wang, CG;  Zhao, HY;  Bi, HC;  Chen, XP;  Wang, YT
View  |  Adobe PDF(741Kb)  |  Favorite  |  View/Download:88/2  |  Submit date:2018/11/01
Adiponecitn  Biomarker  Drug Target  Exercise  Gender Difference  Inflammation  
Advanced glycation end products serve as ligands for lectin-like oxidized low-density lipoprotein receptor-1(LOX-1): biochemical and binding characterizations assay. Journal article
Cell biochemistry and function, 2008,Volume: 26,Issue: 7,Page: 760-770
Authors:  Chen X.;  Zhang T.;  Du G.
Favorite  |  View/Download:1/0  |  Submit date:2018/12/28
Target validation: A door to drug discovery Journal article
Drug Discoveries & Therapeutics, 2007,Volume: 1,Issue: 1,Page: 23-29
Authors:  Xiu-Ping Chen;  Guan-Hua Du
Favorite  |  View/Download:2/0  |  Submit date:2019/01/08
Drug Discovery  Drug Target  Drug Target Validation  High-throughput Screening  Lectin-like Oxidized Low-density Lipoprotein Receptor-1